Low-molecular-weight heparins versus unfractionated heparin in the treatment of deep vein thrombosis and pulmonary embolism

American Journal of Physical Medicine and Rehabilitation

Volumn 79, Issue 5 SUPPL., 2000, Pages

  Merli, Geno J ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

Activated Partial Thromboplastin Time; Deep Vein Thrombosis; Low Molecular Weight Heparin; Physiatrist; Pulmonary Embolism; Rehabilitation; Unfractionated Heparin; Warfarin

Indexed keywords

BLOOD; BLOOD VESSELS; MEDICINE; ORGANIC ACIDS; PATIENT REHABILITATION; POLYSACCHARIDES; PULMONARY DISEASES;

ACTIVATED PARTIAL THROMBOPLASTIN TIME; BLOOD COAGULATION; DEEP VEIN THROMBOSIS; LOW MOLECULAR WEIGHT HEPARIN; PHYSIATRIST; PHYSICAL MEDICINE; PULMONARY EMBOLISM; UNFRACTIONATED HEPARIN; WARFARIN;

PATIENT TREATMENT;

ANTICOAGULANT AGENT; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN;

AMBULATORY CARE; BLEEDING; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DAILY LIFE ACTIVITY; HUMAN; LUNG EMBOLISM; METHODOLOGY; PHYSICAL MEDICINE; REHABILITATION; REVIEW; THROMBOCYTOPENIA; TREATMENT OUTCOME; VEIN THROMBOSIS;

ACTIVITIES OF DAILY LIVING; AMBULATORY CARE; ANTICOAGULANTS; HEMORRHAGE; HEPARIN; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; PHYSICAL MEDICINE; PULMONARY EMBOLISM; REHABILITATION; THROMBOCYTOPENIA; TREATMENT OUTCOME; VENOUS THROMBOSIS;

EID: 0034264161     PISSN: 08949115     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Anderson F, Wheeler H, Goldberg R, et al: A population based perspective of the hospital incidence and case fatality rates of deep vein thrombosis and pulmonary embolism: the Worcester DVT Study. Arch Intern Med 1991;151:933
2. U.S. Department of Health and Human Services. Vital and Health Statistics 1997; 41-3
3. Hirsh J, Levine M: Low molecular weight heparin. Blood 1992;79:1-17
4. Weitz J: Low molecular weight heparins. N Engl J Med 1997;337:688-98
5. Young E, Prins M, Levine M, et al: Heparin binding to plasma proteins, an important mechanism for heparin resistance. Thromb Haemost 1992;67:639-43
6. Simonneau G, Charbonnier B, Decousus H, et al: Subcutaneous low molecular weight heparin compared with continuous intravenous unfractionated heparin in the treatment of proximal deep vein thrombosis. Arch Mem Med 1993;153:1541-6
7. de Valk H, Banga J, Wester J, et al: Comparing subcutaneous danaparoid with intravenous unfractionated heparin for the treatment of venous thromboembolism: a randomized controlled trial. Ann Intern Med 1995;123:1
8. Lindmarker P, Holmstrom M, Granqvist S, et al: Comparison of once daily subcutaneous Fragmin with continuous intravenous unfractionated heparin in the treatment of deep vein thrombosis. Thromb Haemost 1994;72:186-90
9. Hull R, Raskob G, Pineo G, et al: Subcutaneous low molecular weight heparin compared with continuous intravenous heparin in the treatment of proximal vein thrombosis. N Engl J Med 1992;326:975-82
10. The Columbus Investigators: Low molecular weight heparin in the treatment of patients with venous thromboembolism. N Engl J Med 1997;337:657-62
11. Simonneau G, Sors H, Charbonnier B, et al: A comparison of low molecular weight heparin with unfractionated heparin for acute pulmonary embolism. N Engl J Med 1997;337:663-9
12. Partsch H, Kechavarz B, Mostbeck A, et al: Frequency of pulmonary embolism in patients who have iliofemoral deep vein thrombosis and are treated with once or twice daily low molecular weight heparin. J Vasc Surg 1996;24:774-82
13. Spiro T: Enoxaparin versus heparin in the treatment of DVT/PE: the RPR 529 study. Thromb Haemost 1997;78(suppl): 373
14. Levine M, Gent M, Hirsh J, et al: A comparison of low molecular weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep vein thrombosis. N Engl J Med 1996;334:667-81
15. Koopman M, Prandoni P, Piovella F, et al: Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low molecular weight heparin administered at home. N Engl J Med 1996;334:682-7
16. Lensing A, Prins M, Davidson B, et al: Treatment of deep venous thrombosis with low molecular weight heparins: a meta-analysis. Arch Intern Med 1995; 155:601-7
17. Siragusa S, Cosmi B, Piovella F, et al: Low molecular weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: results of a meta-analysis. Am J Med 1996;100: 269-77
18. Leizorovicz A, Simonneau G, Decousus H, et al: Comparison of efficacy and safety of low molecular weight heparins and unfractionated heparin in initial treatment of deep venous thrombosis: a meta-analysis. BMJ 1994;309:299-304
19. Gould M, Dembitzer A, Doyle R, et al: Low molecular weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis: a meta-analysis of radomized, controlled trials. Ann Intern Med 1999;130:800-9
20. Dolovich L, Ginsberg J, Douketis J, et al: A meta-analysis comparing low molecular weight heparins with unfractionated heparin in the treatment of venous thromboembolism: examining some unanswered questions regarding location of treatment, product type, and dosing frequency. Arch Intern Med 2000;160:181-8