Arg60 Leu mutation in the first cytoplasmic loop of the platelet thromboxane A2 receptor is not essential for mediating inhibitory coupling between the receptor and adenylyl cyclase

Acta Haematologica

Volumn 104, Issue 2-3, 2000, Pages 95-98

  Fuse, Ichiro ^a   Higuchi, Wataru ^a   Aizawa, Yoshifusa ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

Bleeding disorder unresponsive to TXA2; Cyclic AMP; Inhibitory coupling between platelet thomboxane A2 receptor and adenylyl cyclase; Platelet thromboxane A2 receptor

Indexed keywords

ADENYLATE CYCLASE; ARGININE; CYCLIC AMP; LEUCINE; PHOSPHOLIPASE C; THROMBOXANE A2 RECEPTOR; 9,11 EPITHIO 11,12 METHANOTHROMBOXANE A2; DRUG DERIVATIVE; FORSKOLIN; PEPTIDE FRAGMENT; PROSTAGLANDIN E1; THROMBOXANE A2; THROMBOXANE RECEPTOR;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; BLEEDING DISORDER; CYTOPLASM; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THROMBOCYTE; BLOOD; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MIDDLE AGED; MISSENSE MUTATION; PROTEIN TERTIARY STRUCTURE; THROMBOCYTE DISORDER;

ADENYLATE CYCLASE; ADULT; ALPROSTADIL; AMINO ACID SUBSTITUTION; ARGININE; BLOOD PLATELET DISORDERS; BLOOD PLATELETS; CYCLIC AMP; CYTOPLASM; FEMALE; FORSKOLIN; HUMANS; LEUCINE; MALE; MIDDLE AGED; MUTATION, MISSENSE; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THROMBOXANE; THROMBOXANE A2;

EID: 0034352484     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000039758     Document Type: Article

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