Nocturnal O2 enrichment of room air at high altitude increases daytime O2 saturation without changing control of ventilation

High Altitude Medicine and Biology

Volumn 1, Issue 3, 2000, Pages 197-206

  McElroy, Michele K ^a,b   Gerard, Andre ^a,b   Powell, Frank L ^a,b   Prisk, G Kim ^a   Sentse, Nicole ^a,b   Holverda, Sebastiaan ^a,b   West, John B ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute mountain sickness; Hypoxic ventilatory response; Ventilatory response to carbon dioxide

Indexed keywords

ADULT; ALTITUDE; ALTITUDE DISEASE; ARTICLE; CIRCADIAN RHYTHM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; HYPOXEMIA; LUNG VENTILATION; MALE; MIDDLE AGED; OXYGEN THERAPY; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SLEEP APNEA SYNDROME;

ADULT; ALTITUDE; ALTITUDE SICKNESS; ANOXEMIA; CIRCADIAN RHYTHM; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; OXYGEN INHALATION THERAPY; PULMONARY VENTILATION; SLEEP APNEA SYNDROMES;

EID: 0034281194     PISSN: 15270297     EISSN: None     Source Type: Journal    
DOI: 10.1089/15270290050144190     Document Type: Article

References (17)

1. 2 with long-term CPAP therapy for obstructive sleep apnea. Am. Rev. Respir. Dis. 135:144-147.
2. Eichenberger U., Weiss E., Riemann D., Oelz O., and Bartsch P. (1996). Nocturnal periodic breathing and the development of acute high altitude illness. Am. J. Resp. Crit. Care Med. 154:1748-1754.
3. Fuse K., Satoh M., Yokota T., Ohdaira T., Muramatsu Y., Suzuki E., and Arakawa M. (1999). Regulation of ventilation before and after sleep in patients with obstructive sleep apnoea. Respirology 42:125-130.
4. Hackett P.H., and Oelz O. (1992). The Lake Louise consensus on the definition and quantification of altitude illness. In: Hypoxia and Mountain Medicine. J.R. Sutton, G. Coates, and C.S. Houston, eds. Queen City Printers, Burlington; pp. 327-330.
5. Khoo M.C., Anholm J.D., Ko S.W., Downey R. III, Powles A.C., Sutton J.R., and Houston C.S. (1996). Dynamics of periodic breathing and arousal during sleep at extreme altitude. Respir. Physiol. 103:33-43.
6. Leech J.A., Onal E., and Lopata M. (1992). Nasal CPAP continues to improve sleep-disordered breathing and daytime oxygenation over long-term follow-up of occlusive sleep apnea syndrome. Chest 102:1651-1655.
7. Luks A.M., van Melick H., Batarse R.R., Grant I., and West J.B. (1998). Room oxygen enrichment improves sleep and subsequent day-time performance at high altitude. Respir. Physiol. 113:247-258.
8. Megirian D., Ryan A.T., and Sherrey J.H. (1980). An electrophysiological analysis of sleep and respiration of rats breathing different gas mixtures: diaphragmatic muscle function. Electroencephal. Clin. Neurophysiol. 50:303-313.
9. Pappenheimer J.R. (1977). Sleep and respiration of rats during hypoxia. J. Physiol. (London) 266:191-207.
10. Prisk G.K., Elliott A.R., and West J.B. (2000). Sustained microgravity reduces the human ventilatory response to hypoxia but not to hypercapnia. J. Appl. Physiol. 88:1421-1430.
11. Read D.J.C. (1967). A clinical method for assessing the ventilatory response to carbon dioxide. Austral. Ann. Med. 16:20-32.
12. Rebuck A.S., and Campbell E.J. (1974). A clinical method for assessing the ventilatory response to hypoxia. Am. Rev. Respir. Dis. 109:345-350.
13. Reite M., Jackson D., Cahoon R.L., and Weil J.V. (1975). Sleep physiology at high altitude. Electroencephalogr. Clin. Neurophysiol. 38:463-471.
14. Sato, M., Severinghaus J.W., Powell F.L., Xu F.-D., and Spellman M.J., Jr. (1992). Augmented hypoxic ventilatory response in men at altitude. J. Appl. Physiol. 73:101-107.
15. West J.B. (1995). Oxygen enrichment of room air to relieve the hypoxia of high altitude. Respir. Physiol. 99:225-232.
16. White D.P., Douglas N.J., Pickett C.K., Zwillich C.W., and Weil J.V. (1983). Sleep deprivation and the control of ventilation. Am. Rev. Respir. Dis. 128:984-986.
17. Yeh M.P., Gardner R.M., Adams T.D., and Yanowitz F.G. (1982). Computerized determination of pneumotachometer characteristics using a calibrated syringe. J. Appl. Physiol. 53:280-285.