Moral solutions in assessing research risk

IRB Ethics and Human Research

Volumn 22, Issue 5, 2000, Pages 7-10

  Miller, Paul B ^a   Weijer, Charles ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOMEDICAL AND BEHAVIORAL RESEARCH; CHILD; HUMAN; HUMAN EXPERIMENT; PROFESSIONAL STANDARD; RISK ASSESSMENT;

BIOMEDICAL AND BEHAVIORAL RESEARCH;

CHILD; ETHICS COMMITTEES, RESEARCH; HUMAN EXPERIMENTATION; HUMANS; NONTHERAPEUTIC HUMAN EXPERIMENTATION; RISK ASSESSMENT; THERAPEUTIC HUMAN EXPERIMENTATION;

EID: 0034286015     PISSN: 01937758     EISSN: None     Source Type: Journal    
DOI: 10.2307/3564222     Document Type: Article

References (16)

1. Kopelman L. Moral problems assessing research risk. IRB 2000; 22(5):3-6.
2. See Kopelman L. Estimating risk in human research. Clinical Research 1981; 29: 1-8, and Kopelman L. When is risk minimal enough for children to be research subjects? In: Kopelman L, Moskop J, eds. Children and Health Care: Moral and Social Issues. Dordrecht: Kluwer Academic Press, 1989:xx-xx.
3. See Kopelman L. Estimating risk in human research. Clinical Research 1981; 29: 1-8, and Kopelman L. When is risk minimal enough for children to be research subjects? In: Kopelman L, Moskop J, eds. Children and Health Care: Moral and Social Issues. Dordrecht: Kluwer Academic Press, 1989:xx-xx.
4. Weijer C. Thinking clearly about research risk: implications of the work of Benjamin Freedman. IRB 1999; 21: 1-5. See also, Freedman B. Equipoise and the ethics of clinical research. New England Journal of Medicine 1987; 317: 141-45; Freedman B, Fuks A, Weijer C. Demarcating research and treatment: a systematic approach for the analysis of the ethics of clinical research. Clinical Research 1992; 40: 653-60; and Freedman B, Fuks A, Weijer C. In loco parentis: minimal risk as an ethical threshold for research upon children. Hastings Center Report 1993; 23(2): 13-19.
5. Weijer C. Thinking clearly about research risk: implications of the work of Benjamin Freedman. IRB 1999; 21: 1-5. See also, Freedman B. Equipoise and the ethics of clinical research. New England Journal of Medicine 1987; 317: 141-45; Freedman B, Fuks A, Weijer C. Demarcating research and treatment: a systematic approach for the analysis of the ethics of clinical research. Clinical Research 1992; 40: 653-60; and Freedman B, Fuks A, Weijer C. In loco parentis: minimal risk as an ethical threshold for research upon children. Hastings Center Report 1993; 23(2): 13-19.
6. Weijer C. Thinking clearly about research risk: implications of the work of Benjamin Freedman. IRB 1999; 21: 1-5. See also, Freedman B. Equipoise and the ethics of clinical research. New England Journal of Medicine 1987; 317: 141-45; Freedman B, Fuks A, Weijer C. Demarcating research and treatment: a systematic approach for the analysis of the ethics of clinical research. Clinical Research 1992; 40: 653-60; and Freedman B, Fuks A, Weijer C. In loco parentis: minimal risk as an ethical threshold for research upon children. Hastings Center Report 1993; 23(2): 13-19.
7. Weijer C. Thinking clearly about research risk: implications of the work of Benjamin Freedman. IRB 1999; 21: 1-5. See also, Freedman B. Equipoise and the ethics of clinical research. New England Journal of Medicine 1987; 317: 141-45; Freedman B, Fuks A, Weijer C. Demarcating research and treatment: a systematic approach for the analysis of the ethics of clinical research. Clinical Research 1992; 40: 653-60; and Freedman B, Fuks A, Weijer C. In loco parentis: minimal risk as an ethical threshold for research upon children. Hastings Center Report 1993; 23(2): 13-19.
8. See ref. 1, Kopelman 2000:xx.
9. McCartney J. Research on children: National Commission says "yes, if." Hastings Center Report 1978; 8(5): 26-31, 28.
10. Levine RJ. Research in emergency situations: the role of deferred consent. JAMA 1995; 273: 1300-3, 1301.
11. See ref. 1, Kopelman 2000:xx.
12. See ref. 1, Kopelman 2000:xx.
13. See ref. 1, Kopelman 2000:xx.
14. See revised list now in effect: Department of Health and Human Services. Categories of research that may be reviewed by the institutional review board (IRB) through an expedited review procedure. Federal Register 1998; November 9: 60664.
15. U.S. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The Belmont Report: Ethical Principles and Guidelines for the Conduct of Research Involving Human Subjects. Washington, D.C.: Department of Health, Education, and Welfare, 1978.
16. Council of International Organizations of Medical Sciences. International Ethical Guidelines for Biomedical Research Involving Human Subjects. Geneva: CIOMS, 1993; Guideline 8.