ADPKD: A human disease altering golgi function and basolateral exocytosis in renal epithelia

Traffic

Volumn 1, Issue 8, 2000, Pages 675-686

  Charron, Audra J ^a   Bacallao, Robert L ^b   Wandinger Ness, Angela ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Autosomal dominant polycystic kidney disease; Epithelial cell; Polarity; post Golgi transport; Vesicular trafficking

Indexed keywords

G PROTEIN, VESICULAR STOMATITIS VIRUS; MEMBRANE PROTEIN; VIRUS ENVELOPE PROTEIN;

ARTICLE; CASE REPORT; CELL CULTURE; EPITHELIUM; EXOCYTOSIS; GOLGI COMPLEX; HUMAN; INTRACELLULAR MEMBRANE; KIDNEY POLYCYSTIC DISEASE; KIDNEY TUBULE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN TRANSPORT; TRANSPORT VESICLE; ULTRASTRUCTURE;

CELLS, CULTURED; EPITHELIUM; EXOCYTOSIS; GOLGI APPARATUS; HUMANS; INTRACELLULAR MEMBRANES; KIDNEY TUBULES; MEMBRANE GLYCOPROTEINS; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; PROTEIN TRANSPORT; TRANSPORT VESICLES; VIRAL ENVELOPE PROTEINS;

EID: 0034252898     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2000.010811.x     Document Type: Article

References (10)

1. Charron A, Nakamura S, Bacallao R, Wandinger-Ness A. Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells. J Cell Biol 2000;149: 111-124.
2. Consortium TEPKD. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell 1994;77: 881-894.
3. Consortium IPKD. Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. Cell 1995;81: 289-298.
4. Consortium TAP, Burn TC, Connors TD, Dackowski WR, Petry LR, Van RTJ, Millholland JM, Venet M. Miller G, Hakim RM, Landes GM, et al. Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat. The American PKD1 Consortium (APKD1 Consortium). Hum Mol Genet 1995;4: 575-582.
5. Hughes J, Ward CJ, Peral B, Aspinwall R, Clark K, San MJL, Gamble V, Harris PC. The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains. Nat Genet 1995;10: 151-160.
6. Reeders ST, Breuning MH, Davis KE, Nicholls R, Jarman A, Higgs D, Peerason P, Weatherall D. A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16. Nature 1985;317: 542-544.
7. van Adelsberg JS, Frank D. The PKD1 gene produces a developmentally regulated protein in mesenchyme and vasculature. Nat Med 1995;1: 359-364.
8. Ward CJ, Turley H, Ong AC, Comley M, Biddolph S, Chetty R, Ratcliffe PJ, Gattner K, Harris PC. Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney. Proc Natl Acad Sci USA 1996;93: 1524-1528.
9. Peters DJ, van de Wal A, Spruit L, Saris JJ, Breuning MH, Bruijn JA, de Heer E. Cellular localization and tissue distribution of polycystin-1. J Pathol 1999;188: 439-446.
10. Ibraghimov-Beskrovnaya O, Dackowski WR, Foggensteiner L, Coleman N, Thiru S, Petry LR, Burn TC, Connors TD, Van Raay T, Bradley J, Qian F, Onuchic LF, Watnick TJ, Piontek K, Hakim RM, Landes GM, Germino GG, Sandford R, Klinger KW. Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein. Proc Natl Acad Sci USA 1997;94: 6397-6402.