Stimulated secretion of pituitary hormones in normal humans: a novel direct assessment from blood concentrations

Annals of Biomedical Engineering

Volumn 28, Issue 9, 2000, Pages 1136-1145

  De Nicolao, Giuseppe ^a   Liberati, Diego ^b   Sartorio, Alessandro ^c  

^a UNIVERSITY OF PAVIA   (Italy)

^b CNR   (Italy)

^c ISTITUTO AUXOLOGICO ITALIANO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; DIAGNOSIS; HORMONES; PATHOLOGY; PHYSIOLOGY;

BLOOD CONCENTRATION; DECONVOLUTION ANALYSIS; FOLLICLE STIMULATING HORMONE; STIMULATED PITUITARY SECRETION;

ENDOCRINOLOGY;

CORTICOTROPIN RELEASING FACTOR; GONADORELIN; HYPOPHYSIS HORMONE; PROTIRELIN;

ADOLESCENT; ADULT; AGED; ARTICLE; BIOLOGICAL MODEL; BIOMEDICAL ENGINEERING; BLOOD; DRUG EFFECT; FEMALE; HUMAN; HYPOPHYSIS; KINETICS; MALE; MIDDLE AGED; SECRETION; VALIDATION STUDY;

ADOLESCENT; ADULT; AGED; BIOMEDICAL ENGINEERING; CORTICOTROPIN-RELEASING HORMONE; FEMALE; GONADOTROPIN-RELEASING HORMONE; HUMANS; KINETICS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PITUITARY GLAND; PITUITARY HORMONES; THYROTROPIN-RELEASING HORMONE;

EID: 0034352215     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.1312185     Document Type: Article

References (21)

1. Charter, M. K., and S. F. Gull. Maximum entropy and drug absorption. J. Pharmacokin. Biopharm. 19:497-520, 1991.
2. De Nicolao, G., and D. Liberati. Linear and nonlinear techniques for the deconvolution of hormone time-series. IEEE Trans. Biomed. Eng. 40:440-455, 1993.
3. De Nicolao, G., D. Liberati, and A. Sartorio. Deconvolution of infrequently sampled data for the estimation of growth hormone secretion. IEEE Trans. Biomed. Eng. 42:678-687, 1995.
4. De Nicolao, G., D. Liberati, J. D. Veldhuis, and A. Sartorio. LH and FSH secretory responses to GnRH in normal individuals: A nonparametric deconvolution approach. Eur. J. Endocrinol. 141:246-256, 1999.
5. De Nicolao, G., G. Sparacino, and C. Cobelli. Nonparametric input estimation in physiological systems: Problems, methods, and case studies. Automatica 33:851-870, 1997.
6. Groth, T., S. Rosberg, and K. Albertsson-Wikland. Estimation of growth hormone secretory patterns in children with use of a numerical deconvolution technique experimental design with use of computer simulation. Horm Res. 42:245-252, 1994.
7. Hindmarsh, P. C., D. R. Matthews, C. E. Brain, P. J. Pringle, L. Di Silvio, A. B. Kurtz, and C. G. D. Brook. The half-life of exogenous growth hormone after suppression of endogenous growth hormone secretion with somatostatin. Clin. Endocrinol. 30:443-450, 1989.
8. Odell, W. D., R. D. Utiger, J. F. Wilber, and P. G. Condliffe. Estimation of the secretion rate of Thyrotropin in man. J. Clin. Invest. 6:53-959, 1967.
9. Phillips, D. L.. A technique for the numerical solution of certain integral equations of the first kind. J. Assoc. Comput. Mach. 9:97-101, 1962.
10. Reichlin, S. Neuroendocrinology. In: Williams Textbook of Endocrinology, 9th ed. edited by J. D. Wilson, D. W. Foster, H. M. Kronenberg, and P. R. Larsen. Philadelphia: W. B. Saunders, 1998, pp. 165-248.
11. Sartorio, A., G. De Nicolao, G. Pizzini, and D. Liberati. Non-parametric deconvolution provides an objective assessment of GH responsiveness to GH-releasing stimuli in normal subjects. Clin. Endocrinol. 46:387-395, 1997.
12. Sartorio, A., A. Spada, F. Morabito, and G. Faglia. Different responsiveness to repeated GHRH administration in normal children and adults. J. Endocrinol. Invest. 11:727-729, 1988.
13. Sparacino, G., and C. Cobelli. A stochastic deconvolution method to reconstruct insulin secretion rate after a glucose stimulus. IEEE Trans. Biomed. Eng. 43:512-529, 1996.
14. Sparacino, G., and C. Cobelli. Impulse response model in reconstruction of insulin secretion by deconvolution: role of input design in the identification experiment. Ann. Biomed. Eng. 25:398-416, 1997.
15. Tikhonov, A. N., and V. Y. Arsenin. In: Solutions of Ill-Posed Problems. Washington: Winston/Wiley, 1977.
16. Urban, R. J., V. Padmanabhan, I. Beitins, and J. D. Veldhuis. Metabolic clearance of human follicle-stimulating hormone assessed by radioimmunoassay, immunoradiometric assay, and in vitro Sertoli cell bioassay. J. Clin. Endocrinol Metab. 73:818-823, 1991.
17. Veldhuis, J. D.. How does one get at glandular secretion, when only hormone concentrations are measured? Clin. Endocrinol. 46:397-400, 1997.
18. Veldhuis, J. D., M. L. Carlson, and M. L. Johnson. The pituitary gland secretes in bursts: Appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. Proc. Natl. Acad. Sci. U.S.A. 4:7686-7690, 1987.
19. Veldhuis, J. D., F. Fraioli, A. D. Rogol, and M. L. Dufau. Metabolic clearance of biologically active luteirizing hormone in man. J. Clin. Invest. 77:1122-1128, 1985.
20. Veldhuis, J. D., J. Moorman, and M. L. Johnson. Deconvolution analysis of neuroendocrine data: waveform-specific and waveform-independent methods and applications. Methods in Neurosciences 20:279-325, 1994.
21. Verotta, D.. Estimation and model selection in constrained deconvolution. Ann. Biomed. Eng. 21:605-620, 1993.