Analysis of the risk factors for allograft vasculopathy in asymptomatic patients after cardiac transplantation

Arquivos Brasileiros de Cardiologia

Volumn 75, Issue 5, 2000, Pages 421-428

  Bacal, Fernando ^a   Veiga, Viviane Cordeiro ^b   Fiorelli, Alfredo Inácio ^b   Bellotti, Giovanni ^b   Bocchi, Edimar Alcides ^b   Stolf, Noedir Antonio Groppo ^b   Ramires, José Antonio Franchini ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE

Author keywords

Allograft vasculopathy; Cardiac transplantation; Risk factors, body mass index

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BODY MASS; BRAZIL; CHILD; CINEANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; FOLLOW UP; GRAFT REJECTION; HEART TRANSPLANTATION; HUMAN; IMMUNOLOGY; MALE; MIDDLE AGED; RISK FACTOR; STATISTICAL MODEL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BODY MASS INDEX; BRAZIL; CHILD; CINEANGIOGRAPHY; CORONARY DISEASE; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; RISK FACTORS;

EID: 0034322171     PISSN: 0066782X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0066-782X2000001100006     Document Type: Article

References (46)

1. Lower RR, Kontos HA, Kosek JC, Sewell DH, Graham WH. Experiences in heart transplantation. Am J Cardiol 1968; 22: 766-71.
2. Thomson JG. Production of severe atheroma in a transplanted heart. Lancet 1969; 2: 1088-92.
3. Hosenpud J, Mauck K, Hogan K. Cardiac allograft vasculopathy: IgM antibody responses to donor-specific vascular endothelium. Transplantation 1997; 63: 1602-06.
4. Fiorelli A, Stolf N, Graziosi P, et al. Incidência de coronariopatia após o transplante cardíaco ortotópico. Rev Bras Cir Cardiovasc 1994; 9: 69-80.
5. Gao SZ, Alderman EL, Schroeder JS, et al. Clinical and laboratory correlates of accelerated coronary artery disease in the cardiac transplant patient. Circulation 1987; 76: 56-61.
6. Grattan MT, Moreno Cabral CE, Starnes VA, Oyer PE, Stinson EB, Shumway NE. Eight year results of cyclosporine treated patients with cardiac transplants. J Thorac Cardiovasc Surg 1990; 99: 500-09.
7. Greenberg ML, Uretsky BE, Reddy PS, et al. Long term hemodynamic follow-up of cardiac transplant patients treated with cyclosporine and prednisone. Circulation 1985; 71: 487-94.
8. Bocchi E, Vilas-Boas F, Pedrosa AA, et al. Doença coronariana após transplante cardíaco ortotópico. Arq Bras Cardiol 1994; 62: 195-200.
9. Pethig K, Besser K, Heublein B, Wahlers T, Harringer W, Haverich A. Coronary vasculopathy after heart transplantation - effect os temporal onset, severity and pro - gression on long-term prognosis. Z Kardiol 1999; 88: 498-506.
10. Lindelow B, Bergh C, Lamm C, Andersson B, Waagstein F. Graft coronary artery disease is strongly related to the aetiology of heart failure and cellular rejection. Eur Heart 1999; 20: 1326-34.
11. Halle AA, Disciascio G, Massin EK, et al. Coronary angioplasty. atherectomy and bypass surgery in cardiac transplant recipients. J Am Coll Cardiol 1995; 26: 120-8.
12. Davies H, Al-Tikriti S. Coronary arterial pathology in the transplanted human heart. Intern J Cardiol 1989; 25: 99-118.
13. Billingham ME, Cary NRB, Hammond ME, et al. A working formulation for the standartization of nomenclature in the diagnosis of heart and lung rejection: heart rejection study group. J Heart Transplant 1990; 9: 587-601.
14. Sones FM, Shirey EK, Prondfit WL, Westcott RN.Cine-coronary arteriography. Circulation 1959; 20: 773.
15. Uretsky BF, Murali S, Reddy S, et al. Development of coronary artery disease in cardiac transplant patients receiving immunosupressive therapy with cyclosporine and prednisone. Circulation 1987; 76: 827-34.
16. Smart FW, Ballantyne CM, Cocanougher B, et al. Insensitivity of noninvasive tests to detect coronary artery vasculopathy after heart transplant. Am J Cardiol 1991; 67: 243-7.
17. Hardesty RL, Griffith BP, Debsky RF, et al. Experience with cyclosporine in cardiac transplantation. Transplant Proc 1983; 15(suppl 1): 2553 8.
18. HosmerDW, I cmeshow S. Applied Logistic Regression. John Wiley & Sons, 1976: 75-118.
19. SAS Institute Inc.., SAS/STAT â User's Guide. Version 6, Fourth Edit ion, volume 1. Cary, NC: SAS Institute Inc., 1989.
20. Radovancevic B, Poindexter S, Birovljev S, etal. Risk factors for development of accelerated coronary artery disease in cardiac transplant recipients. Eur J Cardiothorac Surg 1990; 4: 309-13.
21. Gao SZ, Schroeder JS, Hunt SA, Valantine HA, Hill IR, Stinson EB. Influence of graft rejection on incidence of accelerated graft coronary artery disease: a new approach to analysis. J Heart Lung Transplant 1993; 12: 1029-35.
22. Costanzo-Nordin MR. Cardiac allograft vasculopathy: relationship with acute cellular rejection and histocompatibility. J Heart Lung Transplant 1992; 11: 90-103.
23. Rose EA, Pepino P, Barr ML, Smith CR, Ratner AJHOE, Berger C. Relation of HLA antibodies and graft atherosclerosis in human cardiac allograft recipients. J Heart Lung Transplant 1992; 11: 120-3.
24. Thompson ME, Shapiro AP, Johnsen AM, et al. The contrasting effects of cyclosporin A and azathioprine on arterial blood pressure and renal function following cardiac transplantation. Int J Cardiol 1986; 11: 219-29.
25. Olivari MT, Antolick A, Ring WS. Arterial hypertension in heart transplant recipients treated with three-drug immunosupressive therapy. J Heart Transplant 1989; 8: 34-9.
26. Hosenpud JD. Coronary artery heart transplantation and its relation to cytomegalovirus. Am Heart J 1999; 138 (5 Pt 2): 469-72.
27. Melnick JL, Adam E, Debakey ME. Cytomegalovirus and atherosclerosis. Eur Heart J 1993; 14: 30-8.
28. Camargo LE. A importância da sorologia, antigenemia e reação em cadeia por polimerase no diagnóstico da infecção pelo citomegalovirus após-transplante cardíaco. Tese de Doutorado) - Faculdade de Medicina da Universidade de São Paulo. São Paulo, 1998: 163p.
29. Smiley ML, Mar EC, Huang ES. Cytomegalovirus infection and viral-induced transformation of human endothelial cells. J Med Virol 1988; 25: 213-26.
30. Grattan MT, Moreno-Cabral CE, Starnes VA, Oyer P, Stinson EB, Shumway NE. Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosis. J Am Med Assn 1989; 261: 3561-6.
31. Wu TC, Hruban RH, Ambinder RF, et al. Demonstration of Cytomegalovirus nucleic acids in the coronary arteries of transplanted hearts. Am J Pathol 1992; 140: 739-47.
32. Merigan TC, Renlund DC, Keay S, et al. A controlled trial of ganciclovir to prevent Cytomegalovirus disease after heart transplantation. N Engl J Med 1992; 326: 1182-6.
33. Keogh A, Simons L, Spratt P, et al. Hyperlipidemia after heart transplantation. J Heart Transplant 1988; 7: 171-5.
34. Becker DM, Chamberlain B, Swank R, et al. Relationship between corticosteroid exposure and plasma lipid levels in heart transplant recipients. Am J Med 1988; 85: 632-8.
35. Chang G, Denofrio D, Desai S, et al. Lipoprotein(a) levels and heart transplantation atherosclerosis. Am Heart Journal 1998; 136(suppl 2): 329-34.
36. Maranhão R, Santos RD, Furlaneto C, et al. Lipoproteína (a), apolipoproteínas e perfil lipídico em fase tardia após-transplante cardíaco Arq Bras Cardiol 1994; 63: 465-8.
37. Bellotti G, Bocchi E, Goiato MAC, et al. Alterações do perfil lipídico na evolução tardia após transplante cardíaco. Arq Bras Cardiol 1996; 66: 263-6.
38. Renlund DG, Bristow MR, Crandall BG, et al. Hypercholesterolemia after heart tranplantation: Amelioration by corticosteroid-free maintenance imunossupression. J Heart Transplant 1989; 8: 214-20.
39. Ballantyne CM, Podet EJ, Patsch WP, et al. Effects of cyclosporine therapy on plasma lipoprotein levels. JAMA 1989; 262: 53-6.
40. Kobashigawa JA, Katznelson S, Laks H, et al. Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med 1995; 333: 621-7.
41. II Consenso Brasileiro sobre Dislipidemias. Arq Bras Cardiol 1996; 67: 1-16.
42. Kobashigawa JA, Murphy FL, Stevenson WL, et al. Low-dose lovastatin safely lowers cholesterol after cardiac transplantation. Circulation 1990; 82: 281-3.
43. Galanos AN, PieperCF, Kussin PS, et al. Relationship of body mass index to subsequent mortality among seriously ill hospitalized patients. Crit Care Med 1997; 25: 1962-75.
44. Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as na independent risk factor for cardiovascular disease: a 26 year follow-up of participants in the Framingham Heart Study. Circulation 1983; 67: 968-77.
45. Winters GL, Kendall TJ, Stanley J, et al. Posttransplant obesity and hyperlipidemia: Major predictors of severity of coronary arteriopathy in failed human heart allografts. J Heart Transplant 1990; 9: 364-71.
46. Hauptman P, Davis S, Miller L, Yeung A. The role of nonimmune risk factors in the development and progression of graft atherosclerosis: preliminary insights from a Multicenter Intravascular Ultrasound Study. J Heart Lung Transplant 1995; 14: 238-42.