The rôle of time in reducing gingival overgrowth in heart-transplanted patients following cyclosporin therapy

Journal of Clinical Periodontology

Volumn 27, Issue 8, 2000, Pages 611-614

  Montebugnoli, Lucio ^a   Servidio, Dora ^a   Bernardi, Federico ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Cyclosporin; Gingival overgrowth; Heart transplantation

Indexed keywords

CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; CHI SQUARE DISTRIBUTION; FEMALE; GINGIVA OVERGROWTH; HEART TRANSPLANTATION; HOSPITALIZATION; HUMAN; MALE; NONPARAMETRIC TEST; PATHOLOGY; PATHOPHYSIOLOGY; PERIODONTICS; REGRESSION ANALYSIS; REMISSION; TIME; TOOTH PLAQUE;

ADULT; ANALYSIS OF VARIANCE; CHI-SQUARE DISTRIBUTION; CYCLOSPORINE; DENTAL PLAQUE INDEX; FEMALE; GINGIVAL OVERGROWTH; HEART TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; PERIODONTAL INDEX; REGRESSION ANALYSIS; REMISSION, SPONTANEOUS; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 0034241377     PISSN: 03036979     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-051x.2000.027008611.x     Document Type: Article

References (14)

1. Allman, S. D., McWhorter, A. G. & Seale, N. S. (1994) Evaluation of cyclosporin-induced gingival overgrowth in the pediatric transplant patient. Pediatric Dentistry 16, 36-40.
2. Hefti, A. F., Eshenaur, A. E., Hassell, T. M. & Stone C. (1994) Gingival overgrowth in cyclosporine A treated multiple sclerosis patients. Journal of Periodontology 65, 744-749.
3. King, G. N., Fullinfaw, R., Higgins, T. J., Walker, R. G., Francis, D. M. A. & Wiesenfeld, D. (1993) Gingival hyperplasia in renal allograft recipients receiving cyclosporin-a and calcium antagonists. Journal of Clinical Periodontology 20, 286-293.
4. McGaw, T., Lam, S. & Soates, J. (1987) Cyclosporin-induced gingival overgrowth: correlation with dental plaque scores, gingivitis scores, and cyclosporin levels in serum and saliva. Oral Surgery Oral Medicine Oral Pathology 64, 293-297.
5. Montebugnoli, L., Bernardi, F. & Magelli, C. (1996) Cyclosporin-A-induced gingival overgrowth in heart transplant patients: a cross-sectional study. Journal of Clinical Periodontology 23, 868-872.
6. Montebugnoli, L. & Bernardi, F. (1999) Cyclosporin A effects on extraoral connective tissue in heart transplanted patients. Journal of the International Academy of Periodontology 3, 91-94.
7. Seymour, R. A. & Smith, D. G. (1991) The effect of a plaque control programme on the incidence and severity of cyclosporin-induced gingival changes. Journal of Clinical Periodontology 18, 107-110.
8. Seymour, R. A., Thomason, J. M. & Ellis, J. S. (1996) The pathogenesis of drug-induced gingival overgrowth. Journal of Clinical Periodontology 23, 165-175.
9. Somacarrera, M. L., Hernandez G., Acero J. & Moskow, B. S. (1994) Factors related to the incidence and severity of cyclosporin-induced gingival overgrowth in transplant patients. A longitudinal study. Journal of Periodontology 65, 671-675.
10. Somacarrera, M. L., Lucas M., Scully, C. & Barrios, C. (1997) Effectiveness of periodontal treatments on cyclosporine-induced gingival overgrowth in transplant patients. Brithis Dental Journal 183, 89-94.
11. Spratt, H., Boomer, S., Irwin, C. R., Marley, J. J., James, J. A., Maxwell, P., Middleton, D. & Linden, G. J. (1999) Cyclosporin associated gingival overgrowth in renal transplant recipients. Oral Diseases 5, 27-31.
12. Thomason, J. M., Seymour, R. A. & Rice, N. (1993) The prevalence and severity of cyclosporin and nifedipine-induced gingival overgrowth. Journal of Clinical Periodontology 20, 37-40.
13. Wilson, R., Morel, A. & Smith, D. (1998) Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy. Journal of Clinical Periodontology 25, 457-464.
14. Wondimu, B., Dahllof, G., Berg, U. & Modeer, T. (1997) Cyclosporin A upregolates prostaglandin E2 production in human gigngival fibroblasts challenged with tumor necrosis factor alpha in vitro. Journal of Oral, Pathology and Medicine 26, 11-16.