Ex vivo cardiac allograft preservation by continuous perfusion techniques

ASAIO Journal

Volumn 46, Issue 4, 2000, Pages 389-396

  Smulowitz, Peter B ^a   Serna, Dan L ^a   Beckham, Gerald E ^a   Milliken, Jeffrey C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR SURGERY; CELLS; HYPOTHERMIA; METABOLISM; NUTRITION; OXYGEN; SUBSTRATES; TISSUE; TRANSPLANTATION (SURGICAL);

CARDIAC ALLOGRAFT PRESERVATION; CLINICAL TRANSPLANTATION; CONTINUOUS PERFUSION TECHNIQUE; CORONARY ARTERY PERFUSION; HYPOTHERMIC IMMERSION; MYOCARDIAL CELL;

BIOLOGICAL MATERIALS PRESERVATION;

ALBUMIN; BLOOD SUBSTITUTE; CALCIUM; CARDIOPLEGIC AGENT; LIDOCAINE; MAGNESIUM; POTASSIUM; PRESERVATION SOLUTION; VASODILATOR AGENT;

ACID BASE BALANCE; ANAEROBIC METABOLISM; ARTICLE; CARDIOPLEGIA; CORONARY ARTERY BLOOD FLOW; EDEMA; GRAFT PRESERVATION; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HEART PROTECTION; HEART TRANSPLANTATION; HUMAN; IMMERSION; NONHUMAN; NUTRITIONAL SUPPORT; ONCOTIC PRESSURE; OSMOLALITY; OXYGEN TISSUE LEVEL; PERFUSION PRESSURE; REPERFUSION INJURY; TEMPERATURE;

EID: 0034235534     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002480-200007000-00004     Document Type: Article

References (73)

1. Ferrera R, Marcsek P, Larese A, et al: Comparison of continuous microperfusion and cold storage for pig heart preservation. J Heart Lung Transplant 12: 463-469, 1993.
2. Proctor E, Parker R: Preservation of isolated heart for 72 hours. Br Med J 4: 296-298, 1968.
3. Gohra H, Mori F, Esato K: The effect of fluorocarbon emulsion on 24-hour canine heart preservation by coronary perfusion. Ann Thorac Surg 48: 96-103, 1989.
4. Wicomb W, Boyd ST, Cooper DK, Rose AG, Barnard CN: Ex vivo functional evaluation of pig hearts subjected to 24 hours' preservation by hypothermic perfusion. S Afr Med J 60: 245-248, 1981.
5. Levy JF, Bernard HR, Monafo WF: Isolation and storage of artificially oxygenated mammalian hearts. JAMA 191: 1006, 1965.
6. Manax WG, Largiader F, Lillehei RC: Whole canine organ preservation: Prolongation in vitro by hypothermia and hyperbaria. JAMA 196: 1121-1124, 1966.
7. Wicomb W, Cooper DK, Hassoulas J, Rose AG, Barnard CN: Orthotopic transplantation of the baboon heart after 20 to 24 hours' preservation by continuous hypothermic perfusion with an oxygenated hyperosmolar solution. J Thorac Cardiovasc Surg 82: 133-140, 1982.
8. Wicomb WN, Cooper DK, Novitsky D, Barnard CN: Cardiac transplantation following storage of the donor heart by a portable hypothermic perfusion system. Ann Thorac Surg 37: 243-248, 1984.
9. Wicomb WN, Cooper DK, Barnard CN: Twenty-four hour preservation of the pig heart by a portable perfusion system. Transplantation 34: 246-250, 1982.
10. Spray TL, Watson DC, Roberts WC: Morphology of canine hearts after 24 hours' preservation and orthotopic transplantation. J Thorac Cardiovasc Surg 73: 880-886, 1960.
11. Kioka Y, Tago M, Bando K, et al: Twenty-four hour isolated heart preservation by perfused method with oxygenated solution containing perfluorochemicals and albumin. J Heart Transplant 5: 437-443, 1986.
12. Ohtaki A, Ogiwara H, Kazuhiro S, Takahashi T, Morishita Y: Long-term heart preservation by the combined method of simple immersion and coronary perfusion. J Heart Lung Transplant 15: 269-274, 1996.
13. Calhoon JH, Bunegin L, Gelineau JF, et al: Twelve-hour canine heart preservation with a simple, portable, hypothermic organ perfusion device. Ann Thorac Surg 62: 91-93, 1996.
14. Nickless DK, Rabinov M, Richards SM, Conyers RAJ, Rosenfeldt FL: Continuous perfusion improves preservation of donor rat hearts: Importance of the implantation phase. Ann Thorac Surg 65: 1255-1272, 1998.
15. Hassanein WH, Zellos L, Tyrrell TA, et al: Continuous perfusion of donor hearts in the beating state extends preservation time and improves recovery of function. J Thorac Cardiovasc Surg 116: 821-830, 1998.
16. Grinyo JM. Reperfusion injury: Transplant Proc 29: 59-62, 1997.
17. Land W, Schneeberger H, Schleibner S, et al: The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants. Transplantation 57: 211-217, 1994.
18. Nicolini FA, Metha JL, Nichols WW, Donnelly WH, Luostarinen R, Saldeen TG: Leukocyte elastase inhibition and t-PA-induced coronary artery thrombolysis in dogs: Beneficial effects on myocardial histology. Am Heart J 122: 1245-1251, 1991.
19. w-Nitro-L-Arginine methyl ester on cardiac perfusion and function after 1-day cold preservation of isolated hearts. Circulation 95: 1623-1634, 1997.
20. Mankad P, Magdi Y: Influence of basal release of nitric oxide on systolic and diastolic function of both ventricles. J Thorac Cardiovasc Surg 113: 770-776, 1997.
21. Ohkado A, Cao-Danh H, Sommers KE, del Nido PJ: Evaluation of highly buffered low-calcium solution for long-term preservation of the heart: Comparison with University of Wisconsin solution (Abstract). J Thorac Cardiovasc Surg 108: 762-771, 1994.
22. Kober IM, Obermayr RP, Spieckermann PG: How beneficial is the reduction of edema formation by polyethylene glycol during cardioplegic arrest? Transplant Proc 28: 160-162, 1996.
23. Chambers DJ, Takahashi A, Hearse DJ: Long-term preservation of the heart: The effect of infusion pressure during continuous hypothermic cardioplegia. J Heart Lung Transplant 11: 665-675, 1992.
24. Rubboli A, Sobotka PA, Euler DE: Effect of acute edema on left ventricular function and coronary vascular resistance in the isolated rat heart. Am J Physiol 267: H1054-H1061, 1994.
25. Avkiran M, Hearse DJ: Protection of the myocardium during global ischemia: Is crystalloid cardioplegia effective in the immature myocardium? J Thorac Cardiovasc Surg 97: 220-228, 1989.
26. Shimada Y, Yamamoto F, Yamamoto H, Oka T, Kawashima Y: Temperature-dependent cardioprotection of exogenous substrates in long-term heart preservation with continuous perfusion: Twenty-four hour preservation of isolated rat heart with St. Thomas' Hospital solution containing glucose, insulin, and aspartate. J Heart Lung Transplant 15: 485-495, 1996.
27. Segel LD, Minten JMO, Schweighardt FK: Fluorochemical emulsion APE-LM substantially improves cardiac preservation. Am J Physiol 263: H730-H739, 1992.
28. Belzer FO, Southard JH: Principles of solid-organ preservation by cold storage. Transplantation 45: 673-676, 1988.
29. Segel LD, Follete DM, Baker JM, Rintoul TC: Recovery of sheep hearts after perfusion preservation or static storage with crystalloid media. J Heart Lung Transplant 17: 211-221, 1998.
30. Yee ES, Ebert PA: Effect of ischemia on ventricular function, compliance, and edema in immature and adult canine hearts. Surg Forum 30: 250-252, 1979.
31. Buckberg GD: A proposed "solution" to the cardioplegic controversy. J Thorac Cardiovasc Surg 77: 803-815, 1979.
32. Henry PD, Shuchleib R, Davis J, Weiss ES, Sobel BE: Myocardial contracture and accumulation of mitochondrial calcium in ischemic rabbit heart. Am J Physiol 233: H677-H684, 1977.
33. Nishioka K, Nakanishi T, Jarmakani JM: Effect of ischemia on calcium exchange in the rabbit myocardium. Am J Physiol 247: H177-H184, 1984.
34. Nayler WG: Protection of the myocardium against postischemic reperfusion damage: The combined effect of hypothermia and nifedipine. J Thorac Cardiovasc Surg 84: 897-905, 1982.
35. Corno A, Bethencourt DM, Laks H, et al: Myocardial protection in the neonatal heart. J Thorac Cardiovasc Surg 93: 163-172, 1987.
36. Bonfim V, Kaiser L, Bendz R, Sylven C, Olin C: Myocardial protection during aortic valve replacement. Scand J Thorac Cardiovasc Surg 15: 129-133, 1981.
37. Hearse DJ, Stewart DA, Braimbridge MV: Myocardial protection during ischemic cardiac arrest. Possible deleterious effects of glucose and mannitol in coronary infusates. J Thorac Cardiovasc Surg 76: 16-23, 1978.
38. Schaff HV, Goldman RA, Bulkley BH, Gott VL, Flaherty JT: Hyperosmolar reperfusion following ischemic cardiac arrest. Surgery 89: 141-150, 1981.
39. Crawford FA, Barnes TY, Heath BJ: Potassium-induced cardioplegia in patients undergoing correction of congenital heart defects. Chest 78: 13-26, 1980.
40. Preusse CJ, Schulte HD, Bircks W: High volume cardioplegia. Ann Chir Gynaecol 76: 39-45, 1987.
41. Langer GA: The effect of pH on cellular and membrane calcium binding and contraction of myocardium. Circ Res 57: 374-382, 1985.
42. Cingolani HE, Mattiazzi AR, Blesa ES, Gonzalez NC: Contractility in isolated mammalian heart muscle after acid-base changes. Circ Res 26: 269-278, 1970.
43. Ng ML, Levy MN, Zieske HA: Effects of changes of pH and of carbon dioxide tension on left ventricular performance. Am J Physiol 213: 115-120, 1967.
44. Schwalb H, Grinberg L, Yaroslavsky-Houminer E, et al: New solution for prolonged myocardial preservation for transplantation. J Heart Lung Transplant 17: 222-229, 1998.
45. Thomas FT, Schatzki PF, Hudson BH, Wolf JS: Successful 24-hour ischemic cardiac preservation using a new hyperosmolar perfusate. Surg Forum 26: 253-255, 1975.
46. +) solution and hypothermia. Surg Forum 25: 149-151, 1974.
47. Rich TL, Brady AJ: Potassium contracture and utilization of high-energy phosphates in the rabbit heart. Am J Physiol 226: 105-113, 1974.
48. Kronon M, Boiling KS, Allen BS, et al: The relationship between calcium and magnesium in pediatric myocardial protection. J Thorac Cardiovasc Surg 114: 1010-1019, 1997.
49. Aoki M, Nomura F, Kawata H, Mayer JE Jr: Effect of calcium and preischemic hypothermia on recovery of myocardial function after cardioplegic ischemia in neonatal lambs. J Thorac Cardiovasc Surg 105: 207-213, 1993.
50. Rebeyka I, Hanan SA, Borges MR, et al: Rapid cooling contracture of the myocardium: The adverse effect of prearrest cardiac hypothermia. J Thorac Cardiovasc Surg 100: 240-249, 1990.
51. Ruigrok TJ: Possible mechanisms involved in the development of the calcium paradox. Circ Res 61: 560-569, 1987.
52. Seeman P: The membrane actions of anesthetics and tranquilizers. Pharmacol Rev 24: 583-655, 1972.
53. Apstein CS, Gravino FN, Haudenschild CC, Kieler C: Protection of ischemic myocardium with glucose and insulin: Mechanical metabolic and morphologic correlates (Abstract). Proceedings from the St. Thomas' Hospital and Royal Postgraduate Medical School symposium: Cardioplegia: The First Quarter Century 23-25, 1980.
54. Steinberg JB, Doherty NE, Munfakh NA, et al: Oxygenated cardioplegia: The metabolic and functional effects of glucose and insulin. Ann Thorac Surg 51: 620-629, 1991.
55. de Wit L, Coetzee A, Kotze J, Lochner A: Oxygen requirements of the isolated rat heart during hypothermic cardioplegia: Effect of oxygenation on metabolic and functional recovery after five hours of arrest. J Thorac Cardiovasc Surg 95: 310-320, 1988.
56. Hearse DJ, Stewart DA, Braimbridge MV: Myocardial protection during ischemic cardiac arrest: Possible deleterious effects of glucose and mannitol in coronary infusates. J Thorac Cardiovasc Surg 76: 16-23, 1978.
57. von Oppell UO, du Toit EF, King LM, et al: St Thomas' Hospital cardioplegic solution: Beneficial effect of glucose and multidose reinfusions of cardioplegic solution. J Thorac Cardiovasc. Surg 102: 405-412, 1991.
58. Zhu Q, Yang X, Claydon MA, Hicks CL Jr, Wang T: Twenty-four hour intermittent perfusion storage of the isolated rat heart: The effect of perfusion intervals on functional preservation. J Heart Lung Transplant 13: 882-890, 1994.
59. Steigen TK, Tveita T, Korvald C, et al: Substrate preference of isolated perfused rat hearts during hypothermia and rewarming. Acta Physiol Scand 149: 143-151, 1993.
60. Segel LD, Follette DM: Cardiac function and glycogen content after twenty-four-hour preservation with various metabolic substrates. J Heart Lung Transplant 17: 299-305, 1998.
61. Segel LD, Follette DM, Contino JP, Iguidbashian JP, Castellanos LM, Berkhoff HA: Importance of substrate enhancement for long-term preservation. J Heart Lung Transplant 12: 613-623, 1993.
62. Bergmeyer HU (ed): Methods of Enzymatic Analysis. London, Academic Press, 1963, p.619.
63. Schwartz RG, Barrett EJ, Francis CK, Jacob R, Zaret BL: Regulation of myocardial amino acid balance in the conscious dog. J Clin Invest 75: 1204-1211, 1985.
64. Schwalb H, Izhar U, Yaroslavsky E, Borman JB, Uretzky G: The effect of amino acids on the ischemic heart: Improvement of oxygenated crystalloid cardioplegic solution by an enriched branched chain amino acid formulation. J Thorac Cardiovasc Surg 98: 551-556, 1989.
65. Rau E, Shine KJ, Gervais A, Douglas AM, Amos EC: Enhanced mechanical recovery of anoxic and ischemic myocardium by amino acid perfusion. Am J Physiol 236: H873-H879, 1979.
66. Peuhkurinen KL: Regulation of the tricarboxylic acid cycle pool size in heart muscle. J Mol Cell Cardiol 16: 487-495, 1984.
67. Segel LD, Follette DM, Iguidbashian JP, Contino JP, et al: Post-transplantation function of hearts preserved with fluorochemical emulsion. J Heart Lung Transplant 13: 669-680, 1994.
68. Benesch R, Triner L, Benesch RE, Kwong S, Verosky M: Enhanced oxygen unloading by an interdimerically crosslinked hemoglobin in an isolated perfused rabbit heart (Abstract). Proc Natl Acad Sci USA 81: 2941-2943, 1984.
69. Sinet M, Muffat-Joly M, Bendaace T, Pocidalo JJ: Maintaining blood pH at 7.4 during hypothermic has no significant effect on work of the isolated rat heart (Abstract). Anesthesiology 62: 582-587, 1985.
70. Serna DL, Powell LL, Wallace WC, et al: Cardiac function after 8-hour storage using PEG-Hemoglobin versus crystalloid perfusion (Abstract). ASAIO J 45: 142, 1999.
71. +] for perfusional preservation (Abstract). Transplantation 30: 409-410, 1980.
72. Buckberg GD: Studies of hypoxemic/reoxygenation injury: Linkage between cardiac function and oxidant damage. J Thorac Cardiovasc Surg 110: 1164-1170, 1995.
73. Toledo-Pereyra LH, Chee M, Lillehei RC: Effects of pulsatile perfusion pressure and storage on hearts preserved for 24 hours under hypothermia, for transplantation (Abstract). Ann Thorac Surg 27: 24-31, 1979.