Human anti-heparin-platelet factor 4 antibodies are capable of activating primate platelets: Towards the development of a HIT model in primates

Thrombosis Research

Volumn 100, Issue 1, 2000, Pages 47-54

  Ahmad, Sarfraz ^a   Jeske, Walter P ^a   Walenga, Jeanine M ^a   Aldabbagh, Amjad ^a   Iqbal, Omer ^a   Fareed, Jawed ^a,b  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Animal model; Antibody; Heparin; Platelets; Primates

Indexed keywords

ADENOSINE DIPHOSPHATE; COLLAGEN; FIBRINOGEN RECEPTOR; HEPARIN; IMMUNOGLOBULIN; PADGEM PROTEIN; PENTASACCHARIDE; THROMBOCYTE FACTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HYPOTHESIS; IMMUNOGLOBULIN BLOOD LEVEL; MACACA; MICROPARTICLE ENZYME IMMUNOASSAY; NONHUMAN; PRIMATE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; SEROTONIN RELEASE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA;

ANIMAL; AUTOANTIBODIES; BLOOD PLATELETS; CARBON RADIOISOTOPES; COMPARATIVE STUDY; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPARIN; HUMAN; IMMUNOGLOBULIN G; MACACA MULATTA; P-SELECTIN; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET FACTOR 4; PRIMATES; SEROTONIN; THROMBOCYTOPENIA;

EID: 0034306781     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(00)00304-2     Document Type: Article

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