Stochastic multidimensional hypercubes and inverse agonism

Trends in Pharmacological Sciences

Volumn 21, Issue 10, 2000, Pages 362-363

  Milligan, Graeme ^a   Ijzerman, Adivann P ^b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; NEUROLEPTIC AGENT; PHENTOLAMINE; RECEPTOR; SEROTONIN AGONIST;

AGONIST; ANIMAL EXPERIMENT; CONFERENCE PAPER; DRUG ANTAGONISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOCHASTIC MODEL; STRUCTURE ACTIVITY RELATION; TRANSGENIC ANIMAL; TRANSGENIC MOUSE;

ANIMAL; GTP-BINDING PROTEINS; HAMSTERS; MICE; MICE, TRANSGENIC; RECEPTORS, ADRENERGIC, BETA-2; SEROTONIN AGONISTS; STOCHASTIC PROCESSES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034306612     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01540-6     Document Type: Conference Paper

References (2)

1. Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery
2. Resolution of inverse agonist-induced upregulation from constitutive activity of mutants of α(1B)-adrenoceptor