Influence of matrix activation and polymer coating on the purification of human IgG with protein A affinity membranes

Journal of Membrane Science

Volumn 172, Issue 1-2, 2000, Pages 269-277

  Castilho, Leda R ^a   Deckwer, Wolf Dieter ^a   Anspach, F Birger ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Affinity membranes; Human immunoglobulin; Hydrophilic coating; Protein A; Protein adsorption

Indexed keywords

ADSORPTION; ANTIBODIES; CHROMATOGRAPHIC ANALYSIS; MICROFILTRATION; NYLON POLYMERS; PLASTIC COATINGS; POLYSACCHARIDES; POLYVINYL ALCOHOLS; PROTEINS; PURIFICATION;

AFFINITY MEMBRANES; IMMUNOGLOBULINS; PROTEIN ADSORPTION;

POLYMERIC MEMBRANES;

DEXTRAN; IMMUNOGLOBULIN G; POLYMER; POLYVINYL ALCOHOL; PROTEIN A;

ADSORPTION; MICROFILTRATION; NYLON; POLYMER COATING; PROTEIN; PURIFICATION;

ADSORPTION; ARTICLE; CHEMICAL MODIFICATION; FREEZING; HYDROLYSIS; HYDROPHILICITY; MEMBRANE PERMEABILITY; MEMBRANE STRUCTURE; MICROFILTRATION; PRIORITY JOURNAL; PURIFICATION; TEMPERATURE;

EID: 0034237139     PISSN: 03767388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-7388(00)00343-4     Document Type: Article

References (23)

1. Thömmes J., Bader A., Halfar M., Karau A., Kula M.R. Isolation of monoclonal antibodies from cell containing hybridoma broth using a protein A coated adsorbent in expanded beds. J. Chromatogr. A. 752:1996;111.
2. Brandt S., Goffe R.A., Kessler S.B., O'Connor J.L., Zale S.E. Membrane-based affinity technology for commercial scale purifications. Biotechnology. 6:1988;779.
3. Thömmes J., Kula M.R. Membrane chromatography - an integrative concept in the downstream processing of proteins. Biotechnol. Prog. 11:1995;357.
4. E. Klein, Affinity Membranes - Their Chemistry and Performance in Adsorptive Separation Processes, Wiley, New York, 1991.
5. Charcosset C. Purification of proteins by membrane chromatography. J. Chem. Technol. Biotechnol. 71:1998;95.
6. Beeskow T.C., Kusharyoto W., Anspach F.B., Kroner K.H., Deckwer W.D. Surface modification of microporous polyamide membranes with hydroxyethylcellulose and their application as affinity membranes. J. Chromatogr. A. 715:1995;49.
7. Beeskow T.C., Kroner K.H., Anspach F.B. Nylon-based affinity membranes: impacts of surface modification on protein adsorption. J. Colloid Interface Sci. 196:1997;278.
8. Santarelli X., Muller D., Jozefonvicz J. Dextran-coated silica packings for high-performance size-exclusion chromatography of proteins. J. Chromatogr. 443:1988;55.
9. Zhou F.L., Muller D., Jozefonvicz J. Double-coated silica packings for high-performance affinity chromatography of proteins. J. Chromatogr. 510:1990;71.
10. Mueller-Schulte D., Manjini S., Vijayalakshmi M.A. Comparative affinity chromatography studies using novel grafted polyamide and poly(vinyl alcohol) media. J. Chromatogr. 539:1991;307.
11. G.T. Hermanson, A.K. Mallia, P.K. Smith, Immobilized Affinity Ligand Techniques, Academic Press, San Diego, 1992.
12. Langmuir I. The adsorption of gases on plane surfaces of glass, mica and platinum. J. Am. Chem. Soc. 40:1918;1361.
13. 1 on group specific affinity sorbents. Bioseparation. 6:1996;165.
14. Biesheuvel P.M., Verweij H. Design of ceramic membrane supports: permeability, tensile strength and stress. J. Membr. Sci. 156:1999;141.
15. Koros W.J., Ma Y.H., Shimidzu T. Terminology for membranes and membrane processes. J. Membr. Sci. 120:1996;149.
16. Chu T.J., Yang M.H. Hydraulic permeation of water through heat-treated PVA membrane. J. Chem. Eng. Jpn. 25:1992;660.
17. Charcosset C., Su Z., Karoor S., Daun G., Colton C.K. Protein A immunoaffinity hollow fiber membranes for immunoglobulin G purification: experimental characterization. Biotechnol. Bioeng. 48:1995;415.
18. Dancette O.P., Taboureau J.L., Tournier E., Charcosset C., Blond P. Purification of immunoglobulin G by protein A/G affinity membrane chromatography. J. Chromatogr. B. 723:1999;61.
19. Klein E., Eichholz E., Theimer F., Yeager D. Chitosan modified sulfonated poly(ethersulfone) as a support for affinity separations. J. Membr. Sci. 95:1994;199.
20. Arnold F.H., Blanch H.W., Wilke C.R. Analysis of affinity separations I. Predicting the performance of affinity adsorbers. Chem. Eng. J. 30:1985;9.
21. Ohlson S., Bergstrom M., Pahlsson P., Lundblad A. Use of monoclonal antibodies for weak affinity chromatography. J. Chromatogr. A. 758:1997;199.
22. T.C. Beeskow, Chemische Oberflächenmodifizierung von Nylon-Mikrofiltrationsmembranen und deren Einsatz zur selektiven Proteinadsorption, Ph.D. Thesis, Technical University of Braunschweig, Germany, 1996.
23. Jönsson C., Jönsson A.S. Influence of the membrane material on the adsorptive fouling of ultrafiltration membranes. J. Membr. Sci. 108:1995;79.