Flow cytometric differentiation of Asian and Western types of multiple sclerosis, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and hyperIgEaemic myelitis by analyses of memory CD4 positive T cell subsets and NK cell subsets

Journal of the Neurological Sciences

Volumn 177, Issue 1, 2000, Pages 24-31

  Wu, Xiao Mu ^a   Osoegawa, Manabu ^a   Yamasaki, Kenji ^a   Kawano, Yuji ^a   Ochi, Hirofumi ^a   Horiuchi, Izumi ^a   Minohara, Motozumi ^a   Ohyagi, Yasumasa ^a   Yamada, Takeshi ^a   Kira, Jun Ichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Flow cytometry; HTLV 1 associated myelopathy; IgE; Multiple sclerosis; Myelitis

Indexed keywords

CD16 ANTIGEN; CD3 ANTIGEN; CD30 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CYTOKINE; PADGEM PROTEIN;

ADULT; AGED; ARTICLE; BLOOD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; HUMAN; HYPERIMMUNOGLOBULINEMIA E; MEMORY CELL; MULTIPLE SCLEROSIS; MYELITIS; NATURAL KILLER CELL; PRIORITY JOURNAL; SPASTIC PARAPLEGIA; SPINAL CORD DISEASE; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ADULT; AGED; CD4-POSITIVE T-LYMPHOCYTES; CHEMOKINES; DIAGNOSIS, DIFFERENTIAL; FLOW CYTOMETRY; HUMANS; IMMUNITY, CELLULAR; KILLER CELLS, NATURAL; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELITIS; PARAPARESIS, TROPICAL SPASTIC; RECEPTORS, LYMPHOCYTE HOMING;

EID: 0034253940     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(00)00322-1     Document Type: Article

References (46)

1. Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell. 85:1996;299-302.
2. + lymphocytes in multiple sclerosis. J. Neurol. 239:1992;437-440.
3. Scolozzi R., Boccafogli A., Tola M.R., Vicentini L., Camerani A., Degani D., Granieri E., Caniatti L., Paolino E. T-cell phenotypic profiles in the cerebrospinal fluid and peripheral blood of multiple sclerosis patients. J. Neurol. Sci. 108:1992;93-98.
4. Strauss K., Hulstaert F., Deneys V., Mazzon A.M., Hannet I., De Bruyère M., Reichert T., Sindic C.J.M. The immune profile of multiple sclerosis: T-lymphocyte effects predominate over all other factors in cyclophosphamide-treated patients. J. Neuroimmunol. 63:1995;133-142.
5. + memory T lymphocytes in the peripheral blood of multiple sclerosis patients. Clin. Diagn. Lab. Immunol. 2:1995;249-252.
6. Vora A.J., Perkin G.D., McCoy T., Dumonde D.C., Brown K.A. Enhanced binding of lymphocytes from patients with multiple sclerosis to tumour necrosis factor-alpha (TNF-α)-treated endothelial monolayers: associations with clinical relapse and adhesion molecule expression. Clin. Exp. Immunol. 105:1996;155-162.
7. Munschauer F.E., Hartrich L.A., Stewart C.C., Jacobs L. Circulating natural killer cells but not cytotoxic T lymphocytes are reduced in patients with active relapsing multiple sclerosis and little clinical disability as compared to controls. J. Neuroimmunol. 62:1995;177-181.
8. Kuroda Y., Shibasaki H. Peripheral blood and CSF T-cell subsets in Japanese MS patients. Neurology. 35:1985;270-273.
9. Shibasaki H., McDonald W.I., Kuroiwa Y. Racial modification of clinical picture of multiple sclerosis: comparison between British and Japanese patients. J. Neurol. Sci. 49:1981;253-271.
10. Kira J., Kanai T., Nishimura Y., Yamasaki K., Matsushita S., Kawano Y., Hasuo K., Tobimatsu S., Kobayashi T. Western versus Asian types of multiple sclerosis: immunogenetically and clinically distinct disorders. Ann. Neurol. 40:1996;569-574.
11. Yamasaki K, Horiuchi I, Minohara M, Kawano Y, Ohyagi Y, Yamada T, Mihara F, Ito H, Nishimura Y, Kira J. HLA-DPB1*0501-associated optico-spinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies. Brain 1999 (in press).
12. Ono T., Zambenedetti M.R., Yamasaki K., Kawano Y., Kamikawaji N., Ito H., Sakurai M., Nishimura Y., Kira J., Kanazawa I., Sasazuki T. Molecular analysis of H.L.A. class I (HLA-A and -B) and HLA class II (HLA-DRB1) genes in Japanese patients with multiple sclerosis (Western type and Asian type). Tissue Antigens. 52:1998;539-542.
13. Olerup O., Hillert J. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens. 38:1991;1-15.
14. Ito H., Yamasaki K., Kawano Y., Horiuchi I., Yun C., Nishimura Y., Kira J. HLA-DP-associated susceptibility to the optico-spinal form of multiple sclerosis in the Japanese. Tissue Antigens. 52:1998;179-182.
15. Ma J.J., Nishimura M., Mine H., Saji H., Ohta M., Saida K., Ozawa K., Kawakami H., Saida T., Uchiyama T. HLA-DRB1 and tumor necrosis factor gene polymorphisms in Japanese patients with multiple sclerosis. J. Neuroimmunol. 92:1998;109-112.
16. Fukazawa T., Niino M., Yabe I., Kikuchi S., Yanagawa T., Hamada T., Tashiro K. Clinical and immunological heterogeneity in Japanese MS: distinct characteristics of MS showing acute transverse myelopathy and the optic-spinal form of MS, and heterogeneity of conventional MS. Neuroimmunology. 7:1999;16-17. (Japanese).
17. Inogés S., Merino J., Bandrés E., De Castro P., Subirá M.L., Sánchez-Ibarrola A. Cytokine flow cytometry differentiates the clinical status of multiple sclerosis (MS) patients. Clin. Exp. Immunol. 115:1999;521-525.
18. Horiuchi I., Kawano Y., Yamasaki K., Minohara M., Furue M., Taniwaki T., Miyazaki T., Kira J. Th1 dominance in HAM/TSP and the optico-spinal form of multiple sclerosis versus Th2 dominance in mite antigen-specific IgE myelitis. J. Neurol. Sci. 172:2000;17-24.
19. + T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions. Proc. Natl. Acad. Sci. USA. 96:1999;6873-6878.
20. Burns J., Bartholomew B., Lobo S. Isolation of myelin basic protein-specific T cells predominantly from the memory T cell compartment in multiple sclerosis. Ann. Neurol. 45:1999;33-39.
21. + T cells. Immunology. 87:1996;186-190.
22. Loetscher P., Uguccioni M., Bordoli L., Baggiolini M., Moser B., Chizzolini C., Dayer J.-M. CCR5 is characteristic of Th1 lymphocytes. Nature. 391:1998;344-345.
23. Bonecchi R., Bianchi G., Bordignon P.P., D’Ambrosio D., Lang R., Borsatti A., Sozzani S., Allavena P., Gray P.A., Mantovani A., Sinigaglia F. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 187:1998;129-134.
24. Siveke J.T., Hamann A. T helper 1 and T helper 2 cells respond differentially to chemokines. J. Immunol. 160:1998;550-554.
25. Mantovani A., Allavena P., Vecchi A., Sozzani S. Chemokines and chemokine receptors during activation and deactivation of monocytes and dendritic cells and in amplification of Th1 versus Th2 responses. Int. J. Clin. Lab. Res. 28:1998;77-82.
26. + T cells producing Th2-type cytokines. FASEB J. 9:1995;81-86.
27. pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 179:1994;1285-1295.
28. Prussin C., Foster B. TCR Vα24 and Vβ11 coexpression defines a human NK1 T cell analog containing a unique Th0 subpopulation. J. Immunol. 159:1997;5862-5870.
29. Wilson S.B., Kent S.C., Patton K.T., Orban T., Jackson R.A., Exley M., Porcelli S., Schatz D.A., Atkinson M.A., Balk S.P., Strominger J.L., Hafler D.A. Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes. Nature. 391:1998;177-181.
30. Iwasaki Y. Pathology of chronic myelopathy associated with HTLV-I infection (HAM/TSP). J. Neurol. Sci. 96:1990;103-123.
31. Kira J., Yamasaki K., Kawano Y., Kobayashi T. Acute myelitis associated with hyperIgEemia and atopic dermatitis. J. Neurol. Sci. 194:1997;199-203.
32. Kira J., Kawano Y., Yamasaki K., Tobimatsu S. Acute myelitis with hyperIgEaemia and mite antigen specific IgE: atopic myelitis. J. Neurol. Neurosurg. Psychiatry. 64:1998;676-679.
33. Kira J., Kawano Y., Horiuchi I., Yamada T., Imayama S., Furue M., Yamasaki K. Clinical, immunological and MRI features of myelitis with atopic dermatitis (atopic myelitis). J. Neurol. Sci. 162:1999;56-61.
34. Poser C.M., Paty D.W., Scheinberg L., McDonald W.I., Davis F.A., Ebers G.C., Johnson K.P., Sibley W.A., Silberberg D.H., Tourtellotte W.W. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 13:1983;227-231.
35. Osame M., Matsumoto M., Usuku K., Izumo S., Ijichi N., Amitani H., Tara M., Igata A. Chronic progressive myelopathy associated with elevated antibodies to human T lymphotropic virus type I and adult T cell leukemialike cells. Ann. Neurol. 21:1987;117-122.
36. + T cells via CD40 ligand. Proc. Natl. Acad. Sci. USA. 94:1997;599-603.
37. Mori M., Kinoshita K., Ban N., Yamada Y., Shiku H. Activated T lymphocytes with polyclonal gammopathy in patients with human T lymphotropic virus type I-associated myelopathy. Ann. Neurol. 24:1988;280-282.
38. Itoyama Y., Kira J., Fujii N., Goto I., Yamamoto N. Increases in helper inducer T cells and activated T cells in HTLV-I-associated myelopathy. Ann. Neurol. 26:1989;257-262.
39. Yu F., Itoyama Y., Fujihara K., Goto I. Natural killer (NK) cells in HTLV-I-associated myelopathy/tropical spastic paraparesis-decrease in NK cell subset populations and activity in HTLV-I seropositive individuals. J. Neuroimmunol. 33:1991;121-128.
40. Zhang B., Yamamura T., Kondo T., Fujiwara M., Tabira T. Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J. Exp. Med. 186:1997;1677-1687.
41. - T-cell deficiency and IDDM in NOD/Lt mice. Diabetes. 46:1997;572-582.
42. Nieda M., Nicol A., Koezuka Y., Kikuchi A., Takahashi T., Nakamura H., Furukawa H., Yabe T., Ishikawa Y., Tadokoro K., Juji T. Activation of human Vα24 NKT cells by α-glycosylceramide in a CD1d-restricted and Vα24TCR-mediated manner. Hum. Immunol. 60:1999;10-19.
43. Sumida T., Sakamoto A., Murata H., Makino Y., Takahashi H., Yoshida S., Nishioka K., Iwamoto I., Taniguchi M. Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis. J. Exp. Med. 182:1995;1163-1168.
44. Godoy A.J., Itoyama Y., Tokunaga K., Hara H., Kawaga Y., Kiyokawa H., Maeda Y., Goto I. Allolymphocytotoxic antibodies in sera from HTLV-I-associated myelopathy/tropical spastic paraparesis patients-putative anti-HLA antibodies. J. Neurol. Sci. 125:1994;62-69.
45. Nagai M., Yashiki S., Fujiyoshi T., Fujiyama C., Kitze B., Izumo S., Osame M., Sonoda S. Characterization of a unique T cell clone established from a patient with HAM/TSP which recognized HTLV-I-infected T cell antigens as well as spinal cord tissue antigens. J. Neuroimmunol. 65:1996;97-105.
46. Murai H., Kikuchi H., Osoegawa M., Takahashi H., Yamabe K., Iwaki T., Mizutani T., Oda M., Horiuchi I., Yamasaki K., Kira J. Biopsied spinal cord specimens show eosinophilic inflammation in atopic myelitis. Neuroimmunology. 8:2000;72-73.