Puromycin-induced Lipid Peroxidation in the Cochlea of ApoeE Knockout Mice

Acta Oto-Laryngologica

Volumn 120, Issue 543, 2000, Pages 102-104

  Aarnisalo, Antti A ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; AMINONUCLEOSIDE; ANTIBODY; ANTILIPEMIC AGENT; APOLIPOPROTEIN E; LIPID; MALONALDEHYDE; PROBUCOL; PUROMYCIN; HYPOCHOLESTEROLEMIC AGENT; PROTEIN SYNTHESIS INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; CHOLESTEROL BLOOD LEVEL; COCHLEA; CONFERENCE PAPER; CONTROLLED STUDY; IMMUNOREACTIVITY; KIDNEY INJURY; KNOCKOUT MOUSE; LIPID PEROXIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRIA VASCULARIS; ANIMAL; ARTICLE; DRUG EFFECT; HAIR CELL; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

ANIMALS; ANTICHOLESTEREMIC AGENTS; APOLIPOPROTEINS E; COCHLEA; HAIR CELLS; LIPID PEROXIDATION; MICE; MICE, KNOCKOUT; PROBUCOL; PROTEIN SYNTHESIS INHIBITORS; PUROMYCIN; STRIA VASCULARIS;

EID: 0034353541     PISSN: 00016489     EISSN: 16512251     Source Type: Journal    
DOI: 10.1080/000164800454116     Document Type: Article

References (12)

1. Plump AS, Smith JD, Hayek T, et al. Severe hyperc-holesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 1992; 71: 343 – 53.
2. Yamane H, Nakai Y. Inner ear damage due to lipoid nephrosis. Eur Arch Otorhinolaryngol 1993; 250: 177 – 81.
3. Porter NA, Caldwell SE, Mills KA. Mechanisms of free radical oxidation of unsaturated lipids. Lipids 1995; 30: 277 – 90.
4. Mattson MP. Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adap-tive plasticity. Trends Neurosci 1998; 21: 53 – 7.
5. Quirk WS, Bhagyalakshmi GS, Schwimmer CL, Seid-man MD. Lipid peroxidation inhibitor attenuates noise-induced temporary threshold shifts. Hear Res 1994; 74: 217 – 20.
6. Demopoulos HB, Flamm ES, Pietronigro DD, Selig-man ML. The free radical pathology and the microcir-culation in the major central nervous system disorders. Acta Physiol Scand 1980; Suppl 492: 91 – 119.
7. Seidman MD, Quirk WS, Nuttall AL, Schweitzer VG. The protective effects of allopurinol and superoxide dismutase-polyethylene glycol on ischemic and reperfu-sion induced cochlear damage. Otolaryngol Head Neck Surgery 1991; 105: 457 – 62.
8. Hall ED, Yonkers PA, Horan Kt, Braughler JM. Correlation between attenuation of posttraumatic spinal cord ischemia and preservation of tissue vitamin E by the 21-aminosteroid U74006F: evidence for an in vivo antioxidant mechanism. J Neurotrauma 1989; 3: 169.
9. Magil A. Inhibition of progression of chronic puromycin aminonucleoside nephrosis by probucol, an antioxidant. J Am Soc Nephrol 1996; 7: 2340 – 7.
10. Montine TJ, Amarnath V, Martin ME, Strittmetter WJ, Graham DG. E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. Am J Pathol 1996; 148: 89 – 93.
11. Ford MS, Nie Z, Whitworth C, Rybak LP, Ramkumar V. Up-regulation of adenosine receptors in the cochlea by cisplatin. Hear Res 1997; 111: 143 – 52.
12. Neale TJ, Ullrich R, Ojha P, Poczewski H, Verhoeven AJ, Kerjaschki D. Reactive oxygen species and neu-trophil respiratory bursts cytochrome b558 are pro-duced by kidney glomerular cells in passive Heymann nephritis. Proc Natl Acad Sci USA 1993; 90: 3645 – 9.