Secretion, γ-carboxylation, and endoplasmic reticulum-associated degradation of chimeras with mutually exchanged gla domain between human protein C and prothrombin

Thrombosis Research

Volumn 99, Issue 5, 2000, Pages 511-521

  Tokunaga, F ^a   Takeuchi, S ^a   Omura, S ^b   Arvan, P ^c   Koide, T ^a  

^a UNIVERSITY OF HYOGO   (Japan)

^b KITASATO INSTITUTE   (Japan)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Endoplasmic reticulum associated degradation; Proteasome; Protein C; Prothrombin; Quality control

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CYSTEINE PROTEINASE; HYBRID PROTEIN; MULTIENZYME COMPLEX; PROTEASOME; PROTEIN C; PROTHROMBIN; VITAMIN K GROUP; WARFARIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; SECRETION; SEQUENCE ALIGNMENT;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; CRICETINAE; CYSTEINE ENDOPEPTIDASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPLASMIC RETICULUM; HUMANS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN C; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTHROMBIN; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; TRANSFECTION; TUMOR CELLS, CULTURED; VITAMIN K; WARFARIN;

EID: 0034266659     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(00)00258-9     Document Type: Article

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