Simultaneous determination of five constituents in "Tzyy-Yun-Gau" medicine by high performance liquid chromatography

Journal of Food and Drug Analysis

Volumn 8, Issue 4, 2000, Pages 304-308

  Lay, Horng Liang ^b   Shih, I Jen ^a   Yeh, Chih Ho ^a   Lin, Chwan Fwu ^a   Liang, J Wen ^a  

^a Pharmaceutical Indust Technol D   (Taiwan)

^b Department of Plant Industry   (Taiwan)

Author keywords

, dimethylacrylshikonin; Acetylshikonin; Angelicae Radix; Arnebiae Radix; Deoxyshikonin; Ferulic acid; Shikonin; Tzyy Yun Gau

Indexed keywords

ACETIC ACID; ACETONITRILE; ACETYLSHIKONIN; BETA,BETA DIMETHYLACRYLSHIKONIN; CHINESE DRUG; DEOXYSHIKONIN; FERULIC ACID; METHANOL; SHIKONIN; TZYY YUN GAU; UNCLASSIFIED DRUG;

ARTICLE; CHINESE MEDICINE; DRUG DETERMINATION; DRUG MIXTURE; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PARTITION CHROMATOGRAPHY; SPECTRAL SENSITIVITY; ULTRAVIOLET RADIATION;

EID: 0034461946     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Pharmaceutical Industry Technology and Development Center. 1997. HPLC and CE Methods for Herbal Products. Volume (1). Taipei, Taiwan, R.O.C.
2. Lay, H. L., Chan, H. J. and Lin, C. F. 1997. Simultaneous analysis of six components in "Chai-Hu-Kuei-Chih-Tang" by high performance liquid chromatography. J. Food Drug Anal. 5: 381-390.
3. Takahashi, S., Hikino, H. and Sasaki, Y. 1958. Studies on Umbelliferous plants. IX. Studies on "Toki". (9). Components of the Root of Angelica acutiloba and A. acutiloba var. sugiyamae. Yakugaku Zasshi 79: 1156-1159.
4. Mitsuhashi, H., Nagai, U. and Muramatsu, T. 1961. Studies on the constituents of Umbelliferae plants. III. Structure of ligustilide. Chem. Pharm. Bull. 9: 115-119.
5. Mitsuhashi, H., Muramatsu, T., Nagai, U., Nakano, T. and Ueno, K. 1963. Studies on the constituents of Umbelliferae plants. VIII. Distribution of alkylphthalides in Umbelliferae plants. Chem. Pharm. Bull. 11: 1317-1319.
6. Bohrmann, H., Stahl, E. and Mitsuhashi, H. 1967. Studies on the constituents of Umbelliferae plants. XIII. Chromatographic studies on the constituents of Cnidium officinale Makino. Chem. Pharm. Bull. 15: 1606-1608.
7. Ruo, T. I., Wu, T. Y. and Yang, Y. Y. 1967. Comparison of chemical composition and effect on animal feeding of native and imported. J. Chinese Agric. Chem. Soc. 5: 93-99.
8. Yamagishi, T., Kaneshima, H., Kinoshita, Y. and Mori, M. 1974. Studies on the standardization of crude drugs produced in Hokkaido (part 5). On the existence of Ligustilide in Angelicae Radix (Touki). Ann. Rep. Hokkaido Metr. Res. Lab. P. H. 24: 47-51.
9. Yamagishi, T., Kaneshima, H., Kinoshita, Y. and Honma, S. 1975. Studies on the standardization of crude drugs produced in Hokkaido (part 7). The ether soluble components of Angelicae Radix (Touki). Ann. Rep. Hokkaido Metr. Res. Lab. P. H. 25: 21-24.
10. Yamagishi, T., Kaneshima, H., Kinoshita, Y. and Honma, S. 1975. Studies on the standardization of crude drugs produced in Hokkaido (part 8). The comparison quality and components of Touki cultivated in different places. Ann. Rep. Hokkaido Metr. Res. Lab. P. H. 25: 25-29.
11. Lin, M., Ju, C. D., Sun, C. M. and Fang, C. C.1979. Studies on the chemical component of Angelica sinensis Diels. Acta Pharmaceutica Sinica 14: 529-534.
12. Fang, H. G., Lu, R. M., Liu, G. S. and Liu, T. C. 1979. Studies on the components of essential oils. Acta Pharmaceutica Sinica 14: 617-623.
13. Lu, R. M., Ho, L. Y., Fang, H. G. and Zhang, X. Q. 1980. Thin layer chromatography and densitometry of ligustilide in Umbelliferae plants. Acta Pharmaceutica Sinica 15:371-374.
14. Tomoda, M. and Katoh, K. 1982. Methods for identification of Angelicae Radix by means of electrophoresis with color and precipitation reactions. Shoyakugaku Zasshi 36: 319-324.
15. Yamada, H., Kiyohara, H., Cyong, J. C., Kojima, Y., Kumazawa, Y. and Otsuka, Y. 1984. Studies on polysaccharides from Angelicae Radix (III). Shoyakugaku Zasshi 38: 111-117.
16. Yamada, H., Kiyohara, H. and Otsuka, Y. 1984. Characterization of a water-solution glucan from Angelica acutiloba. Phytochemistry 23: 587-590.
17. Tomoda, M., Ichikawa, M. and Shimizu, N. 1986. Pectic substances. III. The major pectin from the roots of Angelica acutiloba. Chem. Pharm. Bull. 34: 4992-4996.
18. Toriizuka, K., Nishiyama, P., Adachi, I., Kawashiri, N., Ueno, M., Trasawa, K. and Horikoshi, I. 1986. Isolation of a platelet aggregation inhibitor from Angelicae Radix. Chem. Pharm. Bull. 34: 5011-5015.
19. Lay, H. L., Lin, W. Y., Motota, Y., Tamai, F. and Tanabe, T. 1992. Effects of manurial elements on the plant growth and yield, extract contents, Ligustilide, Butylidene Phthalide contents of Angelica Radix. Shoyakugaku Zasshi 46: 321-327.
20. Lay, H. L., Lin, W. Y., Motota, Y., Kikuchi, N., Miki, T. and Tanabe, T. 1992. Effects of temperature on the plant growth physiology, yield and the quality of Angelica Radix. Shoyakugaku Zasshi 46: 328-338.
21. Lay, H. L., Lin, W. Y., Motota, Y., Tamai, F. and Tanabe, T. 1992. Season variation of plant growth, yield, extract and Ligustilide contents in different species of crude drug "Tou-Ki". Shoyakugaku Zasshi 46: 365-371.
22. Kikuchi, N., Lay, H. L., Tanabe, T. and Miki, T. 1992. High performance liquid chromatographic separation and quantitative determination of Ligustilide in the Angelica plant using fluorometric detection. Acta Chromatographica 1: 23-33.
23. Lay, H. L., Lin, W. Y., Motota, Y., Tamai, F. and Tanabe, T. 1993. Effects of root-cutting treatments on the controlling the bolting and plant growth, yield and the quality of Angelica Radix. Shoyakugaku Zasshi 50: 367-376.
24. Tanaka, Y. and Odani, T. 1972. Pharmacodynamic study on "Shiunko" I. Antibacterial effect of "Shiunko". Yakugaku Zasshi 92: 525-530.
25. Yoshizaki, F., Hisamichi, S., Kondo, Y., Sato, Y. and Nozoe, S. 1982. Studies on Shikon. III. New Furylhydroquinone derivatives, Shikonofurans A, B, C, D and E, from Lithospermum erythrorhizon. Chem. Pharm. Bull. 30: 4407-4411.
26. Fukui, H., Yazaki, K. and Tabata, M. 1984. Two phenolic acids from Lithospermum erythrorhizon cell suspension cultures. Phytochemistry 23: 2398-2399.
27. Konno, C., Mizuno, T. and Hikino, H. 1985. Isolation and hypoglycemic activity of lithospermans A,B and C, glycans of Lithospermum erythrorhizon roots. Planta Medica 51: 157-158.
28. Honda, G., Sakakibara, F., Yazaki, K. and Tabata, M. 1988. Isolation of deoxyshikonin, an ntidermatophytic principle from Lithospermum erythrorhizon cell cultures. J. Nat. Prod. 51: 152-154.
29. Roeder, E. and Rengel, B. 1990. Pyrrolizidine alkaloids from Lithospermum erythrorhizon. Phytochemistry 29: 690-693.
30. Chang, Y. S., Kuo, S. C., Weng, S. H., Jan, S. C., Ko, F. N. and Teng, C. M. 1993. Inhibition of platelet aggregation of shikonin derivatives isolated from Arnebia euchroma. Planta Med. 59:401-403.
31. Ko, F. N., Lee, Y. S., Kuo, S. C., Chang, Y. S. and Teng, C. M. 1995. Inhibition of platelet activation by shikonin derivatives isolated from Arnebia euchroma. Biochim. Biophys. Acta 1268: 329-334.
32. Identification and assay for shikonin in Tzyy-Yun-Gau. 1996. In "A Practical Guide to the Analysis of Chinese Medicine Volume (9)-HPLC in Pharmaceutical Preparations". 1st ed. pp.45-47. National Laboratories of Foods and Drugs, Department of Health, Executive Yuan, Taiwan, R.O.C.
33. Hsu, H. Y. and Hsu, C. S. 1980. Commonly Used Chinese Herb Formulas with Illustrations, pp.514. Oriental Healing Arts Institute. Taiwan, R.O.C.