Combined vitamins B 12b and C induce the glutathione depletion and the death of epidermoid human larynx carcinoma cells HEp-2

Bioscience Reports

Volumn 20, Issue 5, 2000, Pages 411-417

  Akatov, V S ^a   Evtodienko, Y V ^a   Leshchenko, V V ^a   Teplova, V V ^a   Potselueva, M M ^a   Kruglov, A G ^a   Lezhnev, E I ^a   Yakubovskaya, R I ^b  

^a INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

Ascorbic acid; Cytotoxicity; Glutathione; Hydrogen peroxide; Tumor cells; Vitamin B 12b

Indexed keywords

ASCORBIC ACID; CATALASE; CYANOCOBALAMIN; GLUTATHIONE; HYDROGEN PEROXIDE; LUMINOL; SUPEROXIDE DISMUTASE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG CYTOTOXICITY; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LARYNX CARCINOMA; OXIDATIVE STRESS; CELL CULTURE; CELL DIVISION; DRUG EFFECT; DRUG POTENTIATION; LARYNX TUMOR; METABOLISM; OXIDATION REDUCTION REACTION; SQUAMOUS CELL CARCINOMA;

ASCORBIC ACID; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; DRUG SYNERGISM; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; LARYNGEAL NEOPLASMS; OXIDATION-REDUCTION; TUMOR CELLS, CULTURED; VITAMIN B 12;

EID: 0034351382     PISSN: 01448463     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010386102562     Document Type: Article

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