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Volumn 54, Issue 5, 2000, Pages 201-209

Calcineurin antagonists inhibit interferon-gamma production by downregulation of interleukin-18 in human mixed lymphocyte reactions

Author keywords

Calcineurin antagonist; Cyclosporin; Tacrolimus

Indexed keywords

CALCINEURIN; CYCLOSPORIN; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 18; TACROLIMUS;

EID: 0034303236     PISSN: 0386300X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (45)
  • 2
    • 0031962617 scopus 로고    scopus 로고
    • Interleukin 18, a cytokine which resembles IL-1 structurally and IL-12 functionally but exerts its effect independently of both
    • Kohno K and Kurimoto M: Interleukin 18, a cytokine which resembles IL-1 structurally and IL-12 functionally but exerts its effect independently of both. Clin Immunol Immunopathol (1998) 86, 11-15.
    • (1998) Clin Immunol Immunopathol , vol.86 , pp. 11-15
    • Kohno, K.1    Kurimoto, M.2
  • 3
    • 0032607876 scopus 로고    scopus 로고
    • IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family
    • Dinarello CA: IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. J Allergy Clin Immunol (1999) 103, 11-24.
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 11-24
    • Dinarello, C.A.1
  • 6
    • 0031568526 scopus 로고    scopus 로고
    • IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12
    • Kohno K, Kataoka J, Ohtsuki T, Suemoto Y, Okamoto I, Usui M, Ikeda M and Kurimoto M: IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol (1997) 158, 1541-1550.
    • (1997) J Immunol , vol.158 , pp. 1541-1550
    • Kohno, K.1    Kataoka, J.2    Ohtsuki, T.3    Suemoto, Y.4    Okamoto, I.5    Usui, M.6    Ikeda, M.7    Kurimoto, M.8
  • 10
    • 0029559927 scopus 로고
    • Molecular mechanisms of immunosuppression by cyclosporin, FK506 and rapamycin
    • Gardenas ME, Zhu D and Heitman J: Molecular mechanisms of immunosuppression by cyclosporin, FK506 and rapamycin. Curr Opin Nephrol Hypertens (1995) 4, 472-477.
    • (1995) Curr Opin Nephrol Hypertens , vol.4 , pp. 472-477
    • Gardenas, M.E.1    Zhu, D.2    Heitman, J.3
  • 11
    • 0030053447 scopus 로고    scopus 로고
    • The actions of cyclosporin A and FK506 on T-lymphocyte activation
    • Mattila PS: The actions of cyclosporin A and FK506 on T-lymphocyte activation. Biochem Soc Trans (1996) 24, 45-49.
    • (1996) Biochem Soc Trans , vol.24 , pp. 45-49
    • Mattila, P.S.1
  • 12
    • 0029122765 scopus 로고
    • Cyclosporine inhibition of calcineurin activity in human leukocytes in vivo is rapidly reversible
    • Batiuk TD, Pazderka F, Enns J, DeCastro L and Halloran PF: Cyclosporine inhibition of calcineurin activity in human leukocytes in vivo is rapidly reversible. J Clin Invest (1995) 96, 1254-1260.
    • (1995) J Clin Invest , vol.96 , pp. 1254-1260
    • Batiuk, T.D.1    Pazderka, F.2    Enns, J.3    DeCastro, L.4    Halloran, P.F.5
  • 13
    • 0030049160 scopus 로고    scopus 로고
    • Cyclosporine inhibition of leukocyte calcineurin is much less in whole blood than in culture medium
    • Batiuk TD, Pazderka F, Enns J, De Castro L and Halloran PF: Cyclosporine inhibition of leukocyte calcineurin is much less in whole blood than in culture medium. Transplantation (1996) 61, 158-161.
    • (1996) Transplantation , vol.61 , pp. 158-161
    • Batiuk, T.D.1    Pazderka, F.2    Enns, J.3    De Castro, L.4    Halloran, P.F.5
  • 15
    • 0030860863 scopus 로고    scopus 로고
    • Interleukin-6 and interferon-gamma gene expression in lung transplant recipients with refractory acute cellular rejection: Implications for monitoring and inhibition by treatment with aerosolized cyclosporine
    • Iacono A, Dauber J, Keenan R, Spichty K, Cai J, Grgurich W, Burckart G, Smaldone G, Pham S, Ohori NP, Yousem S, Williams P, Griffith B and Zeevi A: Interleukin-6 and interferon-gamma gene expression in lung transplant recipients with refractory acute cellular rejection: Implications for monitoring and inhibition by treatment with aerosolized cyclosporine. Transplantation (1997) 64, 263-269.
    • (1997) Transplantation , vol.64 , pp. 263-269
    • Iacono, A.1    Dauber, J.2    Keenan, R.3    Spichty, K.4    Cai, J.5    Grgurich, W.6    Burckart, G.7    Smaldone, G.8    Pham, S.9    Ohori, N.P.10    Yousem, S.11    Williams, P.12    Griffith, B.13    Zeevi, A.14
  • 16
    • 0010449502 scopus 로고
    • The development of large immature mononuclear cells in mixed leukocyte cultures
    • Baib B, Vas MR and Lowenstein L: The development of large immature mononuclear cells in mixed leukocyte cultures. Blood (1964) 23, 271-275.
    • (1964) Blood , vol.23 , pp. 271-275
    • Baib, B.1    Vas, M.R.2    Lowenstein, L.3
  • 17
    • 0014031210 scopus 로고
    • One-way stimulation in mixed leukocyte cultures
    • Bach FH and Voynow NK: One-way stimulation in mixed leukocyte cultures. Science (1966) 153, 545-547.
    • (1966) Science , vol.153 , pp. 545-547
    • Bach, F.H.1    Voynow, N.K.2
  • 18
    • 0018970820 scopus 로고
    • Interferon production by human and murine lymphocytes in response to alloantigens
    • Perussia B, Mangoni L, Engers HD and Trinchieri G: Interferon production by human and murine lymphocytes in response to alloantigens. J Immunol (1980) 125, 1589-1595.
    • (1980) J Immunol , vol.125 , pp. 1589-1595
    • Perussia, B.1    Mangoni, L.2    Engers, H.D.3    Trinchieri, G.4
  • 19
    • 0025374680 scopus 로고
    • Production of interferon in mixed leukocyte cultures from two individuals
    • Cantell K, Koskimies S and Hirvonen S: Production of interferon in mixed leukocyte cultures from two individuals. J Interferon Res (1990) 10, 331-335.
    • (1990) J Interferon Res , vol.10 , pp. 331-335
    • Cantell, K.1    Koskimies, S.2    Hirvonen, S.3
  • 21
    • 0032193770 scopus 로고    scopus 로고
    • IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-gamma production
    • Yoshimoto T, Takeda K, Tanaka T, Ohkusu K, Kashiwamura S, Okamura H, Akira S and Nakanishi K: IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-gamma production. J Immunol (1998) 161, 3400-3407.
    • (1998) J Immunol , vol.161 , pp. 3400-3407
    • Yoshimoto, T.1    Takeda, K.2    Tanaka, T.3    Ohkusu, K.4    Kashiwamura, S.5    Okamura, H.6    Akira, S.7    Nakanishi, K.8
  • 22
    • 0032526840 scopus 로고    scopus 로고
    • Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation
    • Munder M, Mallo M, Eichmann K and Modolell M: Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation. J Exp Med (1998) 187, 2103-2108.
    • (1998) J Exp Med , vol.187 , pp. 2103-2108
    • Munder, M.1    Mallo, M.2    Eichmann, K.3    Modolell, M.4
  • 23
    • 0030777296 scopus 로고    scopus 로고
    • Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2
    • Rothe H, Jenkins NA, Copeland NG and KoIb H: Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. J Clin Invest (1997) 99, 469-474.
    • (1997) J Clin Invest , vol.99 , pp. 469-474
    • Rothe, H.1    Jenkins, N.A.2    Copeland, N.G.3    Koib, H.4
  • 24
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM and Sher A: Functional diversity of helper T lymphocytes. Nature (1996) 383, 787-793.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 25
    • 0030715635 scopus 로고    scopus 로고
    • Cytokine mRNA expression in tolerant heart allografts after immunosuppression with cyclosporine, sirolimus or brequinar
    • Tian L, Stepkowski SM, Qu X, Wang ME, Wang M, Yu J and Kahan BD: Cytokine mRNA expression in tolerant heart allografts after immunosuppression with cyclosporine, sirolimus or brequinar. Transpl Immunol (1997) 5, 189-198.
    • (1997) Transpl Immunol , vol.5 , pp. 189-198
    • Tian, L.1    Stepkowski, S.M.2    Qu, X.3    Wang, M.E.4    Wang, M.5    Yu, J.6    Kahan, B.D.7
  • 26
    • 0028893317 scopus 로고
    • Distinct patterns of Th2 cytokine production during immune activation in pediatric liver allograft recipients
    • Lang T, Krams SM, Villanueva JC, Cox K, So S, Esquivel C and Martinez OM: Distinct patterns of Th2 cytokine production during immune activation in pediatric liver allograft recipients. Transplant Proc (1995) 27, 1146-1147.
    • (1995) Transplant Proc , vol.27 , pp. 1146-1147
    • Lang, T.1    Krams, S.M.2    Villanueva, J.C.3    Cox, K.4    So, S.5    Esquivel, C.6    Martinez, O.M.7
  • 27
    • 0031861951 scopus 로고    scopus 로고
    • IL-13 production by peripheral blood mononuclear cells from patients with atopic dermatitis
    • Takamatsu Y, Hasegawa M, Sato S and Takehara K: IL-13 production by peripheral blood mononuclear cells from patients with atopic dermatitis. Dermatology (1998) 196, 377-381.
    • (1998) Dermatology , vol.196 , pp. 377-381
    • Takamatsu, Y.1    Hasegawa, M.2    Sato, S.3    Takehara, K.4
  • 28
    • 0032103937 scopus 로고    scopus 로고
    • Topical FK506 suppresses cytokine and costimulatory molecule expression in epidermal and local draining lymph node cells during primary skin immune responses
    • Homey B, Assmann T, Vohr HW, Ulrich P, Lauerma Al, Ruzicka T, Lehmann P and Schupper HC: Topical FK506 suppresses cytokine and costimulatory molecule expression in epidermal and local draining lymph node cells during primary skin immune responses. J Immunol (1998) 160, 5331-5340.
    • (1998) J Immunol , vol.160 , pp. 5331-5340
    • Homey, B.1    Assmann, T.2    Vohr, H.W.3    Ulrich, P.4    Lauerma, A.5    Ruzicka, T.6    Lehmann, P.7    Schupper, H.C.8
  • 29
    • 0029995279 scopus 로고    scopus 로고
    • Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31
    • Dolganov G, Bort S, Lovett M, Burr J, Schubert L, Short D, Mogurn M, Gibson C and Lewis DB: Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31. Blood (1996) 87, 3316-3326.
    • (1996) Blood , vol.87 , pp. 3316-3326
    • Dolganov, G.1    Bort, S.2    Lovett, M.3    Burr, J.4    Schubert, L.5    Short, D.6    Mogurn, M.7    Gibson, C.8    Lewis, D.B.9
  • 31
    • 0032519678 scopus 로고    scopus 로고
    • Differential regulation of IL-4 and IL-13 secretion by human basophils: Their relationship to histamine release in mixed leukocyte cultures
    • Redrup AC, Howard BP, MacGlashan DW Jr, Kagey-Sobotka A, Lichtenstein LM and Schroeder JT: Differential regulation of IL-4 and IL-13 secretion by human basophils: Their relationship to histamine release in mixed leukocyte cultures. J Immunol (1998) 160, 1957-1964.
    • (1998) J Immunol , vol.160 , pp. 1957-1964
    • Redrup, A.C.1    Howard, B.P.2    MacGlashan D.W., Jr.3    Kagey-Sobotka, A.4    Lichtenstein, L.M.5    Schroeder, J.T.6
  • 32
    • 0030796322 scopus 로고    scopus 로고
    • FK506 enhances IL-13 production by T cells activated through CD3/CD28
    • Dumont FJ: FK506 enhances IL-13 production by T cells activated through CD3/CD28. Int Arch Allergy Immunol (1997) 114, 300-301.
    • (1997) Int Arch Allergy Immunol , vol.114 , pp. 300-301
    • Dumont, F.J.1
  • 33
    • 0030024033 scopus 로고    scopus 로고
    • Human IL-13 production is negatively influenced by CD3 engagement, enhancement of IL-13 production by cyclosporin A
    • van der Pouw Kraan TC, Boeije LC, Troon JT, Rutschmann SK, Wijdenes J and Aarden LA: Human IL-13 production is negatively influenced by CD3 engagement, enhancement of IL-13 production by cyclosporin A. J Immunol (1996) 156, 1818-1823.
    • (1996) J Immunol , vol.156 , pp. 1818-1823
    • Van Der Pouw Kraan, T.C.1    Boeije, L.C.2    Troon, J.T.3    Rutschmann, S.K.4    Wijdenes, J.5    Aarden, L.A.6
  • 35
    • 0030980222 scopus 로고    scopus 로고
    • Induction of IL-5 expression by IL-2 is resistant to the immunosuppressive agents cyclosporine A and rapamycin
    • Valentine JE and Sewell WA: Induction of IL-5 expression by IL-2 is resistant to the immunosuppressive agents cyclosporine A and rapamycin. Int Immunol (1997) 9, 975-982.
    • (1997) Int Immunol , vol.9 , pp. 975-982
    • Valentine, J.E.1    Sewell, W.A.2
  • 37
    • 0025288654 scopus 로고
    • Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones
    • Gajewski TF, Schell SR and Fitch FW: Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones. J Immunol (1990) 144, 4110-4120.
    • (1990) J Immunol , vol.144 , pp. 4110-4120
    • Gajewski, T.F.1    Schell, S.R.2    Fitch, F.W.3
  • 38
    • 0030011176 scopus 로고    scopus 로고
    • The functional consequences of partial calcineurin inhibition in human peripheral blood mononuclear leucocytes
    • Pazderka F, Enns J, Batiuk TD and Halloran PF: The functional consequences of partial calcineurin inhibition in human peripheral blood mononuclear leucocytes. Transpl Immunol (1996) 4, 23-31.
    • (1996) Transpl Immunol , vol.4 , pp. 23-31
    • Pazderka, F.1    Enns, J.2    Batiuk, T.D.3    Halloran, P.F.4
  • 42
    • 0031568526 scopus 로고    scopus 로고
    • IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12
    • Kohno K, Kataoka J, Ohtsuki T, Suemoto Y, Okamoto I, Usui M, Ikeda M and Kurimoto M: IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol (1997) 158, 1541-1550.
    • (1997) J Immunol , vol.158 , pp. 1541-1550
    • Kohno, K.1    Kataoka, J.2    Ohtsuki, T.3    Suemoto, Y.4    Okamoto, I.5    Usui, M.6    Ikeda, M.7    Kurimoto, M.8
  • 44
    • 0025292175 scopus 로고
    • Inhibition of alloantigen presentation by cyclosporine
    • Little RG IInd, Ebertowski LA and David CS: Inhibition of alloantigen presentation by cyclosporine. Transplantation (1990) 49, 937-944.
    • (1990) Transplantation , vol.49 , pp. 937-944
    • Little R.G. II1    Ebertowski, L.A.2    David, C.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.