Acute Intermittent Porphyria: Expression of Mutant and Wild-Type Porphobilinogen Deaminase in COS-1 Cells

Molecular Medicine

Volumn 6, Issue 8, 2000, Pages 670-679

  Mustajoki, Sami ^a   Laine, Minna ^b   Lahtela, Maija ^c   Mustajoki, Pertti ^a   Peltonen, Leena ^b   Kauppinen, Raili ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c IT Center for Science   (Finland)

Author keywords

Acute Intermittent Porphyria; Cross reactive Immunological Material (CRIM); Detectable Polypeptide; Mutant Polypeptide; Porphobilinogen Deaminase

Indexed keywords

PORPHOBILINOGEN DEAMINASE; RECOMBINANT PROTEIN;

ACUTE INTERMITTENT PORPHYRIA; AMINO ACID SUBSTITUTION; ANIMAL; ARTICLE; CELL STRAIN COS1; CHEMICAL STRUCTURE; CHEMISTRY; CYTOPLASM; ENZYME STABILITY; ENZYMOLOGY; EXON; FLUORESCENT ANTIBODY TECHNIQUE; GENE DELETION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN CONFORMATION; STOP CODON; WESTERN BLOTTING;

AMINO ACID SUBSTITUTION; ANIMALS; BLOTTING, WESTERN; CODON, NONSENSE; COS CELLS; CYTOPLASM; ENZYME STABILITY; EXONS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYDROXYMETHYLBILANE SYNTHASE; MODELS, MOLECULAR; MUTATION; PORPHYRIA, ACUTE INTERMITTENT; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE DELETION; TRANSFECTION;

MLCS; MLOWN;

EID: 0034252468     PISSN: 10761551     EISSN: 15283658     Source Type: Journal    
DOI: 10.1007/BF03402047     Document Type: Article

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