Inactivation of the ypaa gene in bacillus subtilis; analysis of the resulting phenotypic expression

Genetika

Volumn 36, Issue 8, 2000, Pages 1166-1168

  Kreneva, R A ^a  

^a PETERSBURG NUCLEAR PHYSICS INSTITUTE   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOFLAVIN;

ARTICLE; BACILLUS SUBTILIS; BIOSYNTHESIS; GENE SILENCING; GENETICS; METABOLISM; PHENOTYPE; TRANSPORT AT THE CELLULAR LEVEL;

BACILLUS SUBTILIS; BIOLOGICAL TRANSPORT; GENE SILENCING; PHENOTYPE; RIBOFLAVIN;

EID: 0034241199     PISSN: 00166758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Perkins J.B., Pero J.G. Biosynthesis of riboflavin, biotin, folic acid and cobalamin //Bacillus subtilis and other gram-positive bacteria/Eds Sonenshein A.L., Hoch J.A., Losick R. Washington: Amer. Soc. Microbiol., 1993. P. 319-334.
2. Solovieva IM., Kreneva R.A., Leak D.J., Perumov DA. The ribR gene encodes a monofunctional riboflavin kinase which is involved in regulation of the Bacillus subtilis riboflavin operon // Microbiology. 1999. V. 145. N° 1. P. 67-73.
3. Kunst F., Ogasavara N., Moszer 1. et al. The complete genome sequence of the Gram-posutive bacterium Bacillus subtilis II Nature. 1997. V. 390. P. 249-256.
4. Cecchini G., Perl M., Lipsick J. et al. Transport and binding of riboflavin by Bacillus subtilis II J. Biol. Chem. 1979. V. 254. JNs 15. P. 7295-7301.
5. Mack M., van Loon A.P.G.M., Hohman H.P. Regulation of riboflavin biosynthesis in Bac. subtilis is affected by the activity of the flavokinase/FAD-synthetase encoded by ribCin. Bacteriol. 1998. V. 180. N° 4. P. 950-955.
6. Gelfand M.S., Mironov A.A., Jomantas J. et al. A conserved RNA structure element involved in the regulation of bacterial riboflavin synthesis genes // Trends in Genetics. 1999. V. 15. K 11. P. 439-442.
7. Kreneva R.A., Perumov DA. Genetic mapping of regulatory mutations of Bacillus subtilis riboflavin operon // Mol. Gen. Genet. 1990. V. 222. P. 46769.
8. Kil Y.V., Mironov V.N., Goryshin I.Y. et al. Riboflavin operon in Bacillus subtilis: unusual symmetric arrangement of the regulatory region // Mol. Gen. Genet. 1992. V. 233. P. 483-486.
9. Saito H., Miura K.I. Preparation of transforming DNA by phenol treatment // Biochim. Biophys. Acta. 1963. V.42. P. 619-629.
10. Kearney E.B., Goldenberg J., Lipsick J. Flavokinase and FAD-synthetase from Bacillus subtilis specific for reduced flavins // J. Biol. Chem. 1979. V. 254. N° 5. P. 9551-9557.
11. Mironov V.N., Kraev A.S., Chikindas M.L. et al. Functional organization of the riboflavin biosynthesis operon from Bacillus subtilis SHgw // Mol. Gen. Genet. 1994. V. 242. P. 201-208.
12. Shavlovsky G.M., Sibirny A.A. Riboflavin transport in yeast and its regulation // Enviromental regulation of microbial metabolism / Eds Kulaev I.S., Dawes E.A., Tempest D.W. L.: Acad. Press, 1985. P. 385-392.
13. Forster C., Santas MA., Ruffert S., Revuelta J.L. Physiological consequence of disruption of the VMA1 gene in the riboflavin overproducer Ashbya gossypii // J. Biol. Chem. 1999. V. 274. N° 14. P. 9442-9448.