Efficient preparation of optically active ketoprofen by Mucor javanicus lipase immobilized on an inorganic support

Journal of Bioscience and Bioengineering

Volumn 90, Issue 3, 2000, Pages 332-334

  Kato, Katsuya ^a   Gong, Yuefa ^a   Saito, Takao ^a   Kimoto, Hiroshi ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Enantioselective; Ketoprofen; Lipase; Mucor javanicus; Resolution

Indexed keywords

ACETONE; BIOSYNTHESIS; ENZYME IMMOBILIZATION; ESTERS; HYDROLYSIS; PH EFFECTS;

ENANTIOSELECTIVITY; HYDROLYTIC ENZYMES; KETOPROFEN;

ENZYME KINETICS;

ACETONE; KETOPROFEN; PHOSPHATE; TRIACYLGLYCEROL LIPASE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME IMMOBILIZATION; ENZYME SYNTHESIS; HYDROLYSIS; MUCOR; NONHUMAN; OPTICS; RECYCLING;

MUCOR; MUCOR JAVANICUS;

EID: 0034281828     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(00)80090-0     Document Type: Article

References (10)

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2. Lipases: Interfacial enzymes with attractive applications
3. A facile enzymatic resolution process for the preparation of (+)-S-2-(6-methoxy-2-naphthyl)propionic acid (naproxen)
4. Production of optically active ketoprofen by direct enzymatic esterification
5. Enantioselective esterification 2-arylpropionic acids catalyzed by immobilized Rhizomucor miehei lipase
6. Preparation of optically active trifluoromethylated (3'-indolyl)thiacarboxylic acids, novel plant growth regulators, through lipase-catalyzed enantioselective hydrolysis
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9. Immobilization of lipase on a new inorganic supports, toyonite, and the reactivity and enantioselectivity of the immobilized lipase
10. Optically active 6-acetyloxy-2H-pyran-3(6H)-one obtained by lipase catalyzed transesterification and esterification