Functional synaptic connections among respiratory neurons

Respiration Physiology

Volumn 122, Issue 2-3, 2000, Pages 237-246

  Duffin, James ^a   Tian, Guo Feng ^a   Peever, John H ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Control of breathing, respiratory network; Mammals, cat; Network, neuronal, respiration

Indexed keywords

CAT; CONFERENCE PAPER; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RESPIRATION CONTROL; RESPIRATORY NERVE CELL; SYNAPSE;

ANIMALS; HUMANS; MOTOR NEURONS; NEURONS; RESPIRATORY SYSTEM; SYNAPSES;

EID: 0034285058     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(00)00162-6     Document Type: Conference Paper

References (42)

1. Balis U.J., Morris K.F., Koleski J., Lindsey B.G. Simulations of a ventrolateral medullary neural network for respiratory rhythmogenesis inferred from spike train cross- correlation. Biol. Cyber. 70:1994;311-327.
2. Ballanyi K., Onimaru H., Homma I. Respiratory network function in the isolated brainstem-spinal cord of newborn rats. Prog. Neurobiol. 59:1999;583-634.
3. Bianchi A.L., Denavit-Saubié M., Champagnat J. Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol. Rev. 75:1995;1-45.
4. Butera R.J., Rinzel J., Smith J.C. Models of respiratory rhythm generation in the pre-Botzinger complex. II. Populations of coupled pacemaker neurons. J. Neurophysiol. 82:1999;398-415.
5. Duffin J. A model of respiratory rhythm generation. NeuroReport. 2:1991;623-626.
6. Duffin J., Douse M.A. Bötzinger expiratory neurones inhibit propriobulbar decrementing inspiratory neurones. NeuroReport. 4:1993;1215-1218.
7. Duffin J., van Alphen J. Bilateral connections from ventral group inspiratory neurons to phrenic motoneurons in the rat determined by cross-correlation. Brain Res. 694:1995a;55-60.
8. Duffin J., van Alphen J. Cross-correlation of augmenting expiratory neurons of the Bötzinger complex in the cat. Exp. Brain Res. 103:1995b;251-255.
9. Duffin J., Ezure K., Lipski J. Breathing rhythm generation: focus on the rostral ventrolateral medulla. News Physiol. Sci. 10:1995;133-140.
10. Ezure K. Synaptic connections between medullary respiratory neurons and considerations on the genesis of respiratory rhythm. Prog. Neurobiol. 35:1990;429-450.
11. Feldman J.L., McCrimmon D.R. Neural control of breathing. Zigmond M.J., Bloom F.E., Landis S.C., Roberts J.L., Squire L.R. Fundamental Neuroscience. 1999;1063-1090 Academic Press, New York, NY.
12. Gottschalk A., Oglvie M.D., Richter D.W., Pack A.I. Computational aspects of the respiratory pattern generator. Neural Comput. 6:1994;56-68.
13. Hayashi F., Lipski J. The role of inhibitory amino acids in control of respiratory motor output in an arterially perfused rat. Respir. Physiol. 89:1992;47-63.
14. Hilaire G., Duron B. Maturation of the mammalian respiratory system. Physiol. Rev. 79:1999;325-360.
15. Hsieh J.H., Chang Y.C., Su C.K., Hwang J.C., Yen C.T., Chai C.Y. A single minute lesion around the ventral respiratory group in medulla produces fatal apnea in cats. J. Auton. Nerv. Syst. 73:1998;7-18.
16. Kashiwagi M., Onimaru H., Homma I. Correlation analysis of respiratory neuron activity in ventrolateral medulla of brainstem-spinal cord preparation isolated from newborn rat. Exp. Brain Res. 95:1993;277-290.
17. Kirkwood P.A. On the use and interpretation of cross-correlation measurements in the mammalian central nervous system. J. Neurosci. Meth. 1:1979;107-132.
18. Kirkwood P.A., Sears T.A. Interaction between the monosynaptic EPSP and the central respiratory drive potential of expiratory motoneurones in the cat. J. Physiol. Lond. 232:1973;38-40.
19. Koshiya N., Smith J.C. Neuronal pacemaker for breathing visualized in vitro. Nature. 400:1999;360-363.
20. Lindsey B.G., Segers L.S., Shannon R. Discharge patterns of rostrolateral medullary expiratory neurons in the cat: regulation by concurrent network processes. J. Neurophysiol. 61:1989a;1185-1196.
21. Lindsey B.G., Shannon R., Gerstein G.L. Gravitational representation of simultaneously recorded brainstem respiratory neuron spike trains. Brain Res. 483:1989b;373-378.
22. Matsugu M., Duffin J., Poon C.S. Entrainment, instability, quasi-periodicity, and chaos in a compound neural oscillator. J. Comput. Neurosci. 5:1998;35-51.
23. McLean H.A., Remmers J.E. Respiratory motor output of the sectioned medulla of the neonatal rat. Respir. Physiol. 96:1994;49-60.
24. Ogilvie M.D., Gottschalk A., Anders K., Richter D.W., Pack A.I. A network model of respiratory rhythmogenesis. Am. J. Physiol. 263:1992;R962-R975.
25. Onimaru H., Kashiwagi M., Arata A., Homma I. Possible mutual excitatory couplings between inspiratory neurons in caudal ventrolateral medulla of brainstem-spinal cord preparation isolated from newborn rat. Neurosci. Lett. 150:1993;203-206.
26. Onimaru H., Arata A., Homma I. Neuronal mechanisms of respiratory rhythm generation: an approach using in vitro preparation. Jpn. J. Physiol. 47:1997;385-403.
27. Paton J.F.R., Ramirez J.M., Richter D.W. Mechanisms of respiratory rhythm generation change profoundly during early life in mice and rats. Neurosci. Lett. 170:1994;167-170.
28. Peever J.H., Tian G.F., Duffin J. Bilaterally independent respiratory rhythms in the decerebrate rat. Neurosci. Lett. 247:1998;41-44.
29. Ramirez J.M., Quellmalz U.J., Richter D.W. Postnatal changes in the mammalian respiratory network as revealed by the transverse brainstem slice of mice. J. Physiol. Lond. 491:1996;799-812.
30. Ramirez J.M., Telgkamp P., Elsen F.P., Quellmalz U.J., Richter D.W. Respiratory rhythm generation in mammals: synaptic and membrane properties. Respir. Physiol. 110:1997;71-85.
31. Ramirez J.M., Schwarzacher S.W., Pierrefiche O., Olivera B.M., Richter D.W. Selective lesioning of the cat pre-Botzinger complex in vivo eliminates breathing but not gasping. J. Physiol. Lond. 507:1998;895-907.
32. Rekling J.C., Feldman J.L. PreBotzinger complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation. Ann. Rev. Physiol. 60:1998;385-405.
33. Richter D.W., Ballanyi K., Schwarzacher S., Schwarzacher S.W. Mechanisms of respiratory rhythm generation. Curr. Opin. Neurobiol. 2:1992;788-793.
34. Ryback I.A., Paton J.F.R., Schwaber J.S. Modeling neural mechanisms for genesis of respiratory rhythm and pattern. II. Network models of the central respiratory pattern generator. J. Neurophysiol. 77:1997;2007-2026.
35. Smith J.C. New computational models of the respiratory oscillator in mammals. Adv. Exp. Med. Biol. 393:1995;7-13.
36. Smith J.C., Ellenberger H.H., Ballanyi K., Richter D.W., Feldman J.L. Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science. 254:1991;726-729.
37. St. John W.M. Neurogenesis of patterns of automatic ventilatory activity. Prog. Neurobiol. 56:1998;97-117.
38. Tian G.F., Duffin J. Spinal connections of ventral-group bulbospinal inspiratory neurons studied with cross-correlation in the decerebrate rat. Exp. Brain Res. 111:1996;178-186.
39. Tian G.F., Duffin J. Synchronization of ventral-group, bulbospinal inspiratory neurons in the decerebrate rat. Exp. Brain Res. 117:1997;479-487.
40. Tian G.F., Peever J.H., Duffin J. Botzinger-complex expiratory neurons monosynaptically inhibit phrenic motoneurons in the decerebrate rat. Exp. Brain Res. 122:1998;149-156.
41. Tian G.-F., Peever J.H., Duffin J. Bötzinger-complex, bulbospinal expiratory neurons monosynaptically inhibit ventral-group respiratory neurons in the decerebrate rat. Exp. Brain Res. 124:1999a;173-180.
42. Tian G.-F., Peever J.H., Duffin J. Mutual inhibition between Botzinger-complex bulbospinal expiratory neurons detected with cross-correlation in the decerebrate rat. Exp. Brain Res. 125:1999b;440-446.