Two New Indole Alkaloids from Evodia rutaecarpa

Chinese Chemical Letters

Volumn 11, Issue 2, 2000, Pages 127-128

  Zuo, Guo Ying ^a,b   Yang, Xiao Sheng ^a   Hao, Xiao Jiang ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b Hospital of Kunming   (China)

Author keywords

Evodia rutaecarpa (Juss.)Benth; Indolinone alkaloids; Rutaceae; Wuchuyuamides

Indexed keywords

EID: 0034424592     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Y. Q. Tang, X. Z. Feng, L. Huang, Phytochemistry, 1996, 43(3), 71.
2. Ian A. Southewell, Phytochemistry, 1981, 20 (6), 1448.
3. N. Shoji, A. Umeyama, A. Iuchi et al, J. Nat.Prod., 1989, 52 (5), 1160.
4. H. Fritz., T. Winkler, Helv. Chem. Acta, 1976, 59, 903.
5. 5N of 2, δ in ppm). Compound 1: δ 11.65 (1H, s, 1-N-H), 4.72, 4.84 (each 1H, m, H-5), 2.81, 2.92 (each 1H, m, H-6), 5.25 (1H, br., 7-O-H), 7.79 (1H, d, J=7.2Hz, H-9), 7.04 (1H, t, J=7.4Hz, H-10), 7.21 (1H,m, H-11), 6.97 (1H, d, J=8.0Hz, H-12), 7.09 (1H, d, J=8.4Hz, H-16), 7.58 (1H, m, H-17), 7.15 (1H, t, J=7.6Hz, H-18), 8.27 (1H, dd, J=6.4,1.6Hz, H-19), 3.40 (3H, s, H-22); Compound 2: δ 4.18, 4.42 (each 1H, m, H-5), 2.26, 2.50 (each 1H, m, H-6), 3.54 (1H, t, J=6.2Hz, H-7), 7.62 (1H, m, H-9), 6.88 (1H, t, J=7.5Hz, H-10), 7.21 (1H, m, H-11), 6.81 (1H, d, J=7.7Hz, H-12), 7.07 (1H, d, J=7.6Hz, H-16), 7.31 (1H, d, J=7.4Hz, H-17), 7.11 (1H, d, J=8.3Hz, H-18), 8.14 (1H, dd, J=6.2,1.6. H-19), 3.51 (3H, s, H-22).
6. 13CNMR data of compounds 1 and 2. Compound 1: 180.6 (s, C-2), 151.0 (s, C-3), 37.7 (t, C-5), 36.4 (t, C-6), 75.9 (s, C-7), 133.4 (s, C-8), 124.9 (d, C-9), 122.3 (d, C-10), 129.5 (d, C-11), 110.4 (d, C-12), 143.0 (s, C-13), 141.0 (s, C-15), 114.3 (d, C-16), 135.2 (d, C-17), 122.8 (d, C-18), 128.7 (d, C-19), 116.1 (s, C-20), 161.6 (s,C-21), 30.6 (q, C-22); Compound 2: 179.4 (s, C-2), 150.8 (s, C-3), 39.2 (t, C-5), 28.0 (t, C-6), 44.2 (d, C-7), 129.1 (s, C-8). 124.0 (d, C-9), 122.1 (d, C-10), 127.8 (d, C-11), 109.6 (d, C-12), 141.6 (s, C-13), 140.5 (s, C-15), 113.4 (d, C-16), 134.9 (d, C-17), 122.8 (d,C-18), 128.9 (d, C-19), 115.5 (s, C-20), 161.7 (s, C-21), 30.6 (q, C-22).