Epstein-barr virus-positive undifferentiated thymic carcinoma in a 12-year-old white girl

American Journal of Pediatric Hematology/Oncology

Volumn 22, Issue 2, 2000, Pages 162-166

  Stéphan, Jean Louis ^a   Galambrun, Claire ^a   Boucheron, Simone ^a   Varlet, F ^a   Delabesse, E ^b   MacIntyre, E ^b  

^a HÔPITAL NORD   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Children; Epstein Barr virus; Undifferentiated thymic carcinoma

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; ETOPOSIDE; IFOSFAMIDE; IMMUNOGLOBULIN A; VIRUS DNA; VIRUS RNA;

ANTIBODY TITER; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CASE REPORT; CHILD; COMPUTER ASSISTED TOMOGRAPHY; EPISOME; EPSTEIN BARR VIRUS; FATALITY; FEMALE; HUMAN; IN SITU HYBRIDIZATION; MEDIASTINUM CANCER; METASTASIS; PRIORITY JOURNAL; THORAX RADIOGRAPHY; THYMUS CANCER; UNDIFFERENTIATED CARCINOMA; VIRUS CARCINOGENESIS; VIRUS INFECTION;

CARCINOMA; CHILD; DNA, VIRAL; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRUS 4, HUMAN; HUMANS; RNA, VIRAL; THYMOMA; THYMUS NEOPLASMS;

EID: 0034456396     PISSN: 01928562     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-200003000-00016     Document Type: Article

References (19)

1. Ramon y Cajal S, Suster S. Primary thymic epithelial neoplasms in children. Am J Surg Pathol 1991;5: 466-74.
2. Pathmanathan R, Prasad U, Sadler R, et al. Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma. N Engl J Med 1995;333: 693-8.
3. Birkenbach M, Tong X, Bradbury LE, et al. Characterization of an Epstein-Barr virus receptor on human epithelial cells. J Exp Med 1992;176: 1405-14.
4. Pratt CB, Douglas EC. Management of the less common cancers in childhood. In: Pizzo PA, Poplack DG, eds. Principles and Practice of Pediatric Oncology, 3rd ed. Philadelphia, Lippincott-Raven, 1997: 977-1003.
5. Spigland N, Di Lorenzo M, Youssef S, et al. Malignant thymoma in children: A 20 year review. J Pediatr Surg 1990;25: 1143-6.
6. Nonoyama M, Huang CH, Pagano JS. DNA of Epstein Barr virus detected in tissue of Burkitt’s lymphoma and nasopharyngeal carcinoma. Proc Natl Acad Sci USA 1973;70: 3265-68.
7. McClain KL, Leach CT, Jenson HB, et al. Association of Epstein-Barr virus with leiomyosarcomas in children with AIDS. N Engl J Med 1995;332: 12-8.
8. Chan JK, Yip TT, Tsang WY, et al. Specific association of Epstein-Barr virus with lymphoepithelial carcinoma among tumors and tumorlike lesions of the salivary gland. Arch Pathol Lab Med 1994;118: 994-7.
9. Iezzoni JC, Gaffey MJ, Weiss LM. The role of Epstein-Barr virus in lymphoepithelioma-like carcinomas. Am J Clin Pathol 1995;103: 308-15.
10. Wu TC, Kuo TT. Study of Epstein-Barr virus early RNA 1 (EBER1) expression by in situ hybridization in thymic epithelial tumors of Chinese patients in Taiwan. Hum Pathol 1993;3: 235-8.
11. Leyvraz S, Henle W, Chahinian AP, et al. Association of Epstein-Barr virus with thymic carcinoma. N Engl J Med 1985;312: 1296-9.
12. McGuire LJ, Huang DP, Teoh R, et al. Epstein-Barr virus genome in thymoma and thymic lymphoid hyperplasia. Am J Pathol 1988;3: 385-90.
13. Dimery IW, Lee JS, Blick M, et al. Association of the Epstein-Barr virus with lymphoepithelioma of the thymus. Cancer 1988;61: 2475-80.
14. Fujii T, Kawai T, Saito K, et al. EBER-1 expression in thymic carcinoma. Acta Pathol Jpn 1993;3: 107-10.
15. Brooks L, Yao QY, Rickinson AB, et al. Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts. J Virol 1992;66: 2689-97.
16. Klein G. Epstein-Barr virus strategy in normal and neoplastic B cells. Cell 1994;77: 791-3.
17. Sixbey JW, Yao QY. Immunoglobulin A-induced shift of Epstein-Barr virus tissue tropism. Science 1992;255: 1578-80.
18. Ilhan I, Kutluk T, Gogus S, et al. Hypertrophic pulmonary osteoarthropathy in a child with thymic carcinoma: an unusual presentation in childhood. Med Pediatr Oncol 1994;23: 140-3.
19. Niehues T, Harms D, Jurgens H, et al. Treatment of pediatric malignant thymoma: Long-term remission in a 14-year-old boy with EBV-associated thymic carcinoma by aggressive, combined modality treatment. Med Pediatr Oncol 1996;26: 419-24.