Tetrandrine inhibits reward rectifying potassium current in cultured bovine aortic endothelial cells

Acta Pharmacologica Sinica

Volumn 21, Issue 12, 2000, Pages 1115-1118

  Liu, Wan Bin ^c   Liu, Gou Qing ^a   Xiao, Hang ^b   Mao, Xia ^b   Shi, Yun ^b   Wu, Jian Ping ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c NONE

Author keywords

Patch clamp techniques; Potassium channels; Tetrandrine; Vascular endothelium

Indexed keywords

TETRANDRINE; ALKALOID; BENZYLISOQUINOLINE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL;

ANIMAL CELL; AORTA; ARTICLE; CATTLE; CONTROLLED STUDY; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; VASCULAR ENDOTHELIUM; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT;

ALKALOIDS; ANIMALS; AORTA; BENZYLISOQUINOLINES; CALCIUM CHANNEL BLOCKERS; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS;

EID: 0034353178     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Tetrandrine: A novel calcium channel antagonist inhibits type I calcium channels in neuroblastoma cells
2. Tetrandrine inhibits both T and L calcium channel currents in ventricular cells
3. Tetrandrine is not a selective calcium channel blocker in vascular smooth muscle
4. Structure and hypotensive activity relationships of Tetrandrine derivatives in stroke-prone spontaneously hypertensive rats
5. Comparison of effects of Tetrandrine on ionic channels of isolated rat neurohypophysial terminals and Y1 mouse adrenocortical tumor cells
6. Ion channels in vascular endothelium
7. + pump activity modulate resting and bradykinin-stimulated changes in cytosolic free calcium in cultured endothelial cells from bovine atria
8. Bradykinin-induced potassium current in cultured bovine aortic endothelial cells
9. Comparison of tissue-cultured bovine endothelial cells from aorta and daphenous vein in vitro
10. Modulation of cell membrane potential in cultured vascular endothelium
11. Intrinsic gating of inward rectifying potassium current in bovine pulmonary artery endothelial cells in the presence or absence of internal magnesium
12. Mechanisms of action of 7-O-ethyl Tet in isolated vascular smooth muscle of rat aorta
13. ++ antagonist: Effects and mechanisms of action in vascular smooth muscle cells
14. Effects of dauricine on potassium currents in guinea pig ventricular myocytes
15. Specific interaction between Tet and Quillaja saponins in promotion permeabilization of plasma membrane in human leukemic HL-60 cells