New PDE5 inhibitors: More selective than Viagra?

Drug Discovery Today

Volumn 5, Issue 8, 2000, Pages 320-321

  Kingman, Sharon ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

1 [3 [1 [(4 FLUOROPHENYL)METHYL] 7,8 DIHYDRO 8 OXO 1H IMIDAZO[4,5 G]QUINAZOLIN 6 YL] 4 PROPOXYPHENYL]CARBOXAMIDE; CYCLIC GMP; ISOENZYME; PHOSOHODIESTERASE 5 INHIBITOR; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE V; SILDENAFIL; UNCLASSIFIED DRUG; ZAPRINAST;

ANIMAL TISSUE; CONTROLLED STUDY; CORPUS CAVERNOSUM; ENZYME INHIBITION; ERECTILE DYSFUNCTION; FLUSHING; HEADACHE; HUMAN; IN VITRO STUDY; NAUSEA; NONHUMAN; RABBIT; SHORT SURVEY; STRUCTURE ACTIVITY RELATION; VISUAL IMPAIRMENT;

EID: 0034255935     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(00)01535-X     Document Type: Short Survey

References (1)

1. Rotella D.et al. N-3-substituted imidazoquinazolinones: potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction. J. Med. Chem. 43:2000;1257-1263.