LC-NMR: A new tool to expedite the dereplication and identification of natural products

Journal of Industrial Microbiology and Biotechnology

Volumn 25, Issue 6, 2000, Pages 342-345

  Bobzin, S C ^a   Yang, S ^a   Kasten, T P ^a  

^a MONSANTO COMPANY   (United States)

Author keywords

Aaptamine; Dereplication; LC NMR; Natural products

Indexed keywords

AAPTAMINE; AAPTOSINE; ENZYME INHIBITOR; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG STRUCTURE; ENZYME INHIBITION; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SCREENING; SPONGE (PORIFERA);

AAPTOS; PORIFERA;

EID: 0034460393     PISSN: 13675435     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jim.7000057     Document Type: Article

References (8)

1. Strategies for database dereplication of natural products
2. Structures of biologically active minor bases related to paragracine from Parazoanthus gracilis
3. Structures of physiologically active substances isolated from the Okinawan marines sponges
4. Increased speed and accuracy of structural determination of biologically active natural products using LC-MS
5. Aaptosine - A new cytotoxic 5,8-diazabenz [c,d] azulene alkaloid from the Red Sea Sponge Aaptos sp.
6. Dereplication of natural products using LC/MS
7. WET solvent suppression and its application to LC-NMR and high-resolution NMR spectroscopy