Buccal absorption of triclosan following topical mouthrinse application

American Journal of Dentistry

Volumn 13, Issue 4, 2000, Pages 215-217

  Lin, Yi Jong ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONIDE; PLACEBO; SULFATE; TOPICAL ANTIINFECTIVE AGENT; TRICLOSAN;

ABSORPTION; ADOLESCENT; ADULT; ARTICLE; BLOOD; CHEMISTRY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FOLLOW UP; GINGIVA; HUMAN; MALE; METABOLISM; MOUTH HYGIENE; MOUTH MUCOSA; ORAL DRUG ADMINISTRATION; TOOTH PLAQUE;

ABSORPTION; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ANTI-INFECTIVE AGENTS, LOCAL; DENTAL PLAQUE; FOLLOW-UP STUDIES; GINGIVA; GLUCURONIDES; HUMANS; MALE; MOUTH MUCOSA; MOUTHWASHES; PLACEBOS; SULFATES; TRICLOSAN;

EID: 0034252378     PISSN: 08948275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Ciba-Gèigy Corporation technical bulletin: Irgasan DP 300. Broad spectrum antibacterial, 1988.
2. Regos J, Zak O, Solf R, et al. Antimicrobial spectrum of triclosan, a broad spectrum antimicrobial agent for topical application: II. Comparison with some other antimicrobial agents. Dermatologica 1979;158:72-79.
3. Saxton C A. The effects of a dentifrice containing zinc citrate and 2,4,4′ trichlors-2-hydroxydiphenyl ether. J Periodontol 1986;57:555-561.
4. Lindhe J. Triclosan/copolymer/fluoride dentifrice: A new technology for the prevention of plaque, calculus, gingivitis and caries. Am J Dent 1990; 3:53-54.
5. Volpe A R, Petrone M E, DeVizio W, et al. A review of plaque, calculus and caries studies with a dentifrice containing triclosan and PVM/MA copolymer. J Clin Dent 1993;4:31-41.
6. Ayad F, Berta R. Effect on plaque removal and gingivitis of a triclosancopolymer pre-brush rinse: A six-month clinical study in Canada. J Can Dent Assoc 1995;61:53-56.
7. Gaffar A, Afflitto J, Nabi N, et al. Recent advances in plaque, gingivitis, tartar and caries prevention technology. Int Dent J 1994; 44: 63-70.
8. Volpe A R, Petrone M E, DeVizio W, et al. A review of plaque, gingivitis, calculus and caries clinical efficacy studies with a fluoride dentifrice containing triclosan and PVM/MA copolymer. J Clin Dent 1996; 7: S1-S14.
9. Hagedorn-Leweke U, Lippold B C. Absorption of sunscreens and other compounds through human skin in vivo: Derivation of a method to predict maximum fluxes. Pharma Res 1995; 12: 1354-1360.
10. DeSalva S J, Kong B M, Lin Y-J. Triclosan: A safety profile. Am J Dent 1989, 2: 185-196.
11. Bodey G P, Arnett J, DeSalva S J. Comparative trial of bacteriostatic soap preparations: Hexachlorophene versus triclosan and triclocarbon. Cur Therap Res 1978; 24: 542-550.
12. Gilbert R J. The oral clearance of zinc and triclosan after delivery from a dentifrice. J Pharm Pharmacol 1986; 39: 480-483.
13. Gilbert R J, Fraser S B, Van der Ouderaa F J G. Oral disposition of triclosan delivered from a dentifrice. Caries Res 1987; 21: 29-36.
14. Gilbert R J, Williams P E O. The oral retention and antiplaque efficacy of triclosan in human volunteers. Br J Clin Pharmac 1987; 23: 579-583.
15. Afflitto J, Fakhry-Smith S, Gaffar A. Salivary and plaque triclosan levels after brushing with a 0.3% triclosan/copolymer/NaF dentifrice. Am J Dent 1989; 2: 207-210.
16. Quigley G A, Hein J W. Comparative cleansing efficacy of manual and power brushing. J. Am Dent Assoc 1962; 65: 26-29.
17. Turesky S, Gilmore N D, Glickman I. Reduced plaque formation by the chloromethyl analogue of Victamine C. J Periodontol 1970; 41: 41-43.
18. Concentration of triclosan, triclosan glucuronide and triclosan sulfate in human plasma samples, and concentration of total triclosan in human expectorate and plaque samples. Technical Report. Hazleton Wisconsin Inc., Study No. 6252-114, May 1, 1991.