Cyclosporin A metabolism in brown bullhead, Ameriurus nebulosus

Fish Physiology and Biochemistry

Volumn 23, Issue 3, 2000, Pages 257-264

  Jegorov, A ^a   Halada, P ^b   Safarcik K ^c  

^a Research Unit   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c UNIVERSITY HOSPITAL OSTRAVA   (Czech Republic)

Author keywords

Brown bullhead; Cyclic peptides; Cyclosporin; Mass spectrometry; Metabolites

Indexed keywords

CYCLOPEPTIDE; CYCLOSPORIN A; DRUG METABOLITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APATHY; ARTICLE; BILE LEVEL; CATFISH; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG EXCRETION; DRUG METABOLISM; DRUG STRUCTURE; DRUG TOLERABILITY; FUNGUS; INTESTINE ABSORPTION; LARVA; LIVER LEVEL; MASS SPECTROMETRY; MOSQUITO; NONHUMAN; TOXICITY TESTING; VESTIBULAR DISORDER;

AMEIURUS NEBULOSUS; AMERIURUS; AMERIURUS NEBULOSUS; ANIMALIA; COTTUS GOBIO; FUNGI; MAMMALIA; VERTEBRATA;

EID: 0034458334     PISSN: 09201742     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007844212439     Document Type: Article

References (29)

1. Immunochemical relationships of cytochrome P450 3A-like proteins in teleost fish
2. Mass spectrometric determination of the amino acid sequence of peptides and proteins
3. 9desmethyl-cyclosporine
4. The hemodynamic-effects of Cremophor-E1
5. Preparative chromatographic purification of cyclosporine metabolites
6. The cytochrom P-450 system in fish, aquatic toxicology and environmental monitoring
7. An acid metabolite of cyclosporine
8. Susceptibility of channel catfish (Ictalurus punctatus) and brown bullhead (Ameriurus nebulosus) to oxidative stress: A comparative study
9. Sequencing of cyclosporins by fast atom bombardment and linked-scan mass spectrometry
10. Distinguishing isobaric amino acid in sequence analysis of cyclosporins by fast atom bombardment and linked-scan mass spectrometry
11. Dietary modulation of phase 1 and phase 2 activities with benzo(A)pyrene and related compounds in the intestine but not the liver of the channel catfish, Ictalurus punctatus
12. Cyclosporins from Tolypocladium terricola
13. Cloning, sequencing, and tissue expression of Cyp3A27, a new member of the Cyp3A subfamily from embrionic and adult rainbow-trout livers
14. Identification and analysis of nine metabolites of cyclosporine in whole blood by liquid chromatography 2. Comparison of patient's results
15. Histamine-release and hypotensive reactions in dogs by solubilysing agents and fatty-acids - Analysis of various components in Cremophor E1 and development of a compound with reduced toxicity
16. An electron and fluorescence microscopic study of LLC-Pk1 cells, a kidney epithelial-cell line - Normal morphology and cyclosporine-A induced and Cremophor-induced alterations
17. Immunochemical characterization of hepatic cytochrome-P450 isoenzymes in the channel catfish - Assessment of sexual, developmental and treatment-related effects
18. Metabolism of the new immunosuppressor cyclosporin G by human liver cytochromes P450
19. Detection of a P-glycoprotein related pump in chironomus larvae and its inhibition by verapamil and cyclosporine-A
20. Cyclosporine metabolism by rat liver microsomes. Evidence for involvement of enzyme(s) other than cytochromes P-450 3A
21. Cyclosporin D hydroperoxide, a new metabolite of Tolypocladium terricola
22. Comparative studies of eleven isolates of the fungal etomopathogen Tolypocladium cylindrosporum and two isolates of Tolypocladium extinguens
23. Nomenclature for hydrocarbon-inducible cytochrome-P450 in fish
24. A rifampicin-induced hepatic microsomal enzyme system for the generation of cyclosporine metabolites
25. Neue cyclosporine aus Tolypocladium inflatum, die cyclosporine K-Z
26. Species-specific cyclosporine metabolism
27. Tolypocladium terricola sp. N., a new mosquito-killing species of the genus Tolypocladium Gams
28. Cyclosporine and analogues - Isolation and synthesis - Mechanism of action and structural requirements for pharmacological activity
29. Species differences in the hepatic and intestinal metabolism of cyclosporine