Hypercalcemia induced with the plasma levels of parathyroid hormone-related peptide in multiple myeloma

Internal Medicine

Volumn 39, Issue 10, 2000, Pages 810-813

  Shionoiri, Astushi ^a   Horiuchi, Toshiyuki ^a   Onouchi, Tsuneko ^b   Tsutsumi, Hisashi ^a   Ohta, Masatsugu ^a   Hosoi, Takayuki ^a   Ito, Hideki ^a   Orimo, Hajime ^a  

^a Tokyo Metropolitan Institute of Gerontology   (Japan)

^b TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cytokine; HHM; PTHrP

Indexed keywords

1,25-DIHYDROXYVITAMIN D; AMINO ACID; CALCITRIOL; CALCIUM; CYCLIC AMP; DEOXYPYRIDINOLINE; DRUG DERIVATIVE; INTERLEUKIN 6; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN; PROTEIN; PTHLH PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA; VITAMIN D;

AGED; ARTICLE; BLOOD; BONE MARROW; CASE REPORT; HUMAN; HYPERCALCEMIA; KIDNEY; MALE; METABOLISM; MULTIPLE MYELOMA; OSTEOLYSIS; PATHOLOGY; URINE;

AGED; AMINO ACIDS; BONE MARROW; BONE RESORPTION; CALCIUM; CYCLIC AMP; HUMANS; HYPERCALCEMIA; INTERLEUKIN-6; KIDNEY; MALE; MULTIPLE MYELOMA; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; PROTEINS; TRANSFORMING GROWTH FACTOR BETA; VITAMIN D;

EID: 0034304250     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.39.810     Document Type: Article

References (13)

1. Moseley JM, Kubota M, Diefenbach-Jagger H, et al. Parathyroid hormone-related protein purified from a lung cancer cell line. Proc Natl Acad Sci USA 84: 5048-5052, 1987.
2. Budayr AA, Nissenson RA, Klein RF, et al. Increased serum levels of a parathyroid hormone-like protein in malignancy-associated hypercalcemia. Ann Intern Med 111: 807-812, 1989.
3. Kramer R, Shustic C, Tabak T, Papavasiliou V, Goltzman D. Parathyroid-hormone-related peptide in hematologic malignancies. Am J Med 100: 406-410, 1996.
4. Tamura K, Kubota K, Kurabayashi H, Take H, Shirakura T. Evidence for parathyroid hormone related peptide as a cause of hypercalcemia in myeloma. Blood 84: 1692-1693, 1994.
5. Schneider HG, Kartosogiannis V, Zhou H, Chou ST, Martin TJ, Grill V. Parathyroid hormone related protein mRNA and protein expression in multiple myeloma: a case report. J Bone Miner Res 13: 1640-1643, 1998.
6. Horiuchi T, Miyachi T, Arai T, Nakamura T, Mori M, Ito H. Raised plasma concentrations of parathyroid hormone related peptide in hypercalcemic multiple myeloma. Horm Metab Res 29: 469-471, 1997.
7. Nakamura Y, Bando H, Sintani Y, Yokogoshi Y, Saito S. Serum parathyroid hormone-related protein concentrations in patients with hematologic malignancies or solid tumors. Acta Endocrinol 127: 324-330, 1992.
8. Kawano M, Yamamoto I, Iwato K, et al. Interleukin-1 beta, rather than lymphotoxin, as the major bone resorbing activity in human multiple myeloma. Blood 73: 1646-1649, 1989.
9. Sato K, Fujii Y, Kasono K, et al. Parathyroid hormone-related protein and interleukin-1α synergistically stimulate bone resorption in vitro and increase the serum calcium concentration in mice in vivo. Endocrinology 124: 2172-2178, 1989.
10. Klein B, Zhang XG, Lu ZY, Bataille R. Interleukin-6 in human multiple myeloma. Blood 85: 863-872, 1995.
11. Jilka RL, Hangoc G, Girasole G, et al. Increased osteoclast development after estrogen loss: mediation by interleukin-6. Science 257: 88-91, 1992.
12. Giuse TA. Parathyroid hormone-related protein and bone metastases. Cancer 80: 1572-1580, 1997.
13. Hughes DE, Dai A, Tiffee JC, Li HH, Mundy GR, Boyce BF. Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta. Nat Med 2: 1132-1136, 1996.