Targeting of HIV-1 Nef to the centrosome: Implications for antigen processing

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Volumn 1, Issue 11, 2000, Pages 884-891

  Lacaille, Vashti G ^a   Androlewicz, Matthew J ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

Antigen processing; Centrosome; HIV Nef; Viral immunity

Indexed keywords

HYBRID PROTEIN; NEF PROTEIN; NOCODAZOLE; PRIMER DNA;

ANIMAL; ANTIGEN PRESENTATION; ARTICLE; CELL STRAIN COS1; CENTROSOME; DRUG EFFECT; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE;

ANIMALS; ANTIGEN PRESENTATION; BASE SEQUENCE; CENTROSOME; COS CELLS; DNA PRIMERS; GENE PRODUCTS, NEF; HIV-1; HUMANS; NOCODAZOLE; RECOMBINANT FUSION PROTEINS;

EID: 0034331992     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2000.011107.x     Document Type: Article

References (15)

1. Yewdell JW, Bennink JR, Smith GL, Moss B. Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes. Proc Natl Acad Sci USA 1985;82: 1785-1789.
2. McMichael AJ, Michie CA, Gotch FM, Smith GL, Moss B. Recognition of influenza A virus nucleoprotein by human cytotoxic T lymphocytes. J Gen Virol 1986;67: 719-726.
3. Ferrari C, Penna A, Bertoletti A, Valli A, Antoni A, Giuberti T, Cavalli A, Petit M-A, Fiaccadori F. Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection. J Immunol 1990;145: 3442-3449.
4. Ferrari C, Bertoletti A, Penna A, Cavalli A, Valu A, Missale G, Pilli M, Fowler P, Giuberti T, Chisari F, Fiaccadori F. Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen. J Clin Invest 1991;88: 214-222.
5. Boppana SB, Britt WJ. Recognition of human cytomegalovirus gene products by HCMV-specific cytotoxic T cells. Virology 1996;222: 293-296.
6. Hopkins JI, Fiander AN, Evans AS, Delchambre M, Gheysen D, Borysiewicz LK. Cytotoxic T cell immunity to human cytomegalovirus glycoprotein B. J Med Virol 1996;49: 124-131.
7. Hammond SA, Bollinger RC, Tobery TW, Siliciano RF. Transporter-independent processing of HIV-1 envelope protein for recognition by CD8+ T cells. Nature 1993;364: 158-161.
8. Hammond SA, Johnson RP, Kalams SA, Walker BD, Takiguchi M, Safrit JT, Koup RA, Siliciano RF. An epitope-selective, transporter associated with antigen presentation (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen-processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL. J Immunol 1995;154: 6140-6156.
9. Pamer E, Cresswell P. Mechanisms of MHC class I-restricted antigen processing. Annu Rev Immunol 1998;16: 323-358.
10. Yewdell JW, Bennink JR. Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses. Annu Rev Immunol 1999;17: 51-88.
11. Anton LC, Schubert U, Bacik I, Princiotta MF, Wearsch PA, Gibbs J, Day PM, Realini C, Rechsteiner MC, Bennink JR, Yewdell JW. Intracellular localization of proteasomal degradation of a viral antigen. J Cell Biol 1999;146: 113-124.
12. Ferris RL, Hall C, Sipsas NV, Safrit JT, Trocha A, Koup RA, Johnson RP, Siliciano RF. Processing of HIV-1 envelope glycoprotein for class I-restricted recognition: dependence on TAP1/2 and mechanisms for cytosolic localization. J Immunol 1999;162: 1324-1332.
13. Selby M, Erickson A, Dong C, Cooper S, Parham P, Houghton M, Walker CM. Hepatitis C virus envelope glycoprotein E1 originates in the endoplasmic reticulum and requires cytoplasmic processing for presentation by class I MHC molecules. J Immunol 1999;162: 669-676.
14. Wojcik C, Schroeter D, Wilk S, Lamprecht J, Paweletz N. Ubiquitin-mediated proteolysis centers in HeLa cells: indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome. Eur J Cell Biol 1996;71: 311-318.
15. Wigley WC, Fabunmi RP, Lee MG, Marino CR, Muallem S, DeMartino GN, Thomas PJ. Dynamic association of proteasomal machinery with the centrosome. J Cell Biol 1999;145: 481-490.