1H and 13C NMR study of the antihypertensive drugs nifedipine, nicardipine and related compounds

Magnetic Resonance in Chemistry

Volumn 38, Issue 8, 2000, Pages 680-683

  Morales Ríos, Martha S ^a   De La Cerda Medina, Alejandra ^a   Pérez Alvarez, Victor ^a   Joseph Nathan, Pedro ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

13C NMR; 1H NMR; Chiroptical nitrogen atom; Nicardipine; Nifedipine; NMR

Indexed keywords

CARBOXYLIC ACIDS; CHLORINE COMPOUNDS; NITROGEN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

13C NMR; 1H NMR; ANTIHYPERTENSIVE DRUGS; CHIROPTICAL NITROGEN ATOM; NICARDIPINE; NIFEDIPINE; NITROGEN ATOM; NMR STUDIES; RELATED COMPOUNDS; TWO-DIMENSIONAL;

PYRIDINE;

EID: 0034239624     PISSN: 07491581     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-458x(200008)38:8<680::aid-mrc679>3.0.co;2-b     Document Type: Article

References (21)

1. 1. Rampe D, Triggle DJ. Prog. Drug Res. 1993; 40: 191.
2. 2. Janis RA, Silver PJ, Triggle DJ. J. Adv. Drug. Res. 1987; 16: 309.
3. 3. Calzolai L, Gaggelli E, Maccotta A, Valensin G. J. Chem. Soc., Perkin Trans. 2 1997; 367.
4. 4. Belciug M-P, Ananthanarayanan VS. J. Med. Chem. 1994; 37: 4392.
5. 5. Gaggelli E, Marchettini N, Valensin G. J. Chem. Soc., Perkin Trans. 2 1987; 1707.
6. 6. Shibanuma T, Iwanani M, Okuda K, Takenaka T, Murakami M. Chem. Pharm. Bull. 1980; 28: 2809.
7. 7. Bax A, Morris GA. J. Magn. Reson. 1981; 42: 501.
8. 8. Reynolds WF, McLean S, Perpick-Dumont M, Enríquez RG. Magn. Reson. Chem. 1989; 27: 162.
9. 9. Mareci TH, Freeman R. J. Magn. Reson. 1982; 48: 158.
10. 10. Joseph-Nathan P, del Río RE, Morales-Ríos MS. Heterocycles 1988; 27: 377.
11. 11. Hansen PE. Annu. Rep. NMR Spectrosc. 1983; 15: 105.
12. 12. Morales-Ríos MS, Suárez-Castillo OR, Alvarez-Cisneros C, Joseph-Nathan P. Can. J. Chem. 1999; 77: 130.
13. 13. Closs GL. J. Chem. Soc. 1959; 81: 5456.
14. 14. For reviews, see (a) Rauk A, Allen LC, Mislow K. Angew. Chem., Int. Ed. Engl. 1970; 9: 400;
15. (b) Lehn JM. Fortschr. Chem. Forsch. 1970; 15: 311; Lambert JB. Top. Stereochem. 1971; 6: 19.
16. (b) Lehn JM. Fortschr. Chem. Forsch. 1970; 15: 311; Lambert JB. Top. Stereochem. 1971; 6: 19.
17. 15. Lambert JB, Takeuchi Y. Acyclic Organonitrogen Stereodynamics. VCH: New York, 1992.
18. 16. Loev B, Goodman MM, Snader KM, Tedeschi R, Macko E. J. Med. Chem. 1974; 17: 956.
19. 17. Coburn RA, Wierzba M, Suto MJ, Solo AJ, Triggle AM, Triggle DJ. J. Med. Chem. 1988; 31: 2103.
20. 18. Shibanuma T, Iwanani M, Okuda K, Takenaka T, Murakami M. Chem. Pharm. Bull. 1980; 28: 2809.
21. 19. Iwanami M, Shibanuma T, Fujimoto M, Kawai R, Tamazawa K, Takenaka T, Takahashi K, Murakami M. Chem. Pharm. Bull. 1979; 27: 1426.