Advanced glycosylation end products increase diacylglycerol levels in cultured human umbilical vein endothelial cells

Chinese Medical Journal

Volumn 113, Issue 7, 2000, Pages 588-591

  Yan, Jinchuan ^a   Liu, Naifeng ^a,b  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

Advanced glycosylation end products; Atherosclerosis; Diglycerides; Endothelial cells; Guanidines; Signal transduction; Vitamin E

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALPHA TOCOPHEROL; DIACYLGLYCEROL;

ARTICLE; CYTOLOGY; HUMAN; METABOLISM; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

DIGLYCERIDES; ENDOTHELIUM, VASCULAR; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; UMBILICAL VEINS; VITAMIN E;

EID: 0034236498     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Brownlee M. Advanced protein glycosylation in diabetes and aging. Annu Rev Med 1995;46:223-234.
2. Kume S, Takeya M, Mori T, et al. Immunohistochemical and ultrastructural detection of advanced glycation end products in atherosclerotic lesions of human aorta using a novel specific monoclonal antibody. Am J Pathol 1995;147:654-667.
3. Higashi T, Sano H, Saishoji T, et al. The receptors for advanced glycation end products mediate the chemotaxis of rabbit smooth muscle cells. Diabetes 1997;46:463-472.
4. Esposito C, Gerlach H, Brett J, et al. Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties. J Exp Med 1989;170:1387-1407.
5. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959;37:911-917.
6. Preiss J, and C, Loomis. Quantitative measurement of sn 1,2 diacylglycerol. Methods Enzymol 1987;141:294-300.
7. Sunako M, Kawahara Y, Hirata K, et al. Mass analysis of 1, 2-diacylglycerol in cultured rabbit vascular smooth muscle cells. Hypertension 1990;15:84-88.
8. Kikkawa, UA, Kishimoto, and Y, Nishizuka. The protein kinase C family: heterogeneity and its implications. Annu Rev Biochem 1989;58:31-44.
9. Jin H, Liu NF, Tang R. Effects of advanced glycosylation end products on proliferation and cytosolic free calcium in cultured rat aortic smooth muscle cells. Acta Pharmacol Sin 1997;18:422-425.
10. Zhou QG, Liu NF, Xie PL. Expression of receptor for advanced glycosylation end products and inhibition of AGEP-induced cytosolic calcium elevation by diltiazem in cultured rat aortic smooth muscle cells. Acta Pharmacol Sin 1997;18:425-430.
11. Kunisaki M, Fumio U, Nawata H, King GL. Vitamin E normalizes diacylglycerol-protein kinase C activation induced by hyperglycemia in rat vascular tissues. Diabetes 1996;45 ( Suppl 3 ): s117-s119.
12. Tran K, Proulx PR, Chan AC. Vitamin E suppresses diacylglycerol ( DAG ) level in thrombin-stimulated endothelial cells through an increase of DAG kinase activity. Biochim Biophys Acta 1994;1212:193-202.
13. Brownlee M. Glycation and diabetic complications. Diabetes 1994;43:836-841.
14. Chen HJ, Cerami A. Mechanism of inhibition of advanced glycosylation by aminoguanidine in vitro. J Carbohydr Chem 1993;12: 732-742.