Mechanisms of action of quinone-containing alkylating agents: DNA alkylation by aziridinylquinones.

Frontiers in bioscience : a journal and virtual library

Volumn 5, Issue , 2000, Pages

  Hargreaves, R H ^a   Hartley, J A ^a   Butler, J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 DIMETHYL 3,6 DIAZIRIDINYL 1,4 BENZOQUINONE; 2,5-DIMETHYL-3,6-DIAZIRIDINYL-1,4-BENZOQUINONE; 5 (1 AZIRIDINYL) 3 HYDROXYMETHYL 2 (3 HYDROXY 1 PROPENYL) 1 METHYL 4,7 INDOLEDIONE; 6 N AZIRIDINYL 3 HYDROX 7 METHYL 2,3 DIHYDRO 1H PYRROLO(1,2 A)BENZIMIDAZOLE 5,8 DIONE 3 ACETATE; 6-N-AZIRIDINYL-3-HYDROX-7-METHYL-2,3-DIHYDRO-1H-PYRROLO(1,2-A)BENZIMIDAZOLE-5,8-DIONE 3-ACETATE; ALKYLATING AGENT; AZIRIDINE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; BENZOQUINONE DERIVATIVE; CARBOQUONE; DIAZIQUONE; DNA; DOXORUBICIN; INDOLE DERIVATIVE; MITOMYCIN; QUINONE DERIVATIVE;

ALKYLATION; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; OXIDATION REDUCTION REACTION; REVIEW; STRUCTURE ACTIVITY RELATION;

ALKYLATION; ANTINEOPLASTIC AGENTS, ALKYLATING; AZIRIDINES; BENZIMIDAZOLES; BENZOQUINONES; CARBAZILQUINONE; DNA; DOXORUBICIN; HUMANS; INDOLEQUINONES; INDOLES; MITOMYCIN; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; QUINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

MLCS; MLOWN;

EID: 0034321640     PISSN: None     EISSN: 10934715     Source Type: Journal    
DOI: 10.2741/hargreav     Document Type: Review

References (50)