Epitope analysis and primary structures of variable regions of anti-human FcεRI monoclonal antibodies, and expression of the chimeric antibodies fused with human constant regions

Bioscience, Biotechnology and Biochemistry

Volumn 64, Issue 9, 2000, Pages 1856-1867

  Takai, Toshiro ^a,b   Yuuki, Toshifumi ^b   Iwamoto Yasue, Namiko ^b   Okumura, Ko ^a   Ra, Chisei ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ASAHI BREWERIES LTD   (Japan)

Author keywords

Chimeric antibody; Epitope; High affinity IgE receptor; Monoclonal antibody; Variable region

Indexed keywords

EPITOPE; HYBRID PROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL STRAIN COS1; CHEMISTRY; CHO CELL; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE DELETION; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; IMMUNOGLOBULIN CONSTANT REGION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; MUTAGENESIS; NUCLEOTIDE SEQUENCE; RABBIT; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; CHO CELLS; CLONING, MOLECULAR; COS CELLS; CRICETINAE; EPITOPES; ESCHERICHIA COLI; FLOW CYTOMETRY; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN SUBUNITS; RABBITS; RECEPTORS, IGE; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSFECTION;

EID: 0034280609     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.64.1856     Document Type: Article

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