Alteration of the endocytotic pathway by photosensitization with fluoroquinolones

Photochemistry and Photobiology

Volumn 72, Issue 4, 2000, Pages 458-463

  Ouedraogo G ^a,b   Morliere P ^a,b   Maziere C ^c   Maziere J C ^c   Santus, R ^a,b  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c AMIENS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1' DIOCTADECYL 3,3,3',3' TETRAMETHYLINDOCARBOCYANINE PERCHLORATE; 3,3' DIOCTADECYLOXACARBOCYANINE PERCHLORATE; BAYY 3118; CARBOCYANINE; CELL SURFACE RECEPTOR; CIPROFLOXACIN; LOMEFLOXACIN; LOW DENSITY LIPOPROTEIN; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; NORFLOXACIN; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DEPOLYMERIZATION; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; INCUBATION TIME; LYSOSOME; PHOTOSENSITIZATION; PROTEIN BINDING; ULTRAVIOLET A RADIATION;

ANTI-INFECTIVE AGENTS; CELLS, CULTURED; ENDOCYTOSIS; FIBROBLASTS; FLUOROQUINOLONES; HUMANS; LIPOPROTEINS, LDL; PHOTOSENSITIVITY DISORDERS; SPECTROMETRY, FLUORESCENCE;

EID: 0034309740     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2000)072<0458:AOTEPB>2.0.CO;2     Document Type: Article

References (20)

1. Tokura, Y. (1998) Quinolone photoallergy: photosensitivity dermatitis induced by systemic administration of photohaptenic drugs. J. Dermatol. Sci. 18, 1-10.
2. Ouédraogo, G., P. Morlière, M. Bazin, R. Santus, B. Kratzer, M. A. Miranda and J. V. Castell (1999) Lysosomes are sites of fluoroquinolone photosensitization in human skin fibroblasts: a microspectrofluorometric approach. Photochem. Photobiol. 70, 123-129.
3. Djavaheri-Mergny, M., J. C. Mazière, R. Santus, L. Mora, C. Mazière, M. Auclair and L. Dubertret (1993) Exposure to long wavelength ultraviolet radiation decreases processing of low density lipoprotein by cultured human fibroblasts. Photochem. Photobiol. 57, 302-305.
4. Djavaheri-Mergny, M., C. Mazière, R. Santus, L. Dubertret and J. C. Mazière (1994) Ultraviolet A decreases epidermal growth factor (EGF) processing in cultured human fibroblasts and keratinocytes: inhibition of EGF-induced diacylglycerol formation J. Investig. Dermatol. 102, 192-196.
5. Martinez, L. J., R. H. Sik and C. F. Chignell (1998) Fluoroquinolone antimicrobials: singlet oxygen, superoxide and phototoxicity. Photochem. Photobiol. 67, 399-403.
6. Kohen, E., R. Santus and J. G. Hirschberg (1995) Photobiology. Academic Press, Orlando.
7. Zamanski, G. B. and I. N. Chou (1991) Ultraviolet radiation induces cytoskeletal damage in human cells. In Photobiology (Edited by E. Riklis), pp. 727-732. Plenum Press, New York.
8. Djavaheri-Mergny, M., M. T. Pieraggi, C. Mazière, R. Santus, A. Lageron, R. Salvayre, L. Dubertret and J. C. Mazière (1994) Early alterations of actin in cultures human keratinocytes and fibroblasts exposed to long wavelength radiations. Possible involvement in the UVA-induced perturbations of endocytotic processes. Photochem. Photobiol. 59, 48-52.
9. Wehland, J. and K. Weber (1981) Actin rearrangement in living cells revealed by microinjection of a fluorescent phalloidin derivative. Eur. J. Cell Biol. 24, 176-183.
10. Parker, C. A. (1968) Photoluminescence of solutions. Elsevier, Amsterdam.
11. Bjornson, L. K., H. J. Hayden, E. Miller and A. N. Moshell (1976) The transport of alpha-tocopherol and beta-carotene in human blood. J. Lipid Res. 17, 343-351.
12. Carillet, V., P. Morlière, J. C. Mazière, G. Huppe, R. Santus and L. Dubertret (1990) In vitro interactions of the aromatic retinoids Ro 10-9359 (etretinate) and Ro 10-1670 (acitretin), its main metabolite, with human serum lipoproteins and albumin. Biochim. Biophys. Acta 1055, 98-101.
13. Mazière, J. C., P. Morlière and R. Santus (1991) The role of the low density lipoprotein receptor pathway in the delivery of lipophilic photosensitizers in the photodynamic therapy of tumors. J. Photochem. Photobiol. B: Biol. 8, 351-360.
14. Dunn, K. W., S. Mayor, J. N. Myers and F. R. Maxfield (1994) Applications of ratio fluorescence spectroscopy in the study of cell physiology. FASEB J. 8, 573-582.
15. Van Deurs, B., P. K. Holm, L. Kayser and K. Sandvig (1995) Delivery to lysosomes in human carcinoma cell line Hep-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes. Eur. J. Cell Biol. 66, 309-323.
16. Berg, K. (1996) Mechanisms of cell damage in photodynamic therapy. In The Fundamental Bases of Phototherapy (Edited by A. Young, H. Honigsmann and G. Jori), pp. 181-207. OEMF, Milan.
17. Morlière, P., E. Kohen, J. P. Reyftmann, R. Santus, C. Kohen, J. C. Mazière, S. Goldstein, W. F. Mangel and L. Dubertret (1987) Photosensitization by porphyrins delivered to L cell fibroblasts by human serum low density lipoproteins. A microspectrofluorometric study. Photochem. Photobiol. 46, 183-191.
18. Berg, K. and J. Moan (1997) Lysosomes and microtubules as targets for photochemotherapy of cancer. Photochem. Photobiol. 65, 403-409.
19. Quiec, D., C. Mazière, M. Auclair, R. Santus, J. Gardette, G. Redziniak, J. Franchi, L. Dubertret and J. C. Mazière (1995) Lovastatin enhances the phototoxicity of UVA radiation towards cultured NCTC 2544 human keratinocytes: prevention by cholesterol supplementation and by a cathepsin inhibitor. Biochem. J. 310, 305-309.
20. Ouédraogo, G., P. Morlière, R. Santus, M. A. Miranda and J. V. Castell (2000) Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones. J. Photochem. Photobiol. B: Biol. (In press)