Chelation in Metal Intoxication XLIV : Efficacy of α-Mercapto-β-(5-Substituted, 2-Furyl) Acrylic Acids in Mobilizing Intracellularly Bound Cadmium in Rat

Biomedical and Environmental Sciences

Volumn 13, Issue 3, 2000, Pages 205-212

  Tandon, Sushil K ^a   Prasad, Satgur ^a   Singh, Surendra ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC ACID DERIVATIVE; CADMIUM; CHELATING AGENT; FURAN DERIVATIVE; THIOL DERIVATIVE;

ANIMAL; ARTICLE; CADMIUM POISONING; CHEMISTRY; FECES; FEMALE; METABOLISM; RAT; URINE;

ACRYLATES; ANIMALS; CADMIUM; CADMIUM POISONING; CHELATING AGENTS; FECES; FEMALE; FURANS; RATS; SULFHYDRYL COMPOUNDS;

EID: 0034279935     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Andersen, O. (1999). Principles and recent developments in chelation treatment of metal intoxication. Chem. Rev. 99, 2683-2710.
2. Aposhian, H. V., Levine, D. J., Revera, M., and Fernando, Q. (1993). Determination and metabolism of dithiol chelating agents: The zinc chelate of dimethyl ester of meso-2,3-dimercaptosuccinic acid increases biliary excretion of cadmium and platinum. Chem. Res. Toxicol. 6, 208-214.
3. Aposhian, H. V., Maiorino, R. M., Gonzalez- Ramirez, D., Zuniga- Charles, M. et al. (1995). Mobilization of heavy metals by newer, therapeutically useful chelating agents. Toxicology 97, 23-38.
4. Campaigne, E. and Cline, R. E. (1956). Preparation and absorption spectra of some β-aryl-α-mercapto acrylic acids and related disulfides. J. Org. Chem. 21, 32-38.
5. Goyer, R. A., Cherian, M. G., Jones, M. M., and Reigart, J. R. (1995). Role of chelating agents for prevention, intervention and treatment of exposures to toxic metals. Environ. Health. Perspect. 103, 1048-1052.
6. Jones, M. M. and Cherian, M. G. (1990). The search for chelate antagonist for chronic cadmium intoxication. Toxicology 62, 1-25.
7. Khandelwal, S. and Tandon, S. K. (1991). Time related influence of a-mercapto-β-(2-furyl) acrylic acid (MFA) in cadmium toxicity. Biomed. Environ. Sci. 4, 304-309.
8. Massey, A. G. (1973). Copper. In Comprehensive Inorganic Chemistry, 1st ed. (J. C. Bailor, Jr., H. J. Emeleus, R. Nyholm, A. F. Trotman-Dickenson Eds.), Vol 3, pp. 1-78. Pergamon Press, Oxford.
9. Piscator, M. (1986) The nephropathy of chronic cadmium poisoning. In Handbook of Experimental Pharmacology (E. C. Foulkes, Ed.), Vol. 80, pp. 180-194. Springer-Verlag, New York.
10. Tandon, S. K., Sharma, B. L., and Kachru, D. N. (1989). Chelation in metal intoxication XXX : α-mercapto-β-aryl acrylic acids as antidotes to cadmium toxicity. Pharmacol. Toxicol. 64, 380-382.
11. 3 DTPA and DMPS in the rat. Environ. Toxicol. Pharmacol. 3, 159-165.
12. Webb, M. (1986) Role of metallothionein in cadmium metabolism in Handbook of Experimental Pharmacology (E. C. Foulkes Ed) Vol. 80, pp. 281-325. Springer Verlag, New York.
13. Zar, J. H. (1984). Biostastical Analysis, 2nd ed., pp. 222-226. Englewood cliffs, Prentice Hall, New Jersey.