Androstenedione treatment of pregnant baboons at 0.7-0.8 of Gestation promotes a premature forward shift in the nocturnal maternal plasma estradiol surge relative to progesterone and increases myometrial contraction activity

Endocrinology

Volumn 141, Issue 9, 2000, Pages 3296-3303

  Giussani, Dino A ^b   Jenkins, Susan L ^a   Winter, James A ^a   Tame, Jennifer D ^a   Nathanielsz, Peter W ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; ESTRADIOL; INTRALIPID; PROGESTERONE;

ANIMAL EXPERIMENT; ARTERIAL BLOOD; ARTICLE; BABOON; CONTROLLED STUDY; ELECTROMYOGRAM; ESTRADIOL BLOOD LEVEL; FEMALE; GESTATIONAL AGE; HORMONAL REGULATION; HORMONE ACTION; HORMONE DETERMINATION; LABOR; MATERNAL BLOOD; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; RADIOIMMUNOASSAY; UTERUS CONTRACTION;

EID: 0034456644     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.9.7677     Document Type: Article

References (50)

1. Sharp increase in free circulating oestrogens immediately before parturition in sheep
2. The mechanism of initiation of parturition in the ewe
3. Regulation of fetoplacental steroidogenesis in rhesus macaques
4. Dally hormonal changes in the maternal, fetal, and amniotic fluid compartments before parturition in a primate species
5. Foward shift in the initiation of the nocturnal estradiol surge in the pregnant babon: Is this the genesis of labor?
6. Serum estradiol in mid and late gestation and estradiol/progesterone ratio in baboons near parturition
7. Endocrine functions of the human fetus and placenta
8. Control of human parturition
9. Plasma estrone, estradiol, estriol, progesterone and 17-hydroxy-progesterone in human pregnancy. I. Normal pregnancy
10. Effect of estradiol and progesterone administration upon the circadian rhythm of oxytocin in the cerebrospinal fluid of rhesus monkeys
11. Estrogen stimulates oxytocin gene expression in human chorio-decidua
12. Influence of estradiol on the secretion of oxytocin and prostaglandin F2a during luteolysis in the ewes
13. Regulation of the estrogen receptor and its mRNA in the ovariectomized sheep myometrium and endometrium: The role of estradiol and progesterone
14. Regulation of oxytocin receptor concentration in rat uterine explants by estrogen and progesterone
15. Oxytocin receptor gene expression in the rat uterus during pregnancy and the estrous cycle and in response to gonadal steroid treatment
16. Gap junction formation in myometrium: Control by estrogens, progesterone, and prostaglandins
17. Increased expression of connexin-43 in the rat myometrium during labor is associated with an increase in the plasma estrogen: Progesterone ratio
18. Regulation of transcripts encoding the myometrial gap junction protein, connexin-43, by estrogen and progesterone
19. Endocrine control of parturition
20. Human term and preterm delivery is preceded by a rise in maternal plasma 17β-estradiol
21. Relation between diurnal changes in peripheral plasma progesterone, cortisol, and estriol in normal women at 30-3134-35 and 38-39 weeks of gestation
22. Serial serum levels of gonadotropins, prolactin and sex steroids in the nonpregnant and pregnant chimapanzees
23. Production of premature delivery in pregnant rhesus monkeys by androstenedione infusion
24. Fetal and maternal endocrine changes during pregnancy and parturition in the rhesus monkey
25. In utero evidence for a functional fetoplacental unit in rhesus monkeys
26. The utilization of circulating dehydroepiandrosterone sulphate for estrogen synthesis during human pregnancy
27. 4-androstenedione infusion on the pregnant rhesus monkey in the last third of gestation: Changes in maternal plasma estradiol concentrations and myometrial contractility
28. 4-Androstenedione-induced, pre-term myometrial concentrations and maternal plasma estradiol and oxytocin concentrations in the 0.8 gestation rhesus monkey
29. Local paracrine effects of estradiol are central to parturition in the rhesus monkey
30. Level of postoperative analgesia is a critical factor in regulation of myometrial contractility after laparotomy in the pregnant baboon: Implications for human fetal surgery
31. Timing of the switch from myometrial contractures to contractions in late gestation pregnant rhesus monkeys recorded by myometrial electromyogram during spontaneous term and androstenedione-induced labor
32. Endocrine changes during 48 hours of food withdrawal in the pregnant rhesus monkey in the last third of gestation
33. Circadian hormonal interactions among the mother, fetus, and amniotic fluid
34. Changes in fetal plasma corticotropin-releasing hormone during androstenedione-induced labor in the rhesus monkey: Lack of an effect on the fetal hypothalamo-pituitary-adrenal axis
35. Increasing aromatase cytochrome P-450 level in human placenta during pregnancy: Studied by immunohistochemistry and enzyme-linked immunosorbent assay
36. Placental steroid hormone biosynthesis in primate pregnancy
37. Circadian patterns and dexamethasone-induced changes in uterine activity in pregnant rhesus monkeys
38. In utero regulation of rhesus monkey fetal adrenals: Effects of dexamethasone, adrenocorticotropin, thyrotropinreleasing hormone, prolactin, human chorionic gonadotropin, and α-melanocyte-stimulating hormone on fetal and maternal plasma steroids
39. Loss of diurnal rhythm in plasma estrone, estradiol, and estriol in women treated with synthetic glucocorticoids at 34 to 35 weeks' gestation
40. Regulation of the primate fetal adrenal cortex
41. Activation of the baboon fetal hypothalamic-pituitary-adrenocortical axis at midgestation by estrogen-induced changes in placental corticosteroid metabolism
42. Insensitivity of near-term fetal sheep to cortisol: Possible relation to the control of parturition
43. Corticotropin-releasing hormone and its receptor distribution in fetal membranes and placenta of the rhesus monkey in late gestation and labor
44. Effect of androstenedione administration on the maternal hypothalamo-pituitary-adreno-placental axis in the pregnant rhesus monkey
45. Studies on the role of oxytocin in late pregnancy in the pregnant rhesus monkey: Plasma concentrations of oxytocin in the maternal circulation throughout the 24-h day and the effect of the synthetic oxytocin antagonist [1-β-Mpa(β-(CH2)5)1,(Me(Tyr2, Orn8] oxytocin on spontaneous nocturnal myometrial contractions
46. Correlation of nocturnal increase in plasma oxytocin with a decrease in plasma estradiol/progesterone ratio in late pregnancy
47. Do tocolytic agents stop preterm labor? A critical and comprehensive review of efficacy and safety
48. The oxytocin antagonist atosiban prevents androstenedione-induced myometrial contractions in the chronically instrumented, pregnant rhesus monkey
49. Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70
50. Increased myometrial (MYO) heat shock proteins (HSP's) may oppose the action of progesterone (P) during labor in primates