Ligand diffusion, receptor binding, and internalization: Zeroth-order kinetics

AIChE Journal

Volumn 46, Issue 11, 2000, Pages 2330-2338

  Strieder, William ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; DIFFUSION; GROWTH KINETICS; MATHEMATICAL MODELS; SURFACE REACTIONS;

CELL GROWTH FACTOR INTERNALIZATION; CELL WALL CHEMORECEPTOR; CELLULAR SIGNALING; LIGAND BULK CONCENTRATION; LIGAND DIFFUSION; MASS TRANSPORT RESISTANCE; MICHAELIS-MENTEN CONSTANT; RECEPTOR BINDING; RECEPTOR SITE REACTION CURRENT; ZEROTH ORDER KINETICS;

RATE CONSTANTS;

LIGAND;

ARTICLE; BINDING KINETICS; CALCULATION; CHEMICAL ENGINEERING; DIFFUSION; INTERNALIZATION; LIGAND BINDING; MATHEMATICAL ANALYSIS; RECEPTOR BINDING;

EID: 0034326244     PISSN: 00011541     EISSN: None     Source Type: Journal    
DOI: 10.1002/aic.690461123     Document Type: Article

References (19)

1. Application of the theory of diffusion-controlled reactions to enzyme kinetics
2. Physics of chemorception
3. Diffusion-controlled macromolecular interactions
4. The Influence of net protein charge on the rate of formation of enzyme-substrate complexes
5. Receptor up-regulation, internalization and interconverting receptor sites
6. A kinetic study of protein-protein interactions
7. The sharp interface model: Zeroth order reaction with volume change
8. Diffusion controlled ligand binding to multiple competing cell-bound receptors
9. Cell biology of intracellular protein trafficking
10. Chemoreceptor diffusion and reaction: First order kinetics
11. A steady state model for analyzing the cellular binding internalization and degradation of polypeptide ligands
12. Diffusion controlled ligand binding to spheres partially covered by receptors: An effective medium approach