Clinical pharmacology of the fluoroquinolones: Studies in human dynamic/kinetic models

Clinical Infectious Diseases

Volumn 31, Issue SUPPL. 2, 2000, Pages

  Schentag, J J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANTIBIOTIC SENSITIVITY; AREA UNDER THE CURVE; CONFERENCE PAPER; DOSE CALCULATION; DRUG EFFICACY; HUMAN; MINIMUM INHIBITORY CONCENTRATION; PHARMACODYNAMICS; PNEUMONIA; PRIORITY JOURNAL;

ANTI-INFECTIVE AGENTS; CROSS INFECTION; DRUG RESISTANCE, MICROBIAL; FLUOROQUINOLONES; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; MICROBIAL SENSITIVITY TESTS; MODELS, BIOLOGICAL; PNEUMONIA, BACTERIAL;

EID: 0034453916     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/314059     Document Type: Conference Paper

References (21)

1. Pharmacokinetics, safety, and tolerability of ascending single doses of moxifloxacin, a new 8-methoxy quinolone, administered to healthy subjects
2. Expanded activity and utility of the new fluoroquinolones: A review
3. Antibiotic dosing - Does one size fit all?
4. Mathematical examination of dual individualization principles. I. Relationships between AUC above MIC and area under the inhibitory curve for cefmenoxime, ciprofloxacin, and tobramycin
5. Pharmacokinetics and pharmacodynamics of fluoroquinolones
6. Two pharmacodynamic models for assessing the efficacy of amoxicillin-clavulanate against experimental respiratory tract infections caused by strains of Streptococcus pneumoniae
7. Comparison of pharmacodynamics of azithromycin and erythromycin in vitro and in vivo
8. Pharmacodynamic activities of ciprofloxacin and sparfloxacin in a murine pneumococcal pneumonia model: Relevance for drug efficacy
9. Pharmacodynamics of fluoroquinolones in experimental models of endocarditis
10. Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men
11. The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome: Focus on antibacterial agents
12. Pharmacodynamics and pharmacokinetics of antibiotics with special reference to the fluoroquinolones
13. Relevance of pharmacokinetics and pharmacodynamics in the selection of antibiotics for respiratory tract infections
14. Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients
15. Pharmacokinetics and pharmacodynamics of oral grepafloxacin in patients with acute bacterial exacerbations of chronic bronchitis
16. Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy
17. Pharmacodynamics of levofloxacin: A new paradigm for early clinical trials
18. Use of serum ultrafiltrate in the serum bacteridical test
19. Mathematical examination of dual individualization principles (II): The rate of bacterial eradication at the same area under the inhibitory curve is more rapid for ciprofloxacin than for cefmenoxime
20. Clinical significance of antibiotic tissue penetration