Et2AlCl-Mediated Reaction of α-4(20)-Epoxy-5α-hydroxy Taxinine B

Chinese Chemical Letters

Volumn 11, Issue 3, 2000, Pages 199-202

  Cheng, Qian ^a   Oritani, Takayuki ^a   Horiguchi, Tohru ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Antitumour compounds; Diethylaluminum chloride; Epoxide; Taxoides

Indexed keywords

EID: 0034387320     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. M.C. Wani, H. L. Taylor, M. E. Wall, et al., J. Am. Chem. Soc., 1971, 93, 2325.
2. a) F. A. Holmes, A. P. Kudelka, J. J. Karanagh, et al., Taxane Anticancer Agents: Basic Science and Current Status, G. I. Georg, T. T. Chen, I. Ojima, et al., Ed. American Chemical Society: Washington, DC, 1994, pp. 31.
3. b) S. G. Arbuck, B. A. Blaylok, In Taxol: Science and Applications, M. Suffness Ed.CRC Press Inc., Boca raton, FL, 1995, pp. 379.
4. a) D. G. I. Kingston, A. A. Molinero, J. M. Rimoldi, Prog. Chem. Org. Nat. Prod., 1993, 61,1.
5. b) M. Suffness, Annu. Rep. Med. Chem., 1993, 28, 305; G. I. Georg, S. M. Ali, J Zymumt, et al.,. Expert Opin. Ther. Pat., 1994, 12, 222.
6. b) M. Suffness, Annu. Rep. Med. Chem., 1993, 28, 305; G. I. Georg, S. M. Ali, J Zymumt, et al.,. Expert Opin. Ther. Pat., 1994, 12, 222.
7. D. G. I. Kingston, M. D. Chordia, G. J. Prakash, et al., J. Org. Chem., 1999, 64, 1814.
8. a) S. H. Chen, S. Huang, Q. Gao, et al., J. Org. Chem., 1994, 59, 1475.
9. b) A. G. Chaudhary, M. D. Chordia, D. G. I. Kingston, J. Org. Chem., 1995, 60, 3260.
10. C. Z. Yu, Z. Y. Liu, Tetrahedron Lett., 1997, 38, 4133.
11. M. C. Woods, H.C. Chiang, Y. Nakadaira, et al., J. Am. Chem. Soc., 1968, 522.
12. Y. Bathini, R. G. Micetich, M. Daneshtalab, Synth. Commun., 1994, 24, 1513.
13. a) Q. Cheng, T. Oritani, T. Horiguchi, Tetrahedron, 1999, 55, 12099.
14. b) H. Hosoyama, H. Shigemori, Y. In, et al., Tetrahedron 1998, 54, 2521.
15. +) 569.2595, found 569.2567 (Δ1.2 mmu).
16. 3-19. However, such correlations were not observed in NOESY experiment of 2.