The p53-independent tumoricidal activity of an adenoviral vector encoding a p27-p16 fusion tumor suppressor gene

Molecular Therapy

Volumn 2, Issue 2, 2000, Pages 161-169

  Patel, Salil D ^a   Tran, Annie C ^a   Ge, Ying ^a   Moskalenko, Marina ^a   Tsui, Lisa ^a   Banik, Gautam ^a   Tom, Warren ^a   Scott, Michael ^a   Chen, Lili ^a   Van Roey, Melinda ^a   Rivkin, Marianne ^a   Mendez, Michael ^a   Gyuris, Jeno ^b   McArthur, James G ^a  

^a CELL GENESYS INC   (United States)

^b GPC Biotech Inc   (United States)

Author keywords

Adenovirus cancer gene therapy; Antiangiogenic; p16; p27

Indexed keywords

ADENOVIRIDAE; MURINAE;

CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; HYBRID PROTEIN; LIPOCORTIN 5; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN P16INK4A; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ADENOVIRUS; ANIMAL; AORTA; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; CELL CULTURE; CELL LINE; CELL SEPARATION; FLOW CYTOMETRY; GENE THERAPY; GENE VECTOR; GENETICS; HUMAN; METABOLISM; MOUSE; NEOPLASM; NICK END LABELING; TIME; TUMOR SUPPRESSOR GENE;

ADENOVIRIDAE; ANIMALS; ANNEXIN A5; AORTA; APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE; CELL SEPARATION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FLOW CYTOMETRY; GENE THERAPY; GENES, P53; GENES, TUMOR SUPPRESSOR; GENETIC VECTORS; HUMANS; IN SITU NICK-END LABELING; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASMS; RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA PROTEIN; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0034244657     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0106     Document Type: Article

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