메뉴 건너뛰기




Volumn 25, Issue 9-10, 2000, Pages 1241-1244

Pharmacological and Functional Characterization of Astrocytic GABa Transport: A Short Review

Author keywords

Anticonvulsants; Cloned GABA transporters; Epilepsy; Neuron glia; Seizures

Indexed keywords

ANIMALIA;

EID: 0034305536     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1007692012048     Document Type: Article
Times cited : (79)

References (35)
  • 1
    • 0002587841 scopus 로고
    • γ-Aminobutyric acid in brain: Its formation from glutamic acid
    • Roberts, E. and Frankel, S. 1950. γ-Aminobutyric acid in brain: its formation from glutamic acid. J. Biol. Chem. 187:55-63.
    • (1950) J. Biol. Chem. , vol.187 , pp. 55-63
    • Roberts, E.1    Frankel, S.2
  • 2
    • 0014271426 scopus 로고
    • Biochemical-physiological correlations in studies of the γ-aminobutyric acid system
    • Roberts, E. and Kuriyama, K. 1968. Biochemical-physiological correlations in studies of the γ-aminobutyric acid system. Brain Res. 8:1-35.
    • (1968) Brain Res. , vol.8 , pp. 1-35
    • Roberts, E.1    Kuriyama, K.2
  • 3
    • 0016009689 scopus 로고
    • Amino acid transmitters in the mammalian central nervous system
    • Curtis, D. R. and Johnston, G. A. R. 1974. Amino acid transmitters in the mammalian central nervous system. Pages 97-188, in Rev. Physiol. Vol. LXIX.
    • (1974) Rev. Physiol. , vol.69 , pp. 97-188
    • Curtis, D.R.1    Johnston, G.A.R.2
  • 4
    • 0017908779 scopus 로고
    • Action and uptake of neurotransmitters in CNS tissue culture
    • Hösli, L. and Hösli, E. 1978. Action and uptake of neurotransmitters in CNS tissue culture. Rev. Physiol. Biochem. Pharmacol. 81:135-188.
    • (1978) Rev. Physiol. Biochem. Pharmacol. , vol.81 , pp. 135-188
    • Hösli, L.1    Hösli, E.2
  • 5
    • 0015215606 scopus 로고
    • Autoradiography of some suspected neurotransmitter substances: GABA, glycine, glutamic acid, histamine, dopamine, and L-dopa
    • Ehinger, B. and Falck, B. 1971. Autoradiography of some suspected neurotransmitter substances: GABA, glycine, glutamic acid, histamine, dopamine, and L-dopa. Brain Res. 33:157-172.
    • (1971) Brain Res. , vol.33 , pp. 157-172
    • Ehinger, B.1    Falck, B.2
  • 6
    • 0015149289 scopus 로고
    • Glial cell function: Uptake of transmitter substances
    • Henn, F. A. and Hamberger, A. 1971. Glial cell function: Uptake of transmitter substances. Proc. Natl. Acad. Sci. USA 68: 2686-2690.
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 2686-2690
    • Henn, F.A.1    Hamberger, A.2
  • 7
    • 0015511117 scopus 로고
    • Spinal cord tissue cultures - A model for autoradiographic studies on uptake of putative neurotransmitters such as glycine and GABA
    • Hösli, E., Ljungdahl, Å., Hökfelt, T., and Hösli, L. 1972. Spinal cord tissue cultures - A model for autoradiographic studies on uptake of putative neurotransmitters such as glycine and GABA. Experientia 68:1342-1344.
    • (1972) Experientia , vol.68 , pp. 1342-1344
    • Hösli, E.1    Ljungdahl, Å.2    Hökfelt, T.3    Hösli, L.4
  • 8
    • 0016695013 scopus 로고
    • Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells
    • Iversen, L. L. and Kelly, J. S. 1975. Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells. Biochem. Pharmacol. 24:933-938.
    • (1975) Biochem. Pharmacol. , vol.24 , pp. 933-938
    • Iversen, L.L.1    Kelly, J.S.2
  • 10
    • 0015975415 scopus 로고
    • Uptake of neurotransmitters by clonal lines of astrocytoma and neuroblastoma in culture. I. Transport of γ-aminobutyric acid
    • Hutchison, H. T., Werrbach, K., Vance, C., and Haber, B. 1974. Uptake of neurotransmitters by clonal lines of astrocytoma and neuroblastoma in culture. I. Transport of γ-aminobutyric acid. Brain Res. 66:265-274.
    • (1974) Brain Res. , vol.66 , pp. 265-274
    • Hutchison, H.T.1    Werrbach, K.2    Vance, C.3    Haber, B.4
  • 11
    • 0015969442 scopus 로고
    • On the role of glial cells in the mammalian nervous system: Uptake, excretion, and metabolism of putative neurotransmitters by cultured glial tumor cells
    • Schrier, B. K. and Thompson, E. J. 1974. On the role of glial cells in the mammalian nervous system: uptake, excretion, and metabolism of putative neurotransmitters by cultured glial tumor cells. J. Biol. Chem. 249:1769-1780.
    • (1974) J. Biol. Chem. , vol.249 , pp. 1769-1780
    • Schrier, B.K.1    Thompson, E.J.2
  • 12
    • 0016432174 scopus 로고
    • The uptake of GABA by clonal nerve and glia
    • Schubert, D. 1975. The uptake of GABA by clonal nerve and glia. Brain Res. 84:87-98.
    • (1975) Brain Res. , vol.84 , pp. 87-98
    • Schubert, D.1
  • 13
    • 0017591003 scopus 로고
    • Uptake and metabolism of GABA in astrocytes cultured from dissociated mouse brain hemispheres
    • Schousboe, A., Hertz, L., and Svenneby, G. 1977. Uptake and metabolism of GABA in astrocytes cultured from dissociated mouse brain hemispheres. Neurochem. Res. 2:217-229.
    • (1977) Neurochem. Res. , vol.2 , pp. 217-229
    • Schousboe, A.1    Hertz, L.2    Svenneby, G.3
  • 14
    • 0018225625 scopus 로고
    • Evidence for net uptake of GABA into mouse astrocytes in primary cultures - Its sodium dependence and potassium independence
    • Hertz, L., Wu, P. H., and Schousboe, A. 1978. Evidence for net uptake of GABA into mouse astrocytes in primary cultures - Its sodium dependence and potassium independence. Neurochem. Res. 3:313-323.
    • (1978) Neurochem. Res. , vol.3 , pp. 313-323
    • Hertz, L.1    Wu, P.H.2    Schousboe, A.3
  • 15
    • 0002602845 scopus 로고
    • Primary cultures of GABAergic and glutamatergic neurons as model systems to study neurotransmitter functions. I. Differentiated cells
    • Vernadakis, A., Privat, A., Lauder, J. M., Timiras, P. S., and Giacobini, E. (eds.), M. Nijhoff Publ. Comp. Boston
    • Hertz, L. and Schousboe, A. 1987. Primary cultures of GABAergic and glutamatergic neurons as model systems to study neurotransmitter functions. I. Differentiated cells. Pages 19-31, in Vernadakis, A., Privat, A., Lauder, J. M., Timiras, P. S., and Giacobini, E. (eds.), Model Systems of Development and Aging of the Nervous System, M. Nijhoff Publ. Comp. Boston.
    • (1987) Model Systems of Development and Aging of the Nervous System , pp. 19-31
    • Hertz, L.1    Schousboe, A.2
  • 16
    • 0010220867 scopus 로고
    • Neurochemical alterations associated with epilepsy or seizure activity
    • Dam, M., and Gram, L. (eds.), Raven Press, NY
    • Schousboe, A. 1990. Neurochemical alterations associated with epilepsy or seizure activity. Pages 1-16, in Dam, M., and Gram, L. (eds.), Comprehensive Epileptology. Raven Press, NY.
    • (1990) Comprehensive Epileptology , pp. 1-16
    • Schousboe, A.1
  • 18
    • 0003033325 scopus 로고    scopus 로고
    • Sodium-coupled GABA and glutamate transporters: Structure and function
    • Reith, M. E. A. (ed.), Humana Press, New Jersey
    • Kanner, B. I. 1997. Sodium-coupled GABA and glutamate transporters: structure and function. Pages 151-169, in Reith, M. E. A. (ed.), Neurotransmitter transporters - Structure, function, and regulation. Humana Press, New Jersey.
    • (1997) Neurotransmitter Transporters - Structure, Function, and Regulation , pp. 151-169
    • Kanner, B.I.1
  • 19
    • 0016409592 scopus 로고
    • 3H]alanine by glia: Association with the glial uptake system for GABA
    • 3H]alanine by glia: Association with the glial uptake system for GABA. Brain Res. 86:243-257.
    • (1975) Brain Res. , vol.86 , pp. 243-257
    • Schon, F.1    Kelly, J.S.2
  • 20
    • 0022479142 scopus 로고
    • Mutual inhibition kinetic analysis of γ-aminobutyric acid, taurine, taurine and β-alanine high affinity transport into neurons and astrocytes: Evidence for similarity between the taurine and β-alanine carriers in both cell types
    • Larsson, O. M., Griffiths, R., Allen, I. C., and Schousboe, A. 1986. Mutual inhibition kinetic analysis of γ-aminobutyric acid, taurine, taurine and β-alanine high affinity transport into neurons and astrocytes: Evidence for similarity between the taurine and β-alanine carriers in both cell types. J. Neurochem. 47:426-432.
    • (1986) J. Neurochem. , vol.47 , pp. 426-432
    • Larsson, O.M.1    Griffiths, R.2    Allen, I.C.3    Schousboe, A.4
  • 21
    • 0042945468 scopus 로고
    • GABA uptake inhibitors as anticonvulsants
    • Tunnicliff, G., and Raess, B. U. (eds.), Wiley Liss, New York
    • Schousboe, A., Larsson, O. M., and Krogsgaard-Larsen, P. 1991. GABA uptake inhibitors as anticonvulsants. Pages 165-187, in Tunnicliff, G., and Raess, B. U. (eds.), GABA Mechanisms in Epilepsy. Wiley Liss, New York.
    • (1991) GABA Mechanisms in Epilepsy , pp. 165-187
    • Schousboe, A.1    Larsson, O.M.2    Krogsgaard-Larsen, P.3
  • 22
    • 0042444627 scopus 로고    scopus 로고
    • GABA transporters: Functional and pharmacological properties
    • Egebjerg, J., Schousboe, A., and Krogsgaard-Larsen, P. (eds.), Taylor and Francis Publ., London, in press
    • Schousboe, A. and Kanner, B., 2000. GABA transporters: Functional and pharmacological properties. Pages, in Egebjerg, J., Schousboe, A., and Krogsgaard-Larsen, P. (eds.), Glutamate and GABA Receptors and Transporters. Taylor and Francis Publ., London, in press.
    • (2000) Glutamate and GABA Receptors and Transporters
    • Schousboe, A.1    Kanner, B.2
  • 24
    • 0030955132 scopus 로고    scopus 로고
    • 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABa transporter
    • Thomsen, C., Sørensen, P. O., and Egebjerg, J. 1997. 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA transporter', Br. J. Pharmacol. 120:983-985.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 983-985
    • Thomsen, C.1    Sørensen, P.O.2    Egebjerg, J.3
  • 26
    • 0032842197 scopus 로고    scopus 로고
    • The GABA paradox: Multiple roles as metabolite, neurotransmitter, and neurodifferentiative agent
    • Waagepetersen, H. S., Sonnewald, U., and Schousboe, A. 1999. The GABA paradox: Multiple roles as metabolite, neurotransmitter, and neurodifferentiative agent. J. Neurochem. 73: 1335-1342.
    • (1999) J. Neurochem. , vol.73 , pp. 1335-1342
    • Waagepetersen, H.S.1    Sonnewald, U.2    Schousboe, A.3
  • 27
    • 0026709603 scopus 로고
    • The γ-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracllular brain levels of GABA in awake rats
    • Fink-Jensen, A., Suzdak, P. D., Swedberg, M. D. B., Judge, M. E., Hansen, L., and Nielsen, P. G. 1992. The γ-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracllular brain levels of GABA in awake rats. Eur. J. Pharmacol. 220: 197-201.
    • (1992) Eur. J. Pharmacol. , vol.220 , pp. 197-201
    • Fink-Jensen, A.1    Suzdak, P.D.2    Swedberg, M.D.B.3    Judge, M.E.4    Hansen, L.5    Nielsen, P.G.6
  • 28
    • 0030005462 scopus 로고    scopus 로고
    • Comparative effects of the GABA uptake inhibitors, tiagabine and NNC-711, on extracellular GABA levels in the rat ventrolateral thalamus
    • Richards, D. A. and Bowery, N. G. 1996. Comparative effects of the GABA uptake inhibitors, tiagabine and NNC-711, on extracellular GABA levels in the rat ventrolateral thalamus. Neurochem. Res. 21:135-140.
    • (1996) Neurochem. Res. , vol.21 , pp. 135-140
    • Richards, D.A.1    Bowery, N.G.2
  • 29
    • 0342813030 scopus 로고    scopus 로고
    • Differential effects of nipecotic acid and 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol on extracellular γ-aminobutyrate levels in rat thalamus
    • Juhász, G., Kékesi, K. A., Nyitrai, G., Dobolyi, A., Krogsgaard-Larsen, P., and Schousboe, A. 1997. Differential effects of nipecotic acid and 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol on extracellular γ-aminobutyrate levels in rat thalamus. Eur. J. Pharmacol. 331:139-144.
    • (1997) Eur. J. Pharmacol. , vol.331 , pp. 139-144
    • Juhász, G.1    Kékesi, K.A.2    Nyitrai, G.3    Dobolyi, A.4    Krogsgaard-Larsen, P.5    Schousboe, A.6
  • 30
    • 0013225770 scopus 로고    scopus 로고
    • GABA Transporters in cultured rat astrocytes and neurons
    • Norenberg, M. D., Vastag, M., and Zhou, B.-G. 2000. GABA Transporters in cultured rat astrocytes and neurons. J. Neurochem. 74(Suppl.):S80.
    • (2000) J. Neurochem. , vol.74 , Issue.SUPPL.
    • Norenberg, M.D.1    Vastag, M.2    Zhou, B.-G.3
  • 31
    • 0018746644 scopus 로고
    • Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA receptor binding
    • Schousboe, A., Thorbek, P., Hertz, L., and Krogsgaard-Larsen, P. 1979. Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA receptor binding. J. Neurochem. 33:181-189.
    • (1979) J. Neurochem. , vol.33 , pp. 181-189
    • Schousboe, A.1    Thorbek, P.2    Hertz, L.3    Krogsgaard-Larsen, P.4
  • 32
    • 0019781092 scopus 로고
    • Effect of homo-β-proline and other heterocyclic GABA analogues on GABA uptake in neurons and astroglial cells and on GABA receptor binding
    • Larsson, O. M., Thorbek, P., Krogsgaard-Larsen, P., and Schousboe, A. 1981. Effect of homo-β-proline and other heterocyclic GABA analogues on GABA uptake in neurons and astroglial cells and on GABA receptor binding. J. Neurochem. 37:1509-1516.
    • (1981) J. Neurochem. , vol.37 , pp. 1509-1516
    • Larsson, O.M.1    Thorbek, P.2    Krogsgaard-Larsen, P.3    Schousboe, A.4
  • 33
    • 0020663865 scopus 로고
    • Differences in uptake kinetics of cis-3-aminocyclohexane carboxylic acid into neurons and astrocytes in primary cultures
    • Larsson, O. M., Johnston, G. A. R., and Schousboe, A. 1983. Differences in uptake kinetics of cis-3-aminocyclohexane carboxylic acid into neurons and astrocytes in primary cultures. Brain Res. 260:279-285.
    • (1983) Brain Res. , vol.260 , pp. 279-285
    • Larsson, O.M.1    Johnston, G.A.R.2    Schousboe, A.3
  • 34
    • 0023866577 scopus 로고
    • Kinetic characterization of inhibition of γ-aminobutyric acid uptake into cultured neurons and astrocytes by 4,4-diphenyl-3-butenyl derivatives of nipecotic acid and guvacine
    • Larsson, O. M., Falch, E., Krogsgaard-Larsen, P., and Schousboe, A. 1988. Kinetic characterization of inhibition of γ-aminobutyric acid uptake into cultured neurons and astrocytes by 4,4-diphenyl-3-butenyl derivatives of nipecotic acid and guvacine. J. Neurochem. 50:818-823.
    • (1988) J. Neurochem. , vol.50 , pp. 818-823
    • Larsson, O.M.1    Falch, E.2    Krogsgaard-Larsen, P.3    Schousboe, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.