Proteasome inhibition suppresses cisplatin-dependent ERCC-1 mRNA expression in human ovarian tumor cells

Research Communications in Molecular Pathology and Pharmacology

Volumn 107, Issue 5-6, 2000, Pages 387-396

  Li, Q Q ^a   Ding, L ^a   Reed, E ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DNA; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; LACTACYSTIN; MESSENGER RNA; N ACETYLLEUCYLLEUCYLNORLEUCINAL; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN RAD6; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CELL KILLING; CONTROLLED STUDY; DNA ADDUCT; DRUG CYTOTOXICITY; DRUG DNA BINDING; ENZYME INHIBITION; EXCISION REPAIR; FEMALE; HUMAN; HUMAN CELL; NORTHERN BLOTTING; OVARY CARCINOMA; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANTI-BACTERIAL AGENTS; CISPLATIN; CYSTEINE ENDOPEPTIDASES; DNA REPAIR; DNA-BINDING PROTEINS; DRUG RESISTANCE, NEOPLASM; ENDONUCLEASES; FEMALE; HUMANS; LACTAMS; MULTIENZYME COMPLEXES; OVARIAN NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0034426310     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Nucleotide excision repair in vitro and in normal/abnormal human cells
2. Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities
3. The proteasome
4. The proteasome: Paradigm of self compartmentalizing protease
5. Characterization of a cis-diamminedichloroplatinum (II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues
6. Effects of interleukin-1α on DNA repair in human ovarian carcinoma (NIH:OVCAR-3) cells: Implications in the mechanism of sensitization of cis-diamminedichloroplatinum (II)
7. The ubiquitin-proteasome pathway: On protein death and cell life
8. ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients
9. Messenger RNA levels of XPA and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy
10. Mechanistic studies on the inactivation of the proteasome by lactacystin in cultured cells
11. Inhibition of proteasome activities and subunit-specific amino-acid terminal threonine modification by lactacystin
12. Transcription factor II H: A key player in the cellular response to DNA damage
13. Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6
14. Specific association between the human DNA repair proteins XPA and ERCC1
15. Interferon-γ induced increases in intracellular cathepsin B activity in THP-1 cells are dependent on RNA transcription
16. Effect of interleukin-1α and tumor necrosis factor-α on cisplatin-induced ERCC-1 mRNA expression in a human ovarian carcinoma cell line
17. Interferon-γ induces cathepsin B expression in a human macrophage-like cell line by increasing both transcription and mRNA stability
18. Cisplatin and phorbol ester independently induce ERCC-1 protein in human ovarian tumor cells
19. Endotoxin induces increased intracellular cathepsin B activity in THP-1 cells
20. Cisplatin induction of ERCC-1 mRNA expression in A2780/CP70 human ovarian cancer cells
21. Modulation of ERCC-1 messenger RNA expression by pharmacological agents in human ovarian carcinoma cells
22. Association between the level of ERCC-1 expression and the repair of cisplatin-induced DNA damage in human ovarian cancer cells
23. Effects of histone acetylation, ubiquitination and variants on nucleosome stability
24. Mice with DNA repair gene (ERCC1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning
25. ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy
26. Rapid deubiquitination of nucleosomal histones in human tumor cells caused by proteasome inhibitors and stress response inducers: Effects on replication, transcription, translation, and the cellular stress response
27. Blocked repair of cisplatin-induced DNA damage and increased cisplatin cytotoxicity associated with nucleosomal histone deubiquitination
28. Formation of a ternary complex by human XPA, ERCC1, and ERCC4 (XPF) excision repair proteins
29. Nucleotide excision repair: From E. coli to man
30. Cisplatin and related drugs
31. The multicatalytic and 26S proteases
32. Nucleotide excision repair and anti-cancer chemotherapy
33. Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy
34. Proteasomes: Structure and biology
35. Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10
36. Genomic characterization of the human DNA excision repair gene ERCC-1
37. What happens to nucleosomes during transcription?
38. Sensitization by interleukin-1α of carboplatinum anti-tumor activity against human ovarian (NIH:OVCAR-3) carcinoma cells in vitro and in vivo
39. DNA damage recognition during nucleotide excision repair in mammalian cells