Germline mutations of the APC gene in patients with familial adenomatous polyposis-associated thyroid carcinoma: Results from a European Cooperative Study

Journal of Clinical Endocrinology and Metabolism

Volumn 85, Issue 1, 2000, Pages 286-292

  Cetta, F ^a   Montalto, G ^a   Gori, M ^a   Curia, M C ^b   Cama, A ^b   Olschwang, S ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c Fondation Jean Dausset   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; DISEASE ASSOCIATION; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; MALE; PAPILLARY CARCINOMA; PIGMENT EPITHELIUM; PRIORITY JOURNAL; SCHOOL CHILD; THYROID CARCINOMA; THYROID NODULE;

ADENOMATOUS POLYPOSIS COLI; ADOLESCENT; ADULT; CARCINOMA, PAPILLARY; CHILD; CHROMOSOME MAPPING; EUROPE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MUTATION; PHENOTYPE; SEQUENCE DELETION; THYROID GLAND; THYROID NEOPLASMS;

EID: 0034456384     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.85.1.286     Document Type: Article

References (56)

1. Lesson from hereditary colorectal cancer
2. Molecular basis of thyroid cancer
3. Familial nonmedullary thyroid carcinoma: The case for genetic susceptibility
4. Familial nonmedullary thyroid carcinomas: A heterogeneous syndrome with different natural history and variable long-term prognosis
5. Identification of FAP locus genes from chromosome 5q21
6. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
7. Identification and characterization of the familial adenomatous polyposis coli gene
8. Multiplex PCR analysis and genotype-phenotype correlations of frequent APC mutation
9. A novel deletion in exon 15 of the adenomatous polyposis coli gene in an Italian kindred
10. Multiple primary malignancy arising in the rectum, brain and thyroid. Report of a case
11. Association of thyroid carcinoma with Gardner's syndrome in siblings
12. Papillary thyroid carcinoma in Danish patients with familial adenomatous polyposis
13. Thyroid carcinoma in two sisters with familial adenomatous polyposis of the colon
14. Sisters with familial adenomatous polyposis affected with thyroid carcinoma, desmoid tumor and duodenal polyposis
15. Thyroid cancer in patients with familial adenomatous polyposis
16. Familial adenomatous polyposis-associated thyroid cancer
17. The impact of familial adenomatous polyposis on the tumorigenesis and mortality at the several organs
18. Is screening for thyroid carcinoma indicated in familial adenomatous polyposis?
19. Adenomatous polyposis: An association with carcinoma of the thyroid
20. Increased risk of thyroid and pancreatic carcinoma in familial adenomatous polyposis
21. Gardner's syndrome and thyroid cancer a case report and review of the literature
22. Papillary thyroid carcinoma in three siblings with familial adenomatous polyposis
23. Thyroid carcinoma associated with familial adenomatous polyposis
24. The RET/PTC oncogene is activated in familial adenomatous polyposis-associated thyroid papillary carcinomas
25. Familial adenomatous polyposis (Gardner's syndrome) and thyroid carcinoma. A case report and review of the literature
26. Familial adenomatous polyposis associated thyroid carcinoma: A distinct type of follicular cell neoplasm
27. Polypose rectolique familial, syndrome de Gardner et cancer thyroidien: Estude de deux cas
28. Papillary carcinoma of the thyroid and familial polyposis coli
29. Gardner's syndrome with duodenal adenomas, gastric adenomyoma and thyroid papillary-follicular adenocarcinoma
30. Association between thyroid cancer of the cribriform variant and familial adenomatous polyposis
31. Coexistence of somatic and germ-line mutations of APC gene in desmoid tumors from patients with familial adenomatous polyposis
32. Hyalinizing trabecular carcinoma of the thyroid gland
33. Polypose adénomatose famlliale et cancer de la thyroide
34. Identification of the APC gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis
35. Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype
36. Hepatoblastoma and APC gene mutation in familial adenomatous polyposis
37. Childhood hepatocellular tumours in familial adenomatous polyposis
38. Screening for germ-line mutations in familial adenomatous polyposis patients: 61 new patients and a summary of 150 unrelated patients
39. Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients
40. Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene
41. APC gene: Database of germline and somatic mutations in human tumors and cell lines
42. Familial adenomatous polyposis: Desmoid tumours and lack of ophtalmic lesions (CHRPE) associated with APC mutations beyond codon 1444
43. Novel mutations and in-activation of both alleles of the APC gene in desmoid tumors
44. Identical APC exon 15 mutations result in a variable phenotype in familial adenomatous polyposis
45. Phenotypic variability of familial adenomatous polyposis in 11 unrelated families with identical APC gene mutation
46. Familial segregation in the occurrence and severity of periampullary neoplasms in familial adenomatous polyposis
47. Evidence against involvement of APC mutation in papillary thyroid carcinoma
48. Mutations of the adenomatous polyposis coli gene in sporadic thyroid neoplasms
49. Analysis of adenomatous polyposis coli gene in thyroid tumors
50. Germ-line APC mutations in patients with familial adenomatous polyposis associated with thyroid carcinoma. Result from a European collaborative study
51. The wild type APC allele is not lost in FAP associated thyroid tumors, showing activation of the chimeric oncogene ret-PTC
52. Comment on Carney complex and related syndromes and their genetic loci
53. Thyroid cancer and the Chernobyl accident. Are long-term and long distance side-effects of fall-out radiation greater than estimated?
54. Genetic alteration in thyroid carcinoma associated with familial adenomatous polyposis: Clinical implications and suggestions for early detection
55. Genetics and clinicopathological findings in thyroid carcinomas associated with familial adenoamtous polyposis