Selectivity and potency of agonists for the three subtypes of cloned human β-adrenoceptors expressed in Chinese hamster ovary cells

Tohoku Journal of Experimental Medicine

Volumn 192, Issue 3, 2000, Pages 181-193

  Yanagisawa, Teruyuki ^a   Sato, Takeya ^a,b   Yamada, Hiroaki ^a   Sukegawa, Jun ^a   Nunoki, Kazuo ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

BRL37344; Cloned human 3 adrenoceptor; Constitutive activity; Isoproterenol; N 5984

Indexed keywords

4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; 5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; 6 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,4 BENZODIOXAN 2 CARBOXYLIC ACID; 6 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 2,3 DIHYDRO 1,4 BENZODIOXINE 2 CARBOXYLIC ACID; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; ISOPRENALINE; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CHO CELL; CONCENTRATION RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; LIGAND BINDING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY;

ADRENERGIC BETA-AGONISTS; ANIMALS; CARBOXYLIC ACIDS; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CYCLIC AMP; DIOXINS; DIOXOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOLAMINES; HUMANS; ISOPROTERENOL; MOLECULAR STRUCTURE; PROTEIN ISOFORMS; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA; RECOMBINANT PROTEINS;

EID: 0034461456     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.192.181     Document Type: Article

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