Molecular motors in the heart

Essays in Biochemistry

Volumn 35, Issue , 2000, Pages 145-158

  Davison, Fergus D ^a   D'Cruz, Leon G ^a   McKenna, William J ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR MOTOR; MYOSIN; TROPOMYOSIN; TROPONIN; TROPONIN TROPOMYOSIN COMPLEX; TROPONIN-TROPOMYOSIN COMPLEX;

ANIMAL; HEART; HEART MUSCLE; HUMAN; METABOLISM; PHYSIOLOGY; REVIEW;

ANIMALS; HEART; HUMANS; MOLECULAR MOTOR PROTEINS; MYOCARDIUM; MYOSINS; TROPOMYOSIN; TROPONIN;

EID: 0034351425     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/bse0350145     Document Type: Article

References (20)

1. Berne, R.M. & Levy, M.N. (eds.) (1996) Principles of Physiology, 2nd edn., Mosby, St Louis
2. Kitamura, K., Tokunaga, M., Iwane, A.H. & Yanagida, T.R. (1999) A single myosin head moves along an actin filament with regular steps of 5.3 nanometres. Nature (London) 397, 129-134
3. 2+-binding sites in cardiac slow skeletal-muscle troponin-C perform distinct functions - site-I alone cannot trigger contraction. Proc. Natl. Acad. Sci. U.SA. 87, 9538-9542
4. 2+-deficient EF-hand in cardiac-muscle, with genetically engineered cardiac-skeletal chimeric troponin-C. J. Biol. Chem. 267, 25073-25077
5. Van Eerd, J. & Takahashi, K. (1975) The amino acid sequence of bovine cardiac tamponin-C. Comparison with rabbit skeletal troponin-C. Biochem. Biophys. Res. Commun. 64, 122-127
6. Spyracopoulos, L., Li, M.X., Sia, S.K., Gagne, S.M., Chandra, M., Solaro, R.J. & Sykes, B.D. (1997) Calcium-induced structural transition in the regulatory domain of human cardiac troponin C. Biochemistry 36, 12138-12146
7. Liao, R.L., Wang, C.K. & Cheung, H.C. (1994) Coupling of calcium to the interaction of troponin-I with troponin-C from cardiac muscle. Biochemistry 33, 12729-12734
8. Sasse, S., Brand, N.J., Kyprianou, P., Dhoot, G.K., Wade, R., Aria, M., Periasamy, Yacoub, M.H. & Barton, P.J. (1993) Troponin-I gene-expression during human cardiac development and in end-stage heart failure. Circ. Res. 72, 932-938
9. Hunkeler, N.M., Kullman, J. & Murphy, A.M. (1991) Troponin-I isoform expression in human heart. Circ Res. 69, 409-414
10. Bhavsar, P.K., Dhoot, G.K., Cumming, D.V.E., Butler-Browne, G.S., Yacoub, M.H. & Barton, P.J. (1991) Developmental expression of troponin-I isoforms in fetal human heart. FEBS Lett. 292, 5-8
11. Huang, X.P., Pi, Y.Q., Lee, K.J., Henkel, A.S., Gregg, R.G., Powers, P.A. & Walker, J.W. (1999) Cardiac troponin I gene knockout - a mouse model of myocardial troponin I deficiency. Circ. Res 84, 1-8
12. Schwartz, K., Carrier, L., Guicheney, P. & Komajda, M.R. (1995) Molecular-basis of familial cardiomyopathies. Circulation 91, 532-540
13. Schaub, M.C., Hefti, M.A., Harder, B.A. & Eppenberger, H.M.R. (1997) Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes. J. Mol. Med. 75, 901-920
14. Marian, A.J. & Roberts, R.R. (1995) Recent advances in the molecular-genetics of hypertrophic cardiomyopathy. Circulation 92, 1336-1347
15. Spirito, P., Seidman, C.E., McKenna, W.J. & Maron, B.J. (1997) Medical progress - the management of hypertrophic cardiomyopathy. N. Engl. J. Med. 336, 775-785
16. Sweeney, H.L., Feng, H.S.S., Yang, Z.H. & Watkins, H. (1998) Functional analyses of troponin T mutations that cause hypertrophic cardiomyopathy: insights into disease pathogenesis and troponin function. Proc Natl. Acad. Sci. U.S.A. 95, 14406-14410
17. Strauss, J.D., Van Eyk, J.E., Barth, Z., Wiesner, R.J., Ruegg, J.C. & Kluwe, L. (1996) Recombinant troponin I substitution and calcium responsiveness in skinned cardiac muscle. Pflugers Arch. Eur. J. Physiol. 431, 853-862
18. Liao, R., Gwathmey, J.K. & Wang, C.K. (1998) Functional significance of two missense mutations in troponin C found in human myocardium with idiopathic dilated cardiomyopathy. Circulation 98, 3288 (abstract)
19. Franzen, B., Linder, S., Uryu, K., Alaiya, A.A., Hirano, T., Kato, H. & Auer, G.(1996) Expression of tropomyosin isoforms in benign and malignant human breast lesions. Br. J. Cancer 73, 909-913
20. Braverman, R.H., Cooper, H.L., Lee, H.S. & Prasad, G.L. (1996) Anti-oncogenic effects of tropomyosin - isoform specificity and importance of protein-coding sequences. Oncogene 13, 537-545