Simulation of axonal excitability using a Spreadsheet template created in Microsoft Excel

Computer Methods and Programs in Biomedicine

Volumn 63, Issue 1, 2000, Pages 47-54

  Brown, Angus M ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Axon; Hodgkin Huxley; Ion channel; Microsoft Excel; Modeling; Simulation; Spreadsheet

Indexed keywords

CELL MEMBRANES; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; IONS; PHYSIOLOGICAL MODELS; SPREADSHEETS;

AXON EXCITABILITY; ION CHANNEL; SOFTWARE PACKAGE EXCEL;

MEDICAL COMPUTING;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; GIANT AXON; IN VITRO STUDY; NERVE EXCITABILITY; NONHUMAN; SQUID;

EID: 0034254410     PISSN: 01692607     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-2607(00)00076-6     Document Type: Article

References (17)

1. A.M. Brown A methodology for simulating biological systems using Microsoft Excel Comp. Methods Prog. Biomed. 58 1999 181 190
2. A.L. Hodgkin A.F. Huxley A quantitative description of membrane current and its application to conduction and excitation in nerve J. Physiol. (Lond.) 117 1952 500 544
3. B. Hille Ionic basis of resting and action potentials E. Kandel Handbook of Physiology 1977 American Physiological Society Bethesda, MD 99 136
4. A.L. Hodgkin The ionic basis of electrical activity in nerve and muscle Biol. Rev. 26 1951 339 409
5. E.D. Adrian The Basis of Sensation 1928 Hafner New York
6. F.A. Dodge On the transduction of visual, mechanical, and chemical stimuli Int. J. Neurosci. 3 1972 5 14
7. B.I. Shapiro F.K. Lenherr Hodgkin–Huxley axon. Increased modulation and linearity of response to constant current stimulus Biophys. J. 12 1972 1145 1158
8. A.L. Hodgkin B. Katz The effect of sodium ions on the electrical activity of the giant axon of the squid J. Physiol. (Lond.) 108 1949 37 77
9. A.L. Hodgkin A.F. Huxley B. Katz Measurements of current–voltage relations in the membrane of the giant axon of Loligo J. Physiol. 116 1952 424 448
10. A.L. Hodgkin A.F. Huxley Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo J. Physiol. 116 1952 449 472
11. A.L. Hodgkin A.F. Huxley The components of membrane conductance in the giant axon of Loligo J. Physiol. 116 1952 473 496
12. A.L. Hodgkin A.F. Huxley The dual effects of membrane potential on sodium conductance in the giant axon of Loligo J. Physiol. 116 1952 497 506
13. B. Hille Ionic Channels of Excitable Membranes 1992 Sinauer Associates Inc Sunderland, MA
14. C.C. Canavier J.W. Clark J.H. Byrne Simulation of the bursting activity of neuron R15 in Aplysia : role of ionic currents, calcium balance, and modulatory transmitters J. Neurophysiol. 66 1991 2107 2124
15. P. Revest Neurosim for Windows Trends Neurosci. 18 1995 556
16. M.L. Hines N.T. Carnevale The NEURON simulation environment Neural Comput. 9 1997 1179 1209
17. J.M. Bower D. Beeman The Book of Genesis 1995 Springer Berlin