Lactic acidosis and hepatic steatosis associated with use of stavudine: Report of four cases

Annals of Internal Medicine

Volumn 133, Issue 3, 2000, Pages 192-196

  Miller, K D ^a   Cameron, M ^a   Wood, L V ^a   Dalakas, M C ^a   Kovacs, J A ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; DIDANOSINE; INDINAVIR; LACTIC ACID; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; RITONAVIR; SAQUINAVIR; STAVUDINE; TRIACYLGLYCEROL LIPASE; ZIDOVUDINE;

ADOLESCENT; ADULT; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FATTY LIVER; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; INTENSIVE CARE; LACTIC ACIDOSIS; LIVER BIOPSY; MALE; MUSCLE BIOPSY; MYOPATHY; PRIORITY JOURNAL;

EID: 0034254566     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-133-3-200008010-00010     Document Type: Article

References (20)

1. Reye's syndrome in adult with AIDS
2. Chronic lactic acidosis in a patient with acquired immunodeficiency syndrome and mitochondrial myopathy: Biochemical studies
3. Lactic acidosis complicating the acquired immunodeficiency syndrome
4. A new syndrome of heaptomegaly with severe steatosis in HIV seropositive patients
5. Metabolic, hepatic and muscular changes during zidovudine therapy: A drug-induced mitochondrial disease?
6. Hepatic steatosis and lactic acidosis associated with stavudine treatment in an HIV patient: A case report
7. Riboflavin to treat nucleoside analogue-induced lactic acidosis
8. Drug interactions in patients infected with human immunodeficiency virus
9. Fulminant hepatitis with severe lactate acidosis in HIV-infected patients on didanosine therapy
10. Zidovudine-induced fatal lactic acidosis and hepatic failure in patients with acquired immunodeficiency syndrome: Report of two patients and review of the literature
11. Nonalcoholic steatohepatitis
12. Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion
13. Mitochondrial toxicity of antiviral drugs
14. Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as common pathway
15. Mitochondrial myopathy caused by long-term zidovudine therapy
16. Concurrent zidovudine-induced myopathy and hepato-toxicity in patients treated for human immunodeficiency virus (HIV) infection
17. Effect of anti-HIV 2'-beta-fluoro-2',3'-dideoxynucleoside analogs on the cellular content of mitochondrial DNA and on lactate production
18. Beri-Beri and thiamine deficiency in HIV infection
19. Thiamine for the treatment of nucleoside analogue-induced severe lactic acidosis
20. Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B