Combinatorial library design for diversity, cost efficiency, and drug-like character

Journal of Molecular Graphics and Modelling

Volumn 18, Issue 4-5, 2000, Pages 427-437

  Brown, Robert D ^a   Hassan, Moises ^a   Waldman, Marvin ^a  

^a ACCELRYS INC   (United States)

Author keywords

Diversity; Drug likeness; Library design; Lipinski's Rules; Similarity

Indexed keywords

BIOCHEMISTRY; COMPUTER SOFTWARE; DRUG DOSAGE; LIBRARIES; MOLECULES; COMBINATORIAL MATHEMATICS; COMPUTER SYSTEMS PROGRAMMING; COST EFFECTIVENESS; DATABASE SYSTEMS;

COMBINATORIAL LIBRARY DESIGN; COMBINATORIAL LIBRARIES; MOLECULAR DIVERSITY;

DRUG PRODUCTS; MOLECULAR DYNAMICS;

REAGENT;

ARTICLE; COMBINATORIAL CHEMISTRY; COMPUTER AIDED DESIGN; COST CONTROL; DRUG ACTIVITY; DRUG SCREENING; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; SYNTHESIS; SYSTEM ANALYSIS;

ALGORITHMS; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER GRAPHICS; COMPUTER SIMULATION; COST-BENEFIT ANALYSIS; DIPEPTIDES; DRUG DESIGN; INDICATORS AND REAGENTS; MASS SPECTROMETRY; MODELS, CHEMICAL; MONTE CARLO METHOD; PEPTIDE LIBRARY;

EID: 0034351502     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1093-3263(00)00072-3     Document Type: Article

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